Keywords
Non-variceal veins
Interventional embolization
Esomeprazole
Submitted : 2023-08-26
Accepted : 2023-09-10
Published : 2023-09-25
Abstract
Objective: To observe the clinical effect of emergency interventional therapy for patients with acute severe non-variceal upper gastrointestinal bleeding. Methods: 78 patients with acute severe non-variceal upper gastrointestinal bleeding who were treated in the General Hospital of the Eastern Theater Command from May 2020 to May 2023 were randomly divided into two groups according to different treatment plans. The study group underwent emergency upper gastrointestinal angiography and interventional embolization therapy, the control group was treated with esomeprazole; the clinical data related to the two groups were compared, including the total effective rate of treatment, blood pressure stabilization time, bleeding control time, etc. Results: The effective rate of clinical treatment in the study group was 97.44%, which was higher than that in the control group, which was 79.49% (P < 0.05). Both were significantly shorter (P < 0.05); the 7 d rebleeding rate and 30 d rebleeding rate of the study group were lower than those of the control group (P < 0.05); the 7 d and 30 d mortality rates of the two groups after treatment were compared, and the comparative study group was lower, but there was no significant difference (P > 0.05). Conclusion: Emergency interventional therapy can control bleeding more quickly, shorten bleeding control time and complete hemostasis time, shorten blood pressure stabilization time and abdominal pain relief time, and reduce rebleeding rate in patients with acute severe non-variceal upper gastrointestinal bleeding.
References
Wen J, Wang X, Wang M, et al., 2020, Correlation between Serum S100 Calcium Binding Protein 12 and Severity of Acute Non-Variceal Upper Gastrointestinal Bleeding. Anhui Medicine, 24(11): 2225–2229.
Chen S, Shi J, Wu M, et al., 2022, Observation on Clinical Effect of Emergency Interventional Therapy on Acute Severe Non-Variceal Upper Gastrointestinal Bleeding. Clinical Military Medical Journal, 50(7): 757–759.
Hang M, Zhang Y, Zhang L, 2018, Analysis of Clinical Characteristics and Related Factors of Acute Non-Variceal Upper Gastrointestinal Bleeding Caused by Dual Anti-Platelet Aggregation Drugs. Journal of Internal Medicine Emergency and Critical Care, 24(2): 119–121.
Wang X, Zhang X, Wu Y, et al., 2023, Research Progress on Risk Prediction of Acute Non-Variceal Upper Gastrointestinal Bleeding. Chinese Journal of Digestion, 43(1): 61–64.
Chen H, Wang Y, Li J, et al., 2023, Clinical Features and Etiological Analysis of Non-Variceal Upper Gastrointestinal Bleeding Complicated by Different Antithrombotic Drugs. Journal of Practical Clinical Medicine, 27(3): 81–85.
Chen H, Cheng C, Mu X, 2022, Clinical Effect of Endoscopic Metal Forceps in the Treatment of Elderly Non- Variceal Upper Gastrointestinal Bleeding. Chinese Journal of Gerontology, 42(5): 1099–1102.
Xiao M, Jia Y, Zheng B, et al., 2022, Value of Vascular Embolization for Rebleeding After Conventional Endoscopic Hemostasis in Acute Non-Variceal Upper Gastrointestinal Bleeding. Chinese Journal of Gastrointestinal Endoscopy, 39(7): 575–578.
Xu P, Xu H, 2020, The Sooner the Emergency Endoscopy for Non-Variceal Upper Gastrointestinal Bleeding, the Better? Journal of Gastroenterology and Hepatology, 29(12): 1408–1410 + 1415.
Feng Z, Yang J, Huang W, et al., 2023, Exploring the Red Blood Cell Transfusion Threshold in Hemodynamically Stable Patients with Non-Variceal Upper Gastrointestinal Bleeding Based on Propensity Score Matching Method. Clinical Blood Transfusion and Laboratory, 25(1): 107–111.
Dong C, Gong W, 2022, Evaluation of Clinical Advantages of Digestive Endoscopy in the Treatment of Acute Non- Variceal Upper Gastrointestinal Bleeding. Medical Diet Therapy and Health, 20(18): 51–53.
Zhang N, 2021, Clinical Analysis of 155 Cases of Acute Non-Variceal Upper Gastrointestinal Bleeding. Zhongwai Medical, 40(20): 37–39.
Chen X, Lin P, He Y, et al., 2022, Based on Tang Zonghai’s “Four Methods of Blood Treatment” to Explore the Diagnosis and Treatment of Acute Non-Variceal Upper Gastrointestinal Bleeding. World Traditional Chinese Medicine, 17(15): 2216–2218.
Chen Y, Lu S, Xie S, 2022, Interpretation of Technical Guidelines for Clinical Trials of Drugs for the Treatment of Acute Non-Variceal Upper Gastrointestinal Bleeding. Chinese Journal of Clinical Pharmacology, 38(9): 1020–1024.
Lin B, 2022, Comparison of Clinical Effects of Emergency Endoscopy and Elective Endoscopy in the Diagnosis and Treatment of Acute Non-Variceal Upper Gastrointestinal Bleeding. China Practical Medicine, 17(9): 20–22.
Guan J, Wang G, Han Y, et al., 2022, Patients with Non-Variceal Upper Gastrointestinal Bleeding who Underwent Emergency Endoscopic Hemostasis were Seriously Ill and Had Poor Prognosis. Journal of Internal Medicine Emergency and Critical Care, 28(1): 20–23.