The three-dimensional (3D) cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development, as opposed to traditional two-dimensional cultures. These systems can induce specific cell reactions, promote specific tissue functions, and serve as valuable tools for research in tissue engineering, regenerative medicine, and drug discovery. This paper discusses current developments in the field of three-dimensional cell culture and the potential applications of 3D type 1 collagen gels to enhance the growth and maturation of dendritic cells.
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