Objectives: To explore the application of health management in patients with type II diabetes and to analyze and compare the incidence of chronic complications. Methods: the relevant research work was carried out in our hospital. During September 2018 to September 2019, 100 patients with type II diabetes were randomly divided into two groups: one group was given routine nursing intervention, the other group was given health management, and they were named control group and experimental group respectively. Each group had 50 patients, the influence of different nursing methods on the incidence of chronic complications in patients was explored. Results: In the one-year follow-up results, the corresponding complications of patients mainly include cardiovascular disease, kidney disease, cerebrovascular disease, fundus disease and peripheral neuropathy. The incidence of complications in the experimental group is 10.00%, while that in the control group is 32.00%. in comparison, the incidence in the experimental group is lower, and the data difference between the two group is small(P<0.05), which exists significance. Conclusion: The application of health management method in type II diabetes has significant effect, which can reduce the incidence of chronic complications, improve the quality of life of patients, and has positive significance for clinical development.