Plant tissue culture is a technique that enhances the quality and quantity of potatoes. Potatoes are a significant crop and are primarily used in the world. It is a staple food in many countries, where millions of tonnes are produced annually. It is an essential source of many nutrients, such as proteins, carbohydrates, vitamins, and beta-carotene. In addition, potatoes are being used as therapeutic agents against cancer and other human diseases as well. Potatoes are on the third list after wheat and rice. To overcome food shortages and malnutrition, there are two methods used for producing potatoes: the first is sexual, which is seed propagation, and the second is asexual, which is plant tissue culture propagation. Conventional potato breeding is a uniform method, but it is unsafe because there is a risk of pathogen attack. In a laboratory setting, the tissue culture of potatoes produced millions of plants with nutrient-rich medium under controlled environmental conditions that prevent pest attacks. Some environmental stresses, such as salinity and water scarcity, affect potato yield and production; however, applying nanoparticles like organic, inorganic, and silicon dioxide enhances potato quality and combats stress. Biotechnology has proven to be helpful in addressing all these issues. This review discusses the significance of potatoes, their production through the tissue culture technique, and the application of nanoparticles to improve the growth, and impact of potatoes on human health.
Badoni A, Chauhan J, 2010, Importance of Potato Micro Tuber Seed Material for Farmers of Uttarakhand Hills. International Journal of Sustainable Agriculture, 2(1): 01–09.
Bekele D, Assosa E, 2021, Application of Biotechnology on Potato Crop Improvement. GSJ, 9(8).
Barrell PJ, Meiyalaghan S, Jacobs JM, et al., 2013, Applications of Biotechnology and Genomics in Potato Improvement. Plant Biotechnology Journal, 11(8): 907–920.
Cho KS, Park YE, Park TH, 2010, Recent Advances in the Applications of Tissue Culture and Genetic Transformation in Potato. Journal of Plant Biotechnology, 37(4): 456–464.
Nahirñak V, Almasia NI, González MN, et al., 2022, State of the Art of Genetic Engineering in Potato: From the First Report to Its Future Potential. Frontiers in Plant Science, (12): 768233.
Chauhan A, Sharma D, Kumar R, et al., 2021, Methods of Propagation in Vegetable Crops, in Recent Trends in Propagation of Forrest and Horticultural Crops, Taran Publication, India, 270–281.
Mohapatra PP, Batra V, 2017, Tissue Culture of Potato (Solanum tuberosum L.): A Review. International Journal of Current Microbiology and Applied Sciences, 6(4): 489–495.
Naik PS, Buckseth T, 2018, Recent Advances in Virus Elimination and Tissue Culture for Quality Potato Seed Production. Biotechnologies of Crop Improvement, Volume 1: Cellular Approaches, Springer, Cham, 131–158.
Paul V, Buckseth T, Singh RK, et al., 2022, Alternative Methods of Seed Potato (Solanum tuberosum) Production: Indian Perspective—A Review. Current Horticulture, 10(2): 3–11.
Lone SM, Hussain K, Malik A, et al., 2020, Plant Propagation Through Tissue Culture-A Biotechnological Intervention. International Journal of Current Microbiology and Applied Sciences, 9(7): 2176–2190.
Devaux A, Goffart JP, Kromann P, et al., 2021, The Potato of the Future: Opportunities and Challenges in Sustainable Agri-Food Systems. Potato Research, 64(4): 681–720.
Bhuiyan FR, 2013, In Vitro Meristem Culture and Regeneration of Three Potato Varieties of Bangladesh. Research in Biotechnology, 4(3): 29–37.
Sudheer W, Praveen N, Al-Khayri J, et al., 2022, Role of Plant Tissue Culture Medium Components, in Advances in Plant Tissue Culture, Elsevier, Cambridge, 51–83.
Shange SBD, 2021, Application of Tissue Culture and Molecular Techniques in Disease Resistance Breeding of Grapevine, dissertation, Cape Peninsula University of Technology.
Naqqash T, Malik KA, Imran A, et al., 2024, Isolation and Characterization of Rhizobium from Non-Leguminous Potato Plants: New Frontiers in Rhizobium Research, (60): 307–325.
Ukidave VV, Ingale LT, 2022, Green Synthesis of Zinc Oxide Nanoparticles from Coriandrum sativum and their Use as Fertilizer on Bengal Gram, Turkish Gram, and Green Gram Plant Growth. International Journal of Agronomy, (8): 1–14.
Ehsanpour A, Jones M, 2001, Plant Regeneration from Mesophyll Protoplasts of Potato (Solanum tuberosum L.) Cultivar Delaware Using Silver Thiosulfate (STS). J. Sci. I. R. Iran, 12(2): 103–110.
Kikuta Y, Fujino K, Saito W, et al., 1986, Protoplast Culture of Potato: An Improved Procedure for Isolating Viable Protoplasts. Journal of the Faculty of Agriculture, Hokkaido University, 62(4): 429–439.
Sadia B, 2015, Improved Isolation and Culture of Protoplasts from S. chacoense and Potato: Morphological and Cytological Evaluation of Protoplast-Derived Regenerants of Potato cv. Desiree. Pakistan Journal of Agricultural Sciences, 52(1): 51–61.
Yasemin S, Beruto MJH, 2024, A Review on Flower Bulb Micropropagation: Challenges and Opportunities. Horticulturae, 10(3): 284.
Hamilton BM, Harwood AD, Wilson HR, et al., 2020, Are Anglers Exposed to Escherichia coli from an Agriculturally Impacted River? Environ Monit Assess, 192(4): 216.
Kapadia C, Patel NJ, 2021, Sequential Sterilization of Banana (Musa Spp.) Sucker Tip Reducing Microbial Contamination with Highest Establishment Percentage. Bangladesh Journal of Botany, 50(4), 1151–1158.
Mekonen G, Egigu MC, Muthsuwamy MJ, 2021, In vitro Propagation of Banana (Musa paradisiaca L.) Plant Using Shoot Tip Explant. Turkish Journal of Agriculture - Food Science and Technology, 9(12): 2339–2346.
Kumar M, Sirohi U, Malik S, et al., 2022, Methods and Factors Influencing In Vitro Propagation Efficiency of Ornamental Tuberose (Polianthes species): A Systematic Review of recent Developments and Future Prospects. Horticulturae, 8(11): 998.
Wahyuni DK, Huda A, Faizah S, et al., 2020, Effects of Light, Sucrose Concentration and Repetitive Subculture on Callus Growth and Medically Important Production in Justicia gendarussa Burm. f. Biotechnology Reports, (27): e00473.
Solangi N, Jatoi MA, Markhand GS, et al., 2022, Optimizing Tissue Culture Protocol for In Vitro Shoot and Root Development and Acclimatization of Date Palm (Phoenix dactylifera L.) Plantlets. Erwerbs-Obstbau, 64(1): 97–106.
Mahmoud LM, Dutt M, Shalan AM, et al., 2020, Silicon Nanoparticles Mitigate Oxidative Stress of In Vitro-Derived Banana (Musa acuminata ‘Grand Nain’) Under Simulated Water Deficit or Salinity Stress. South African Journal of Botany, (132): 155–163.
Burnett AC, Serbin SP, Davidson KJ, et al., 2021, Detection of the Metabolic Response to Drought Stress Using Hyperspectral Reflectance. Journal of Experimental Botany, 72(18): 6474–6489.
Ahmadu T, Abdullahi A, Ahmad K, et al., 2021, The Role of Crop Protection in Sustainable Potato (Solanum tuberosum L.) Production to Alleviate Global Starvation Problem: An Overview, in Solanum tuberosum - A Promising Crop for Starvation Problem, IntechOpen, London, 19–51.
Jones RA, 2021, Global Plant Virus Disease Pandemics and Epidemics. Plants (Basel), 10(2): 233.
Ozyigit II, Dogan I, Hocaoglu-Ozyigit A, et al., 2023, Production of Secondary Metabolites Using Tissue Culture-Based Biotechnological Applications. Front Plant Sci, (14): 1132555.
Al-Taleb MM, Hassawi DS, Abu-Romman SM, 2011, Production of Virus Free Potato Plants Using Meristem Culture from Cultivars Grown Under Jordanian Environment. American-Eurasian Journal of Agricultural & Environmental Sciences, 11(4): 467–472.
Marcela DO, Anca B, Danci M, 2011, Potato (Solanum tuberosum L.) Regeneration Using the Technique of Meristem Tip Culture. Journal of Horticulture, Forestry and Biotechnology, 15(4): 175–178.
Al-Selwey WA, Alsadon AA, Alenazi MM, et al., 2023, Morphological and Biochemical Response of Potatoes to Exogenous Application of ZnO and SiO2 Nanoparticles in a Water Deficit Environment. Horticulturae, 9(8): 883.
George TS, Taylor MA, Dodd IC, et al., 2017, Climate Change and Consequences for Potato Production: A Review of Tolerance to Emerging Abiotic Stress. Potato Research, (60): 239–268.
Handayani T, Gilani SA, Watanabe KN, 2019, Climatic Changes and Potatoes: How Can We Cope with the Abiotic Stresses? Breeding Science, 69(4): 545–563.
Van Dijk M, Morley T, Rau ML, et al., 2021, A Meta-Analysis of Projected Global Food Demand and Population at Risk of Hunger for the Period 2010–2050. Nature Food, 2(7): 494–501.
Giller KE, Delaune T, Silva JV, et al., 2021, The Future of Farming: Who Will Produce Our Food? Food Security, 13(5): 1073–1099.
Rosa L, Chiarelli DD, Rulli MC, et al., 2020, Global Agricultural Economic Water Scarcity. Sci Adv, 6(18): eaaz6031.
Allan RP, Barlow M, Byrne MP, et al., 2020, Advances in Understanding Large?Scale Responses of the Water Cycle to Climate Change. Annals of the New York Academy of Sciences, 1472(1): 49–75.
Naorem A, Jayaraman S, Dang YP, et al., 2023, Soil Constraints in an Arid Environment—Challenges, Prospects, and Implications. Agronomy, 13(1): 220.
Yadav S, Modi P, Dave A, et al., 2020, Effect of Abiotic Stress on Crops, in Sustainable Crop Production, IntechOpen, London, 5–16.
Seleiman MF, Al-Suhaibani N, Ali N, et al., 2021, Drought Stress Impacts on Plants and Different Approaches to Alleviate Its Adverse Effects. Plants (Basel), 10(2): 259.
Al-Selwey WA, Alsadon AA, Ibrahim AA, et al., 2023, Effects of Zinc Oxide and Silicon Dioxide Nanoparticles on Physiological, Yield, and Water Use Efficiency Traits of Potato Grown Under Water Deficit. Plants, 12(1): 218.
Al-Selwey WA, Alsadon AA, Alenazi MM, et al., 2023, Morphological and Biochemical Response of Potatoes to Exogenous Application of ZnO and SiO2 Nanoparticles in a Water Deficit Environment. Horticulturae, 9(8), 883.
Gul Z, Tang ZH, Arif M, et al., 2022, An Insight into Abiotic Stress and Influx Tolerance Mechanisms in Plants to Cope in Saline Environments. Biology (Basel), 11(4): 597.
Munaweera T, Jayawardana N, Rajaratnam R, et al., 2022, Modern Plant Biotechnology as a Strategy in Addressing Climate Change and Attaining Food Security. Agriculture & Food Security, 11(1): 1–28.
Hao S, Wang Y, Yan Y, et al., 2021, A Review on Plant Responses to Salt Stress and Their Mechanisms of Salt Resistance. Horticulturae, 7(6): 132.
Yildiz M, Poyraz ?, Çavdar A, et al., 2020, Plant Responses to Salt Stress, in Plant Breeding - Current and Future Views, IntechOpen, London.
Raddatz N, de los Ríos LM, Lindahl M, et al., 2020, Coordinated Transport of Nitrate, Potassium, and Sodium. Front. Plant Sci, (11): 522530.
Zia R, Nawaz MS, Siddique MJ, et al., 2021, Plant Survival Under Drought Stress: Implications, Adaptive Responses, and Integrated Rhizosphere Management Strategy for Stress Mitigation. Microbiological Research, (242): 126626.
Mahmoud AWM, Abdeldaym EA, Abdelaziz SM, et al., 2019, Synergetic Effects of Zinc, Boron, Silicon, and Zeolite Nanoparticles on Confer Tolerance in Potato Plants Subjected to Salinity. Agronomy, 10(1): 19.
Kafi M, Nabati J, Saadatian B, et al., 2019, Potato Response to Silicone Compounds (Micro and Nanoparticles) and Potassium as Affected by Salinity Stress. Italian Journal of Agronomy, 14(3): 162–169.
Mahmoud A, Samy M, Sany H, et al., 2022, Biochar Applications Improve Potato Salt Tolerance by Modulating Photosynthesis, Water Status, and Biochemical Constituents. Sustainability, (14): 723.
Majeed Y, Zhu X, Zhang N, et al., 2022, Functional Analysis of Mitogen-Activated Protein Kinases (MAPKs) in Potato Under Biotic and Abiotic Stress. Molecular Breeding, 42(6): 31.
Minhas JS, 2012, Potato: Production Strategies Under Abiotic Stress, in Improving Crop Resistance to Abiotic Stress, Wiley, New Jersey, 1155–1167.
Tiwari JK, Buckseth T, Zinta R, et al., 2022, Germplasm, Breeding, and Genomics in Potato Improvement of Biotic and Abiotic Stresses Tolerance. Frontiers in Plant Science, (13): 805671.
Singh A, Tiwari S, Pandey J, et al., 2021, Role of Nanoparticles in Crop Improvement and Abiotic Stress Management. J Biotechnol, (337): 57–70.
Tripathi D, Singh M, Pandey-Rai SJ, 2022, Crosstalk of Nanoparticles and Phytohormones Regulate Plant Growth and Metabolism Under Abiotic and Biotic Stress. Plant Stress, (6): 100107.
Tortella G, Rubilar O, Pieretti JC, et al., 2023, Nanoparticles as a Promising Strategy to Mitigate Biotic Stress in Agriculture. Antibiotics, 12(2): 338.
Panda MK, Singh YD, Behera RK, et al., 2020, Biosynthesis of Nanoparticles and Their Potential Application in Food and Agricultural Sector, in Green Nanoparticles, Springer, Cham, 213–225.
Zhao L, Lu L, Wang A, et al., 2020, Nano-Biotechnology in Agriculture: Use of Nanomaterials to Promote Plant Growth and Stress Tolerance. J Agric Food Chem, 68(7): 1935–1947.
Wang L, Ning C, Pan T, et al., 2022, Role of Silica Nanoparticles in Abiotic and Biotic Stress Tolerance in Plants: A Review. Int J Mol Sci, 23(4): 1947.
Gowayed M, Al-Zahrani HS, Metwali EM, 2017, Improving the Salinity Tolerance in Potato (Solanum tuberosum) by Exogenous Application of Silicon Dioxide Nanoparticles. International Journal of Agriculture and Biology, 19(1): 183–194.
Seleiman MF, Al-Selwey WA, Ibrahim AA, et al., 2023, Foliar Applications of ZnO and SiO2 Nanoparticles Mitigate Water Deficit and Enhance Potato Yield and Quality Traits. Agronomy, 13(2): 466.
Rajput VD, Minkina T, Feizi M, et al., 2021, Effects of Silicon and Silicon-Based Nanoparticles on Rhizosphere Microbiome, Plant Stress and Growth. Biology, 10(8): 791.
Roychoudhury A, 2020, Silicon-Nanoparticles in Crop Improvement and Agriculture. International Journal on Recent Advancement in Biotechnology & Nanotechnology, 3(1): 2582–1571.
Tripathi AD, Mishra R, Maurya KK, et al., 2019, Estimates for World Population and Global Food Availability for Global Health, in The Role of Functional Food Security in Global Health, Elsevier, Cambridge, 3–24.
Kimura J, Rigolot CJS, 2021, The Potential of Geographical Indications (GI) to Enhance Sustainable Development Goals (SDGs) in Japan: Overview and Insights from Japan GI Mishima Potato. Sustainability, 13(2): 961.
Burgos G, Zum Felde T, Andre C, et al., 2020, The Potato and Its Contribution to the Human Diet and Health, in The Potato Crop, Springer, Cham, 37–74.
Alcázar-Valle M, Lugo-Cervantes E, Mojica L, et al., 2020, Bioactive Compounds, Antioxidant Activity, and Antinutritional Content of Legumes: A Comparison Between Four Phaseolus Species. Molecules, 25(15): 3528.
Tsukada K, Shinki S, Kaneko A, et al., 2020, Synthetic Biology Based Construction of Biological Activity-Related Library of Fungal Decalin-Containing Diterpenoid Pyrones. Nat Commun, 11(1): 1830.
Wang DD, Li Y, Bhupathiraju SN, et al., 2021, Fruit and Vegetable Intake and Mortality: Results from 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies. Circulation, 143(17): 1642–1654.
Cruceriu D, Diaconeasa Z, Socaci S, et al., 2021, Extracts of the Wild Potato Species Solanum chacoense on Breast Cancer Cells: Biochemical Characterization, In Vitro Selective Cytotoxicity and Molecular Effects. Nutr Cancer, 73(4): 630–641.
Kheyar N, Bellik Y, Serra AT, et al., 2022, Inula viscosa Phenolic Extract Suppresses Colon Cancer Cell Proliferation and Ulcerative Colitis by Modulating Oxidative Stress Biomarkers. BioTechnologia, 103(3): 269.
Mishra T, Luthra SK, Raigond P, et al., 2020, Anthocyanins: Coloured Bioactive Compounds in Potatoes, in Potato, 173–189.
de Arruda Nascimento E, de Lima Coutinho L, da Silva CJ, et al., 2022, In Vitro Anticancer Properties of Anthocyanins: A Systematic Review. Biochim Biophys Acta Rev Cancer, 1877(4): 188748.
Hur S, Kim JH, Yun J, et al., 2020, Protein Phosphatase 1H, Cyclin-Dependent Kinase Inhibitor p27, and Cyclin-Dependent Kinase 2 in Paclitaxel Resistance for Triple Negative Breast Cancers. J Breast Cancer, 23(2): 162.
Bhushan B, Jat BS, Dagla MC, et al., 2021, Anthocyanins and Proanthocyanidins as Anticancer Agents, in Exploring Plant Cells for the Production of Compounds of Interest, Springer, Switzerland, 95–124.
Majeed T, Bhat NA, 2022, Health Benefits of Plant Extracts, in Plant Extracts: Applications in the Food Industry, Elsevier, Cambridge, 269–294.
Ahmad N, Qamar M, Yuan Y, et al., 2022, Dietary Polyphenols: Extraction, Identification, Bioavailability, and Role for Prevention and Treatment of Colorectal and Prostate Cancers. Molecules, 27(9): 2831.
Rasheed H, Ahmad D, Bao J, 2022, Genetic Diversity and Health Properties of Polyphenols in Potato. Antioxidants (Basel), 11(4): 603.
Lanteri ML, Silveyra MX, Morán MM, et al., 2023, Metabolite Profiling and Cytotoxic Activity of Andean Potatoes: Polyamines and Glycoalkaloids as Potential Anticancer Agents in Human Neuroblastoma Cells In Vitro. Food Res Int, (168): 112705.
Kowalczewski P?, Olejnik A, Wieczorek MN, et al., 2022, Bioactive Substances of Potato Juice Reveal Synergy in Cytotoxic Activity Against Cancer Cells of Digestive System Studied In Vitro. Nutrients, 15(1): 114.
Winkiel MJ, Chowa?ski S, S?oci?ska MJ, 2022, Anticancer Activity of Glycoalkaloids from Solanum Plants: A Review. Front Pharmacol, (13): 979451.
Kiokias S, Proestos C, Oreopoulou VJF, 2020, Phenolic Acids of Plant Origin—A Review on Their Antioxidant Activity In Vitro (o/w Emulsion Systems) Along with Their In Vivo Health Biochemical Properties. Foods, 9(4): 534.
Anabire EA, 2021, Effect of Foliage Removal on Root Yield, Pest Incidence and Diversity, and the Anticancer Effects of Six Sweet Potato (Ipomoea batatas) Cultivars, dissertation, North Carolina Agricultural and Technical State University.
Raigond P, Jayanty SS, Dutt SJ, 2020, New Health-Promoting Compounds in Potatoes. Food Chem, (424): 213–228.
Yan X, Li M, Chen L, et al., 2020, ??Solanine Inhibits Growth and Metastatic Potential of Human Colorectal Cancer Cells. Oncol Rep, 43(5): 1387–1396.
Zou T, Gu L, Yang L, et al., 2022, Alpha-Solanine Anti-Tumor Effects in Non-Small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway. Recent Pat Anticancer Drug Discov, 17(4): 396–409.
Prematilake D, Mendis M, 1999, Microtubers of Potato (Solanum tuberosum L.): In Vitro Conservation and Tissue Culture. J. Natn. Sci. Foundation Sri Lanka, 27(1): 17–28.
Alam P, Arshad M, Al-Kheraif AA, et al., 2022, Silicon Nanoparticle-Induced Regulation of Carbohydrate Metabolism, Photosynthesis, and ROS Homeostasis in Solanum lycopersicum Subjected to Salinity Stress. ACS omega, 7(36): 31834–31844.
Mahmoud LM, Dutt M, Shalan AM, et al., 2020, Silicon Nanoparticles Mitigate Oxidative Stress of In Vitro-Derived Banana (Musa acuminata ‘Grand Nain’) Under Simulated Water Deficit or Salinity Stress. South African Journal of Botany, (132): 155–163.
Mohamed Elhamahmy IE, Azab ES, Abdelrazik E, 2022, Molecular Characters of Potato Explants as Affected by Silicon Nanoparticles Under Drought Stress. Journal of Plant Production Sciences, 11(1): 11–32.
Nitnavare R, Bhattacharya J, Ghosh S, 2022, Nanoparticles for Effective Management of Salinity Stress in Plants, in Agricultural Nanobiotechnology, Elsevier, Cambridge, 189–216.
Rajasreelatha V, Thippeswamy M, 2023, Role of Nanoparticles on the Alleviation of Abiotic Stress Tolerance: A Review. Journal of Stress Physiology & Biochemistry, 19(4): 25–42.
Sayed EG, Mahmoud AWM, El-Mogy MM, et al., 2022, The Effective Role of Nano-Silicon Application in Improving the Productivity and Quality of Grafted Tomato Grown Under Salinity Stress. Horticulturae, 8(4): 293.
Wang L, Ning C, Pan T, et al., 2022, Role of Silica Nanoparticles in Abiotic and Biotic Stress Tolerance in Plants: A Review. International Journal of Molecular Sciences, 23(4): 1947.