Keywords
Targeted therapy
Non-small cell lung cancer
Submitted : 2021-10-31
Accepted : 2021-11-15
Published : 2021-11-30
Abstract
Objective: To evaluate the clinical efficacy of gefitinib in non-small cell lung cancer. Methods: A total of 45 patients with non-small cell lung cancer who received treatment in Taizhou Second People’s Hospital from January 2018 to January 2020 were selected as the subjects in this study, in which all of them were treated with gefitinib. Its efficacy and safety were evaluated. Results: The objective response rate was 53.33% and the disease control rate was 84.44%. After treatment, the levels of tumor markers were measured again, of which the levels of CA125 and CEA were significantly lower than before (P < 0.05). After treatment, the patients’ CD3+, CD4+, and CD4+/CD8+ were significantly lower than those before treatment, and CD8+ was significantly higher (P < 0.05). Conclusion: Gefitinib, which is a targeted therapy for non-small cell lung cancer, can reduce the level of serum tumor markers and improve the immune function. The curative effect is good, but more emphasis should be on the adverse reactions caused by a single drug use.
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