Research on the Progress of Treating Gastroesophageal Reflux Disease with Modified Classic Traditional Chinese Medicine Prescription
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Keywords

Addition and subtraction of classic TCM prescriptions
Gastroesophageal reflux disease
Research progress
Liver and stomach stagnation heat
Qi stagnation and phlegm obstruction

DOI

10.26689/par.v8i3.7079

Submitted : 2024-05-05
Accepted : 2024-05-20
Published : 2024-06-04

Abstract

Gastroesophageal reflux disease (GERD) is a high-incidence digestive system disease. Western medicine mainly uses drugs such as proton pump inhibitors to inhibit gastric acid secretion, but some patients are accompanied by symptoms such as non-acid reflux and gas reflux, which cannot effectively treat the disease. It is necessary to actively explore other treatment schemes. Traditional Chinese medicine (TCM) has a long history of research on gastroesophageal reflux disease, which emphasizes the treatment based on syndrome differentiation as a whole. Through the treatment of various and multi-component TCM prescriptions, the patient’s body condition can be adjusted, and the treatment effect on gastroesophageal reflux disease is reliable, which has obvious therapeutic advantages. To further clarify the treatment of gastroesophageal reflux disease, this study reviewed and analyzed the research progress of the treatment of liver disease with modified prescriptions, and the report is as follows.

References

Zhu S, Li M, Wang X, et al., 2024, The Curative Effect of Rabeprazole, Trimebutine Combined with Flupentixol, and Melitracen on Non-Erosive Gastroesophageal Reflux Disease. Chinese Journal of Clinical Gastroenterology, 36(2): 85–89.

Qi M, Zhou Y, Zhang M, et al., 2023, Clinical Effect of Shugan Hewei Prescription Combined with Vonoprazan on Refractory Gastroesophageal Reflux Disease Due to Qi Depression and Phlegm Obstruction. Chinese Journal of Experimental Traditional Medical Formulae, 29(24): 146–154.

Chen S, Zhang H, Hou J, et al., 2023, Clinical Effect of Xuefu Zhuyu Decoction on Gastroesophageal Reflux Disease with Qi Stagnation and Blood Stasis Syndrome and Its Influence on Autonomic Nervous Function. Chinese Journal of Traditional Chinese Medicine, 38(11): 5621–5624.

Su L, Wang J, Wang W, 2024, Thinking of Treating Gastroesophageal Reflux Disease-Related Pharyngeal Paraesthesia from Yin Deficiency and Phlegm Turbidity. Jiangsu Traditional Chinese Medicine, 56(4): 31–34.

Xue D, Guo Z, Liu J, et al., 2024, Analysis of Professor Jiang Liangduo’s Medication Rule for Gastroesophageal Reflux Disease Based on Data Mining Technology. Journal of Shaanxi University of Traditional Chinese Medicine, 47(2): 70–75.

Du M, Chen X, Zhang X, 2024, Effect of Modified Zuojin Pill Combined with Auricular Point Therapy on Symptoms Improvement and Gastrin and Motilin Levels in Patients with Gastroesophageal Reflux Disease. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 32(3): 239–243.

Zhou X, Liu X, Zhang L, et al. Effect of Self-Made Chinese Medicine Decoction Combined with Esomeprazole Sodium on Refractory Non-Erosive Gastroesophageal Reflux Disease. Chinese Journal of Drug Abuse Prevention and Treatment, 30(3): 529–532 + 556.

Xu Z, Yang Z, Qiu W, et al., 2024, Study on the Therapeutic Effect of Zuojin Jiawei Recipe Combined with Acupuncture on Gastroesophageal Reflux Disease of Liver-Stomach Stagnation and Its Influence on Brain-Gut Peptide. Journal of Clinical Medicine in Practice, 28(5): 63–67.

Jia Z, Liu H, Liang D, et al., 2023, Curative Effect and Follow-Up Analysis of Lizhong Decoction Combined with Banxia Houpu Decoction in Treating Cold Syndrome of Elderly Gastroesophageal Reflux Disease. Hebei Journal of Traditional Chinese Medicine, 45(10): 1635–1638 + 1642.

Yu K, Zhang G, Dang Z, et al., 2023, Effect of Jiawei Platycodon grandiflorus and Fructus aurantii Decoction on Esophageal Motor Function and Gastrointestinal Hormone Level in Patients with Gastroesophageal Reflux Disease. Jilin Traditional Chinese Medicine, 43(10): 1174–1178.

Hao W, Li Y, Zhang Y, et al., 2024, Clinical Observation on the Treatment of Gastroesophageal Reflux Disease After Gastric Cancer Operation with “Zhenbeerchen Decoction”. Chinese Medicine Modern Distance Education of China, 22(6): 87–89.

Li H, Sun Z, 2024, Treating Gastroesophageal Reflux Disease of Damp-Heat Type Due to Spleen Deficiency by Activating Spleen and Regulating Stomach. China Medical Guide, 26(2): 176–180.

Guo L, Yang J, Li S, 2024, Clinical Study on Modified Chaihu Guizhi Ganjiang Decoction for Adjuvant Treatment of Gastroesophageal Reflux Disease with Liver Depression and Spleen Deficiency. Chinese Medicine Guides, 21(3): 144–148.

Zhang J, Yang X, Li D, 2024, Clinical Observation of Chaihu Zhizi Chichi Decoction Combined with Omeprazole in Treating Non-Erosive Gastroesophageal Reflux Disease Due to Stagnation of Heat in Liver and Stomach. Bulletin of Traditional Chinese Medicine, 23(1): 47–49.

Wang P, Hou T, Kang J, 2023, The Effect of Self-Made Heweishugan Decoction Combined with Routine Treatment on the Levels of Gastrointestinal Hormones and Neuropeptide Factors in Patients with Gastroesophageal Reflux Disease. China Journal of Ethnic Medicine, 29(12): 25–27.

Ni J, Xu Y, Huo L, et al., 2023, Randomized, Double-Blind Placebo-Controlled Clinical Study of Zuojin Pill in Treating Gastroesophageal Reflux Disease with Stagnation of Heat in Liver and Stomach. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 31(12): 955–960.