Abstract
Bacterial biofilm (BF) is a kind of growth way that bacteria are associated with planktonic cells in the process of growing on the body tissue or biomaterial surface to adapt to the change of living environment, composed of bacteria and extracellular matrix. After the formation of biofilm, bacteria are coated in the extracellular matrix, increased immune system of the body and antibiotic resistance, making these two mechanisms are difficult to effectively remove the infected foci, and biofilm bacteria can also continue to grow and release into blood, resulting in chronic infection and withdrawal of antibiotics after the recurrence of infection, leading to disease progression. Based on this, this paper will focus on the analysis of Staphylococcus aureus bacterial biofilm resistance mechanism, with a view to the future practical work to play a role in reference.