In recent years, seeking effective anti-angiogenic components and therapeutic methods from traditional Chinese Medicine (TCM) has been a hot spot in the treatment of malignant tumors. In particular, the active ingredients found in Chinese herbal extracts have shown strong inhibition of tumor neovascularization.
Folkman J, 1971, Tumor Angiogenesis: Therapeutic Implications. The New England Journal of Medicine, 285(21): 1182-1186.
Folkman J, 1972, Anti-Angiogenesis: New Concept for Therapy of Solid Tumors. Annals of Surgery, 175(3): 409-416.
Dimova I, Popivanov G, Djonov V, 2014, Angiogenesis in Cancer – General Pathways and Their Therapeutic Implications. Journal of BUON: Official Journal of the Balkan Union of Oncology, 19(1): 15-21.
Ribatti D, Nico B, Crivellato E, et al., 2007, The History of the Angiogenic Switch Concept. Leukemia, 21(1): 44-52.
Dor Y, Porat R, Keshet E, 2001, Vascular Endothelial Growth Factor and Vascular Adjustments to Perturbations in Oxygen Homeostasis. American Journal of Physiology Cell Physiology, 280(6): 1367-1374.
Zhang T, Sun X, 2016, Mind and Brain Government Apirit: Understanding the Integration of Mind and Brain. Chinese Journal of Rehabilitation Theory and Practice, 22(003): 368-370.
Cheng H, 2014, Discussion on the Theory of Cancer Virus and Pathogenesis. Journal of Traditional Chinese Medicine, 55(20): 1711-1714.
Tie M, Zhang Y, 2014, Discussion on the Mechanism of Promoting Blood Circulation and Removing Stasis to Normalize Tumor Vessels. West China Medical Journal, (12): 2379-2381.
Zheng W, Yang X, Wu L, et al., 2007, Discussion on the Molecular Mechanism of Curcumin Against Angiogenesis. Chinese Journal of Clinical Oncology, 34(12): 683-685.
Gururaj AE, Belakavadi M, Venkatesh DA, et al., 2002, Molecular Mechanisms of Anti-Angiogenic Effect of Curcumin. Biochemical & Biophysical Research Communications, 297(4): 934-942.
Ortiz LM, Lombardi P, Tillhon M, et al., 2014, Berberine, an Epiphany Against Cancer. Molecules, 19(8): 12349-12367.
Jin F, Xie T, Huang X, et al., 2018, Berberine Inhibits Angiogenesis in Glioblastoma Xenografts by Targeting the VEGFR2/ERK Pathway. Pharmaceutical Biology, 56(1): 665-71.
Liu J, Zhang D, Chen M, et al., 2011, Inhibition of Angiogenesis by Arenobufagin. Acta Pharmaceutica Sinica, (05): 527-533.
Li M, Wu S, Liu Z, et al., 2012, Arenobufagin, a Bufadienolide Compound from Toad Venom, Inhibits Vegf-Mediated Angiogenesis Through Suppression of Vegfr-2 Signaling Pathway. Biochemical Pharmacology, 83(9): 1251-1260.
Lee DY, Yasuda M, Yamamoto T, et al., 1997, Bufalin Inhibits Endothelial Cell Proliferation and Angiogenesis In Vitro. Life Sciences, 60(2): 127-134.