Analysis of Microsatellite Instability in Colorectal Cancer and Precursor Lesions
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Keywords

Colorectal cancer
Adenomas
Polyps
Microsatellite instability

DOI

10.26689/par.v5i4.2314

Submitted : 2021-06-30
Accepted : 2021-07-15
Published : 2021-07-30

Abstract

In many countries, colorectal cancer is one of the common cancers. It has been confirmed that microsatellite instability (MSI) is one of the most important molecular changes in colorectal cancer. As the recognized precursor lesions of colorectal cancer, adenomas and some polyps also have MSI phenomenon. This article analyzes the MSI of colorectal cancer and its closely related adenomas and polyps in domestic and foreign literature, and further discusses how to identify colorectal cancer at an early stage and the impact of MSI on the prognosis and treatment of colorectal cancer.

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