Clinical Effect of Omeprazole Combined with Amoxicillin in the Treatment of Gastric Ulcer
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Keywords

Gastric ulcer
Amoxicillin
Omeprazole
Curative effect

DOI

10.26689/par.v7i5.5300

Submitted : 2023-08-22
Accepted : 2023-09-06
Published : 2023-09-21

Abstract

Objective: To investigate the therapeutic effect of omeprazole + amoxicillin in patients with gastric ulcers. Methods: 62 cases of patients with gastric ulcers who were treated from January 2022 to December 2022 were recruited and randomly divided into groups. Omeprazole + amoxicillin treatment was included in the study group, and amoxicillin treatment was included in the control group. The score of gastric ulcer symptoms, time of symptom resolution, gastrointestinal hormone index, and adverse reactions were compared. Results: The gastric ulcer symptom scores in the study group were lower than those in the control group (P < 0.05); the gastric ulcer symptoms and Helicobacter pylori-negative time in the study group were shorter than those in the control group (P < 0.05); the gastrointestinal hormone indexes in the study group were better than those in the control group (P < 0.05); the adverse reaction rate of gastric ulcer in the study group was lower than that in the control group (P < 0.05). Conclusion: Omeprazole + amoxicillin in the treatment of gastric ulcers can regulate gastrointestinal hormones, relieve gastric ulcer symptoms, and shorten the duration of ulcers, which is highly effective and feasible.

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