Keywords
Interference
Biochemical detection
Submitted : 2023-04-30
Accepted : 2023-05-15
Published : 2023-05-30
Abstract
Objective: To explore the interference of monoclonal immunoglobulin (M protein) on the detection of serum LDL-C in patients with multiple myeloma, improve the understanding of this matter, determine and establish the correct method, and provide more accurate clinical results through this case. Methods: A case was selected for analysis by the direct method. Results: The interference of IgG kappa-type M protein on LDL-C detection could not be completely eliminated by the enzymatic method. Conclusion: IgG-type type M protein affects the detection of LDL-C by the enzymatic method; thus, light reagents can be used with the direct method for detection.
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