Objective: To explore an effective treatment for spontaneous progressive hemopneumothorax in young people. Methods: Thirty-four young patients with spontaneous progressive hemopneumothorax from January 2018 to December 2019 were selected to be included in the control group for retrospective analysis; from January 2020 to December 2021, 69 young patients with spontaneous progressive hemopneumothorax were selected to be included in the study group. The control group was treated with double-port thoracoscopic bullectomy, whereas the study group was treated with single-port thoracoscopic bullectomy. The intraoperative blood loss, operation time, tube retention time, VAS score, postoperative air leakage, and 1-year recurrence of the patients in the two groups were observed and analyzed. Results: The perioperative conditions of the patients in the study group, including intraoperative bleeding loss, operation time, tube retention time, and VAS scores, were 15.12 ± 1.36, 54.69 ± 18.78, 2.14 ± 0.98, and 3.25 ± 0.14, respectively. The perioperative conditions of the patients in the control group, including intraoperative bleeding loss, operation time, tube retention time, and VAS scores, were 22.69 ± 2.01, 55.36 ± 19.01, 4.21 ± 1.01, and 5.36 ± 0.45, respectively; other than the operation time, the differences in intraoperative blood loss, tube retention time, and VAS scores between the two groups were statistically significant (p < 0.05); after the surgery, two patients in the study group had postoperative air leakage, accounting for 2.90% and another two patients had recurrence one year after the surgery, accounting for 2.90%; on the other hand, three patients in the control group had postoperative air leakage, accounting for 8.82%, and two patients had recurrence one year after the surgery, accounting for 5.88%. However, ?2 test showed that p > 0.05. Conclusion: Treatment of spontaneous progressive hemopneumothorax in young people is better with single-port thoracoscopic bullectomy than with two-port thoracoscopic bullectomy, which effectively reduces intraoperative bleeding. The pain level is significantly better with single-port thoracoscopic bullectomy than with two-port thoracoscopic bullectomy, and the prognosis of patients is good with a low probability of recurrence for both, single- and two-port thoracoscopic bullectomy.
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