Yinqiao Sanhuang Paste Combined with Traditional Chinese Medicine Plaster for the Intervention of Drug Rash Induced by Targeted Therapy in Lung Cancer

Abstract

Objective: To observe the efficacy and safety of Yinqiao Sanhuang Paste combined with traditional Chinese medicine plaster in treating drug rash caused by targeted therapy in lung cancer. Methods: A total of 100 lung cancer patients treated at our hospital from January 2021 to December 2023 were selected and randomly divided into an observation group and a control group, with 50 patients in each group. The control group received conventional medication, while the observation group was treated with Yinqiao Sanhuang Paste combined with traditional Chinese medicine plaster. The clinical symptom improvement and adverse reactions in both groups were observed. Results: The effective rate in the control group was 80.00%, while in the observation group, it was 96.00%, with a statistically significant difference between the two groups (P < 0.05). The onset time, duration, and significant effect time in the control group were (2.41 ± 0.29) days, (4.42 ± 1.21) days, and (5.45 ± 0.29) days, respectively; in the observation group, they were (2.44 ± 0.21) days, (4.28 ± 1.11) days, and (5.57 ± 1.01) days, respectively. There was no statistically significant difference in the total onset time and total duration between the two groups (P > 0.05). The incidence of adverse reactions in the control group was 28.00%, higher than the observation group’s 10.00% (P < 0.05). Conclusion: Yinqiao Sanhuang Paste combined with traditional Chinese medicine plaster can effectively reduce the symptoms of drug rash induced by targeted therapy in lung cancer and lower the incidence of adverse reactions, indicating good clinical application value.