Abstract
Objective: To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection. Methods: From June 2019 to November 2020, 96 patients with Helicobacter pylori infection were selected and randomly assigned Combined treatment with omeprazole, amoxicillin and clarithromycin was named group A; Group B was treated with omeprazole, amoxicillin, clarithromycin and colloidal bismuth pectin; Group C was given omeprazole, amoxicillin, clarithromycin and metronidazole. Results: The symptom score and gastroscope score of group B or C were lower than those of group A (P < 0.05); The incidence of adverse reactions and HP eradication rate in group C were lower than those in group B, and those in group B were lower than those in group A (P < 0.05); The quality of life score of group C was higher than that of group B, and that of group B was higher than that of group A, P < 0.05. Conclusions: The sequential therapy of omeprazole, amoxicillin, clarithromycin and metronidazole in patients with Helicobacter pylori infection can improve the HP eradication rate, improve the quality of life of patients, which is safe and efficient.