https://ojs.bbwpublisher.com/index.php/UR <p><em>Urology Research</em> is an academic medical journal that mainly reports on the latest scientific research results, clinical diagnosis, and treatment experiences in the field of urology. It covers both domestic and international research findings, as well as fundamental theoretical research closely related to the clinical practice of urology.</p> <p>The Journal covers all aspects of Urology&nbsp;medicine (full listing below) with an emphasis on studies that challenge the status quo of treatments and practices in Urology&nbsp;care or facilitate the translation of scientific advances into the clinic as new therapies or diagnostic tools.</p> Bio-Byword Scientific Publishing PTY LTD en-US Urology Research 2981-8230 https://ojs.bbwpublisher.com/index.php/UR/article/view/11143 <p><em>Objective</em>: To investigate the application value of urine nuclear matrix protein 22 (NMP22), osteopontin (OPN), and bladder tumor antigen (BTA) detection in the diagnostic and prognostic evaluation of bladder urothelial carcinoma. <em>Methods</em>: 100 patients with bladder urothelial carcinoma who visited our hospital from January 2020 to December 2022 were selected as the case group, and 100 healthy individuals who underwent physical examination during the same period were selected as the control group. The levels of NMP22, OPN, and BTA in the urine of the two groups were detected, and their diagnostic efficacy in bladder urothelial carcinoma was analyzed. The patients in the case group were followed up to observe the relationship between these markers and prognosis. <em>Results</em>: The levels of NMP22, OPN, and BTA in the urine of the case group were significantly higher than those of the control group (<em>P</em> &lt; 0.05). The sensitivity, specificity, and accuracy of combined detection of NMP22, OPN, and BTA for diagnosing bladder urothelial carcinoma were higher than those of single marker detection (<em>P</em> &lt; 0.05). Follow-up results showed that patients with high levels of NMP22, OPN, and BTA had a higher recurrence rate and shorter progression-free survival (<em>P</em> &lt; 0.05). <em>Conclusion</em>: Combined detection of urine NMP22, OPN, and BTA has high diagnostic value for bladder urothelial carcinoma, and the levels of these markers are correlated with patient prognosis, which can be used for prognostic evaluation.</p> Chao Li Jiqian Wang Yongchao Wang Jianping Wang Yiliang Huang Ying Chen Qinglong Wu Minghuang Rao Rongjin Fang Copyright (c) 2025 Author(s) 2025-07-11 2025-07-11 3 2 1 8 10.26689/ur.v3i2.11143 https://ojs.bbwpublisher.com/index.php/UR/article/view/11144 <p><em>Objective: </em>To explore the application of modified fluid position pads in da Vinci robotic urology lateral position surgery and analyze its clinical application value. <em>Methods: </em>A randomized controlled study was conducted from June 2024 to June 2025 to select 120 patients from the First Affiliated Hospital of Sun Yat-sen University who met the inclusion and exclusion criteria and were randomly divided into 60 cases each in the control group and the observation group. The control group used the traditional position placement method, and the observation group applied the modified fluid position pads for position placement. The two groups were compared in terms of positioning process, patient comfort, position stability, and satisfaction of surgeons. <em>Results: </em>The comfort level of the patients in the observation group was higher than that of the control group, and the positioning process could save time compared with the control group. The position stability rate in the observation group was significantly higher than that in the control group. The satisfaction of surgeons in the observation group was also higher than that in the control group. <em>Conclusion:</em> The application of the modified fluid position pads significantly simplifies the positioning process, improves the comfort and position stability of the patients, and enhances the satisfaction of the surgeons, which has important clinical promotion value.</p> Donghua Long Wenji Luo Jing Chen Youzhen Su Copyright (c) 2025 Author(s) 2025-07-11 2025-07-11 3 2 9 16 10.26689/ur.v3i2.11144