Clinical Manifestations and Maternal and Infant Outcomes of Pregnancy Complicated with Thrombocytopenia

Abstract

Objective: To explore the clinical manifestations as well as maternal and infant outcomes of pregnancy complicated with thrombocytopenia. Methods: A total of 478 pregnant women with thrombocytopenia, treated in Shaanxi Provincial People’s Hospital from July 2019 to June 2021, were selected as the research group, while 200 normal pregnant women, treated during the same period, were selected as the control group to analyze gestational thrombocytopenia (GT), idiopathic thrombocytopenic purpura (ITP), pregnancy-induced hypertension (PIH), adverse maternal and infant outcomes, etc. Results: Among the 478 patients in the research group, the main causes of pregnancy complicated with thrombocytopenia were GT, ITP, and PIH, accounting for 75.51%, 6.49%, and 8.79%, respectively, while other causes accounted for 9.21%. There was no significant difference between the research group and the control group in the amount of intrapartum bleeding, premature delivery, stillbirth, thrombocytopenia, and neonatal asphyxia, but there was significant difference in the mode of delivery (P < 0.05). Conclusion: The traditional indexes of coagulation function are not abnormal with decreased platelets in pregnant women with thrombocytopenia, but the indexes of thromboelasticity are abnormal and can reflect the changes of coagulation function. The cesarean section rate of patients with thrombocytopenia in pregnancy increases with the decrease of platelet count, but the mode of delivery should be determined in consideration of specific conditions.