Dosimetric Comparative Analysis of Volumetric Modulated Arc Therapy and Intensity-Modulated Radiation Therapy in Cervical Cancer
Download PDF

Keywords

Volumetric modulated arc therapy
Intensity-modulated radiation therapy
Radiotherapy for cervical cancer
Dose

DOI

10.26689/par.v7i3.4937

Submitted : 2023-04-29
Accepted : 2023-05-14
Published : 2023-05-29

Abstract

Objective: To carry out dosimetric comparison between volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) in cervical cancer. Methods: 50 postoperative cervical cancer patients were included in this study. The patients were admitted for treatment from January 2021 to January 2022. VMAT and IMRT plans were designed for each patient to analyze the dose distribution in the target area of the two treatment techniques. Results: Comparing the monitor unit for single treatment (638.21 ± 116.21 MU) and time of single treatment (143.21 ± 23.14 s) in the observation group and the monitor unit for single treatment (932.14 ± 74.11 MU) and time of single treatment (223.14 ± 17.26 s) in the control group, there was significant difference (P < 0.05); there was also significant difference (P < 0.05) between the normal tissue (bladder and rectum) of the observation group and that (bladder and rectum) of the control group. Conclusion: VMAT is more effective in cervical cancer, and it has a certain protective effect on normal tissues in patients and can reduce the radiation dose.

References

Su X, Hu Y, Gu X, et al., 2021, Dosimetric Differences Between Volume-Rotating Intensity-Modulated and Three-Dimensional Conformal Intensity-Modulated Radiotherapy Techniques After Cervical Cancer Surgery. Modern Oncology Medicine, 29(4): 675–678.

Han Y, Mao K, Dai T, et al., 2019, Dosimetric Comparison of Rotational Intensity Modulation and Intensity Modulated Radiation Therapy in Radiotherapy for Cervical Cancer in Prone Position. Journal of China-Japan Friendship Hospital, 33(5): 277–280.

Zheng P, Wang D, 2022, Volumetric Modulated Arc Therapy Dose Prediction of Bladder and Rectum for Cervical Cancer Based on Dose-Volume Histogram. Journal of Radiation Research and Radiation Technology, 40(5): 41–47.

Liu X, 2021, Dosimetric Characteristics of Volumetric Modulated Arc Therapy and Intensity-Modulated Radiation Therapy After Cervical Cancer Surgery. Medical Equipment, 34(17): 100–102.

Deng J, Wu X, Chang X, et al., 2022, Influence of Field Isocenter Selection on Dosimetry of Cervical Cancer in Volumetric Modulated Arc Therapy. Modern Oncology, 30(1): 101–106.

Liu X, 2021, Dosimetric Characteristics of Volumetric Modulated Arc Therapy and 9-Field Intensity-Modulated Radiation Therapy in Patients with Intracranial Nasopharyngeal Carcinoma. Medical Equipment, 34(18): 5–7.

Hu L, Zhang J, Zhou M, et al., 2022, Dosimetric Study of Volumetric Modulated Arc Therapy and Fixed-Field Intensity-Modulated Radiotherapy in Postoperative Radiotherapy for Ovarian-Sparing Cervical Cancer. Practical Cancer Journal, 37(11): 1851–1854.

Zhou Y, Xu Z, Jiang X, et al., 2022, Study on the Effect of Actual Exposure Dose to Bladder and Rectum in Intensity Modulated Radiation Therapy for Cervical Cancer. Journal of Clinical Military Medicine, 50(2): 194–195 + 198.