CRISPR gene editing is a technology used to edit genomes of a variety of organisms like bacteria, animals or even human beings. Currently, there are various criticism concerning CRISPR since the technology is still immature. It’s important to address these concerns to ensure that CRISPR wouldn't cause harms to the society. The purpose of this investigation is to summarize methods which can be used to solve the risks and ethical issues regarding CRISPR through examining published researches in-depth. To draw a conclusion, scientists can use anti-crispr protein to minimize the off-target effects. For immunity issues, scientists can employ immunosuppressive drugs or to use CRISPR in places where immune system cannot reach. What’s more, given both legal and ethical hurdles, the problem of designer babies and bio-weapons are unlikely to happen. Therefore, although there are various concerns regarding CRISPR, scientists are figuring out ways to minimize the risks and to optimize the usage of the CRISPR.