Research Progress of Anti-Tumor Angiogenesis in Traditional Chinese Medicine
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Keywords

Traditional Chinese medicine
Tumor
Anti-angiogenic
Overview

DOI

10.26689/par.v5i6.2797

Submitted : 2021-10-31
Accepted : 2021-11-15
Published : 2021-11-30

Abstract

In recent years, seeking effective anti-angiogenic components and therapeutic methods from traditional Chinese Medicine (TCM) has been a hot spot in the treatment of malignant tumors. In particular, the active ingredients found in Chinese herbal extracts have shown strong inhibition of tumor neovascularization.

References

Folkman J, 1971, Tumor Angiogenesis: Therapeutic Implications. The New England Journal of Medicine, 285(21): 1182-1186.

Folkman J, 1972, Anti-Angiogenesis: New Concept for Therapy of Solid Tumors. Annals of Surgery, 175(3): 409-416.

Dimova I, Popivanov G, Djonov V, 2014, Angiogenesis in Cancer – General Pathways and Their Therapeutic Implications. Journal of BUON: Official Journal of the Balkan Union of Oncology, 19(1): 15-21.

Ribatti D, Nico B, Crivellato E, et al., 2007, The History of the Angiogenic Switch Concept. Leukemia, 21(1): 44-52.

Dor Y, Porat R, Keshet E, 2001, Vascular Endothelial Growth Factor and Vascular Adjustments to Perturbations in Oxygen Homeostasis. American Journal of Physiology Cell Physiology, 280(6): 1367-1374.

Zhang T, Sun X, 2016, Mind and Brain Government Apirit: Understanding the Integration of Mind and Brain. Chinese Journal of Rehabilitation Theory and Practice, 22(003): 368-370.

Cheng H, 2014, Discussion on the Theory of Cancer Virus and Pathogenesis. Journal of Traditional Chinese Medicine, 55(20): 1711-1714.

Tie M, Zhang Y, 2014, Discussion on the Mechanism of Promoting Blood Circulation and Removing Stasis to Normalize Tumor Vessels. West China Medical Journal, (12): 2379-2381.

Zheng W, Yang X, Wu L, et al., 2007, Discussion on the Molecular Mechanism of Curcumin Against Angiogenesis. Chinese Journal of Clinical Oncology, 34(12): 683-685.

Gururaj AE, Belakavadi M, Venkatesh DA, et al., 2002, Molecular Mechanisms of Anti-Angiogenic Effect of Curcumin. Biochemical & Biophysical Research Communications, 297(4): 934-942.

Ortiz LM, Lombardi P, Tillhon M, et al., 2014, Berberine, an Epiphany Against Cancer. Molecules, 19(8): 12349-12367.

Jin F, Xie T, Huang X, et al., 2018, Berberine Inhibits Angiogenesis in Glioblastoma Xenografts by Targeting the VEGFR2/ERK Pathway. Pharmaceutical Biology, 56(1): 665-71.

Liu J, Zhang D, Chen M, et al., 2011, Inhibition of Angiogenesis by Arenobufagin. Acta Pharmaceutica Sinica, (05): 527-533.

Li M, Wu S, Liu Z, et al., 2012, Arenobufagin, a Bufadienolide Compound from Toad Venom, Inhibits Vegf-Mediated Angiogenesis Through Suppression of Vegfr-2 Signaling Pathway. Biochemical Pharmacology, 83(9): 1251-1260.

Lee DY, Yasuda M, Yamamoto T, et al., 1997, Bufalin Inhibits Endothelial Cell Proliferation and Angiogenesis In Vitro. Life Sciences, 60(2): 127-134.