Clinicl Value of Combined Detection of Glycosylated Hemoglobin and Various Biochemical Indicators of Blood lipid, Blood glucose and Renal Function

Abstract

Objective: To explore the clinical values of detection results of
glycosylated hemoglobin, blood lipid, blood glucose and renal
functions and their correlation in diabetic microangiopathy and
incidence of cardiovascular and cerebrovascular diseases.
Methods: The determinations of glycosylated hemoglobin
(HbA1c), fasting plasma glucose (FPG), Urea, creatinine (Cr),
total cholesterol (TC), triglycerides (TG), and low-density
lipoprotein cholesterol (LDL-C) were carried out in 96 cases of
diabetic patients (divided into non-lesion group (50 cases) and non
-lesion group (46 cases) according to microangiopathy status) and
116 non-diabetic patients with cardiovascular and cerebrovascular
diseases (60 cases of coronary artery diseases and 56 cases of
hypertension) and the correlation of HbA1c with various
biochemical indicators. Results: in patients with diabetes, the
HbA1c with various biochemical indicators of the lesion group
saw different levels of increases compared with the non-lesion
group and there is statistically significant difference (P<0.05); the
HbA1c and FPG, Urea, TC,TG and LDL-C of the group of non-
diabetic cardiovascular and cerebrovascular diseases show a
positive correlation (P<0.05). Conclusion: The joint detection of
HbA1c and various biochemical indicators is of great significance
to the diagnosis and treatment of diabetic microangiopathy and
cardiovascular and cerebrovascular diseases.