Clinical Effect of Omeprazole Combined with Amoxicillin in the Treatment of Gastric Ulcer
Download PDF
$currentUrl="http://$_SERVER[HTTP_HOST]$_SERVER[REQUEST_URI]"

Keywords

Gastric ulcer
Amoxicillin
Omeprazole
Curative effect

DOI

10.26689/par.v7i5.5300

Submitted : 2023-08-27
Accepted : 2023-09-11
Published : 2023-09-26

Abstract

Objective: To investigate the therapeutic effect of omeprazole + amoxicillin in patients with gastric ulcers. Methods: 62 cases of patients with gastric ulcers who were treated from January 2022 to December 2022 were recruited and randomly divided into groups. Omeprazole + amoxicillin treatment was included in the study group, and amoxicillin treatment was included in the control group. The score of gastric ulcer symptoms, time of symptom resolution, gastrointestinal hormone index, and adverse reactions were compared. Results: The gastric ulcer symptom scores in the study group were lower than those in the control group (P < 0.05); the gastric ulcer symptoms and Helicobacter pylori-negative time in the study group were shorter than those in the control group (P < 0.05); the gastrointestinal hormone indexes in the study group were better than those in the control group (P < 0.05); the adverse reaction rate of gastric ulcer in the study group was lower than that in the control group (P < 0.05). Conclusion: Omeprazole + amoxicillin in the treatment of gastric ulcers can regulate gastrointestinal hormones, relieve gastric ulcer symptoms, and shorten the duration of ulcers, which is highly effective and feasible.

References

Du H, 2020, Comparison of the Effect of Pantoprazole and Omeprazole Combined with Clarithromycin and Amoxicillin in the Treatment of Helicobacter pylori Positive Duodenal Ulcer. Shanxi Medical Journal, 49(21): 2937–2938.

Wang H, 2022, Analysis of the Clinical Effect of Amoxicillin, Clarithromycin Combined with Esomeprazole in the Treatment of Gastric Ulcer Patients with Helicobacter pylori Infection. Frontiers of Medicine, 12(6): 15–17.

Song Z, Li B, 2022, Clinical Effect of Rabeprazole Combined with Clarithromycin and Amoxicillin in the Treatment of Gastric Ulcer. Chinese Journal of Clinical Rational Drug Use, 15(7): 67–69.

Suo N, 2020, Observation on the Curative Effect of Amoxicillin, Clarithromycin Combined with Lansoprazole in the Treatment of Duodenal Ulcer Complicated with Helicobacter pylori Infection. Chinese Journal of Clinical Rational Drug Use, 13(1): 93–95.

Wang X, 2022, Study on the Effect of Rabeprazole and Clarithromycin Combined with Amoxicillin in the Treatment of Gastric Ulcer. Chinese Modern Drug Application, 16(6): 126–128.

Sun A, 2022, Evaluation of the Effect of Omeprazole + Amoxicillin in the Treatment of Patients with Gastric Ulcer. Chinese and Foreign Women’s Health Research, 8(23): 33–34 + 58.

Wang D, 2022, The Effect of Amoxicillin Combined with Omeprazole on the Adverse Reaction Rate and Symptom Improvement Time in Patients with Gastritis and Gastric Ulcer. Chinese Science and Technology Journal Database (Digest Edition) Medicine and Health, 4(5): 70–72.

Cao Y, 2022, The Effect of Omeprazole Combined with Amoxicillin in the Treatment of Gastritis Complicated with Gastric Ulcer. Chinese Science and Technology Journal Database (Citation Edition) Medicine and Health, 7(10): 57–59.

Chen X, 2022, Study on the Value of Omeprazole Combined with Amoxicillin in the Treatment of Patients with Gastritis Complicated with Gastric Ulcer. Chinese Science and Technology Journal Database (Full Text Version) Medicine and Health, 4(2): 84–86.

Yang H, 2022, Analysis of the Clinical Effect Difference between Omeprazole and Amoxicillin in the Treatment of Gastric Ulcer. Chinese Science and Technology Journal Database (Full Text Version) Medicine and Health, 5(12): 67–69.