Objective: To investigate the effect of ginger slice acupoint application combined with moxibustion on chemotherapy-induced vomiting in postoperative breast cancer patients. Methods: Sixty postoperative breast cancer patients undergoing chemotherapy were randomly divided into an observation group and a control group, with 30 patients in each group. The control group received antiemetic treatment with dolasetron, while the observation group received ginger slice acupoint application combined with moxibustion in addition to antiemetic treatment to address chemotherapy-induced vomiting. The vomiting response on days 1–3 was compared between the two groups, along with R-INVR retching scores and patient satisfaction with the intervention methods. Results: On days 2 and 3 of chemotherapy, the observation group showed significantly less vomiting than the control group, with differences reaching a highly significant level (P < 0.001). On day 3, the R-INVR score in the observation group was significantly lower than that of the control group, with a highly significant difference (P < 0.001). The satisfaction score in the observation group was 8.38 ± 0.81, higher than the control group’s 7.65 ± 0.71, with a statistically significant difference (P < 0.05). Conclusion: Ginger slice acupoint application combined with moxibustion effectively alleviates chemotherapy-induced vomiting in postoperative breast cancer patients, improves quality of life, and is worth promoting clinically.
Zhang S, Gao Y, Zheng G, et al., 2016, Diagnostic Value of Two Methods for Assessing Pepsinogen in Atrophic Gastritis and Gastric Cancer. Journal of Shandong University (Medical Edition), 54(12): 46–52.
Ma H, Liu T, Liu X, et al., 2018, Correlation Analysis of Ki-67, HER2, and PHH3 Expression in Breast Cancer Tissues with the Efficacy of Neoadjuvant Chemotherapy. Chinese Journal of Cancer Prevention and Treatment, 25(10): 709–712.
Wang L, Zuo Z, Wang Y, 2019, Overview of TCM Treatment for Nausea and Vomiting Caused by Postoperative Chemotherapy in Breast Cancer Patients. World Chinese Medicine, 14(8): 1963–1968.
Zhang X, Hui C, Sun J, et al., 2018, Progress in Clinical Research on Gastrin-17. Chinese Medical Science, 8(18): 19–23 + 27.
Wang T, Fahrmann JF, Lee H, et al., 2018, JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance. Cell Metab, 27(1): 136–150.e5. https://doi.org/10.1016/j.cmet.2017.11.001. Erratum in Cell Metab, 27(6): 1357. https://doi.org/10.1016/j.cmet.2018.04.018
Lei T, He B, Zhang J, 2023, Clinical Effects of Acupoint Acupuncture Combined with Ondansetron in Treating Nausea and Vomiting Associated with Postoperative Chemotherapy in Breast Cancer. Henan Medical Research, 32(9): 1678–1681.
Wang B, Yan T, Zhang G, 2020, Prospective Randomized Controlled Study on Continued Use of Ondansetron for Preventing Postoperative Nausea and Vomiting in Breast Cancer Patients. Chinese Journal of Minimally Invasive Surgery, 20(12): 1063–1066.
Breast Cancer Committee of the Chinese Anti-Cancer Association, 2018, Clinical Practice Guidelines for the Treatment of Advanced Breast Cancer in China (2018 Edition). Chinese Journal of Oncology, 40(9): 703–713.
Cai Z, Li H, Tian X, 2020, Observation on the Efficacy of Aprepitant Combined with Ondansetron in the Treatment of Chemotherapy-Induced Nausea and Vomiting in Breast Cancer Patients: A Study of 31 Cases. Anhui Medical and Pharmaceutical Journal, 24(2): 378–380.
Su F, Cheng Z, Li L, 2020, Single-Center Randomized Controlled Study on the Prevention and Treatment of Gastrointestinal Reactions After Chemotherapy Using Warm Acupoint Application Combined with Antiemetic Drugs. Chinese Journal of New Drugs, 29(4): 408–412.
Chen Y, Chen Y, Chen H, 2021, Effect of Moxibustion Combined with Hot Ginger Slice Acupoint Application in Relieving Postoperative Chemotherapy-Induced Vomiting in Breast Cancer. Chinese and Foreign Medical Research, 19(27): 148–150.
Li X, Wang C, Zhang Y, 2020, Observation on the Efficacy of Ear Acupoint Pressure Combined with Acupuncture in Preventing and Treating Nausea and Vomiting Caused by Postoperative Chemotherapy in Breast Cancer Patients. Hebei Journal of Traditional Chinese Medicine, 42(6): 917–920.
Diao C, Wang F, 2020, Clinical Observation on the Prevention and Treatment of Gastrointestinal Reactions During Chemotherapy in Breast Cancer Patients Using Moxibustion Combined with Acupoint Application. Clinical Research in Traditional Chinese Medicine, 12(33): 51–52.