Keywords
Gastric cancer
Cancer-related fatigue
Clinical effect
Submitted : 2024-01-23
Accepted : 2024-02-07
Published : 2024-02-22
Abstract
Objective: To observe the clinical effects of Jianpi Fuzheng Decoction in patients with gastric cancer and cancer-related fatigue (CRF). Methods: Using the random number table method as a reference, 68 cases of gastric CRF were randomly divided into two groups. One group served as the control group and received basic treatment, while the other was the observation group. The observation group, in addition to the control group’s treatment, received Jianpi Fuzheng Decoction. The clinical treatment effectiveness, fatigue scores, immune function indicators, and treatment safety were compared between the two groups. Results: The total clinical treatment effectiveness of the observation group and the improvement in immune function indicators after treatment were higher than those of the control group. The fatigue score after treatment was lower in the observation group than in the control group (P < 0.05). No serious adverse reactions occurred during the treatment in either group. Conclusion: Jianpi Fuzheng Decoction can enhance the clinical treatment effectiveness for gastric cancer patients with CRF. It facilitates the acceleration of fatigue symptom improvement and immune function enhancement. The medication’s safety is guaranteed, making it worthy of promotion.
References
Wang L, Dai Z, 2023, Clinical Study on Jianpi Yangrong Decoction in Treating Cancer-Induced Fatigue in Gastric Cancer. Inner Mongolia Traditional Chinese Medicine, 42(4): 40–41.
Zhu L, Guo L, Mao Z, et al., 2019, Effects of Jianpi Yishen Jiedu Recipe Combined with Chemotherapy on Cancer-Related Fatigue and Immune Function in Patients with Intermediate and Advanced Gastric Cancer. Journal of Microcirculation, 29(3): 39–44 + 48.
Ge J, Xu Y, Wang C, 2018, Internal Medicine. 9th Edition. People’s Medical Publishing House, Beijing, 364–367.
Zheng X, 2002, Guiding Principles for Clinical Research of New Traditional Chinese Medicines. China Medical Science and Technology Press, Beijing.
Xie Y, Li L, Miao W, et al., 2020, Effect of Buzhong Yiqi Decoction on Cancer-Related Fatigue and Quality of Life in Patients with Advanced Gastric Cancer. Laboratory Medicine and Clinic, 17(23): 3455–3458.
Wang Y, 2022, Clinical Study on the Treatment of Cancer-Related Fatigue in Gastric Cancer with Spleen Deficiency Type by Jianpi Fuzheng Decoction, thesis, Shandong University of Traditional Chinese Medicine.
Zhuang X, 2022, Effect of Fuzheng Jianpi Decoction Combined with Chemotherapy on Patients with Postoperative Colorectal Cancer. Chinese and Foreign Medical Research, 20(24): 122–126.
Wei B, Liu Y, 2022, Effect of Jianpi Fuzheng Decoction on Immune Function and Quality of Life in Elderly Patients with Advanced Gastric Cancer Undergoing Chemotherapy. Reflexology and Rehabilitation Medicine, 3(23): 16–19.
Yang Y, Wang W, Zeng L, 2019, Effect of Jianpi Fuzheng Decoction on Liver Function and Immune Indicators in Patients with Advanced Primary Liver Cancer. Guizhou Medicine, 43(2): 242–243.