Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period. It is caused by many factors, such as peripheral vein dilation, slow blood flow, long-term immobilization, bed rest and so on. On the one hand, it affects the early postoperative functional exercise and functional recovery, on the other hand, it increases the length of hospital stay and economic burden, increases the pain of patients and even endangers their lives. Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis. This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis, and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis, hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.