Objective: To explore the application value and nursing measuresÂ of pulse wave velocity dilution combined with continuous cardiacÂ output measurement (PICCO) and trans arterial waveform analysisÂ (Eduardo Vigileo) in continuous renal replacement therapy (CRRT)Â capacity management. Methods:Â 60 patients undergoing acuteÂ renal injury were divide into two groups, 30 randomly selectedÂ patients using PICCO for monitoring and the other 30 wereÂ monitored by Vigileo method. From the CI, SVR, SVV and otherÂ aspects of capacity management in comparison with the correlationÂ between the two. Results: There were three correlations betweenÂ CI, SVR and SVV. Conclusion: PICCO and Vigileo method haveÂ significant different in the capacity monitoring and management ofÂ patients with acute renal injury (P>0.05). However, due to theÂ measurement of parameters in PICCO technique, shrink functionÂ and hemodynamic parameters of a more comprehensive reflection.Â And the only flow of micro-trauma, do not inject ice water toÂ maintain the pipeline closed, reduce the infection is a majorÂ feature.