Relationship Between Postprandial Blood Glucose, Fasting Insulin, and Glycated Hemoglobin Levels and Early Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus
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Keywords

Type 2 diabetes mellitus
Diabetic nephropathy
Postprandial blood glucose

DOI

10.26689/par.v7i2.4797

Submitted : 2023-04-30
Accepted : 2023-05-15
Published : 2023-05-30

Abstract

Objective: To investigate the relationship between postprandial blood glucose (PBG), fasting insulin (FINS), and glycated hemoglobin (HbA1c) levels and early diabetic nephropathy in patients with type 2 diabetes. Methods: 96 cases of type 2 diabetes mellitus treated in our hospital from May 2021 to May 2022 were selected as the research subjects. The patients were divided into two groups according to the urinary albumin excretion rate (UAER), with 53 cases in the type 2 diabetes group (UAER < 30 ?g/min) and 43 cases in the early diabetic nephropathy group (30 ?g/min ? UAER < 300 ?g/min). PBG, FINS, and HbA1c levels were detected in 87 healthy patients. Results: The levels of PBG, FINS, and HbA1c in the early diabetic nephropathy group were higher than those in the control group (P < 0.01) and the type 2 diabetes group (P < 0.01). Conclusion: PBG, FINS, and HbA1c are factors affecting the occurrence of diabetic nephropathy in patients with type 2 diabetes; thus, controlling the levels of PBG, FINS, and HbA1c can effectively prevent the occurrence of diabetic nephropathy in type 2 diabetes mellitus.

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