Keywords
Laparoscopic radical colorectal cancer surgery
Immune function
Efficacy
Submitted : 2024-07-10
Accepted : 2024-07-25
Published : 2024-08-09
Abstract
Objective: To explore the therapeutic effect of laparoscopic radical colorectal cancer treatment in colorectal cancer patients. Methods: A total of 50 colorectal cancer patients treated between August 2018 and August 2023 were randomly divided into two groups: Group A underwent laparoscopic radical colorectal cancer surgery, while Group B received open surgery. Clinical indicators, inflammatory factors, immune function indicators, and complications were compared between the two groups. Results: Group A showed significantly shorter operation times, faster recovery times, and reduced hospital stays compared to Group B. Additionally, Group A had less abdominal drainage and intraoperative bleeding (P < 0.05). Levels of interleukin (IL)-4, IL-6, ultrasensitive C-reactive protein (hs-CRP), and tumor necrosis factor-alpha (TNF-α) were lower in Group A compared to Group B (P < 0.05). Furthermore, immune function indicators, including CD3+, CD4+, CD8+, and CD4+/CD8+ ratios, were better in Group A (P < 0.05). The complication rate in Group A was also lower than in Group B (P < 0.05). Conclusion: Laparoscopic radical treatment for colorectal cancer is efficient and feasible, causing minimal immune function impairment and inflammatory response. It also shortens postoperative recovery time.
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