Objective: To explore the causes, diagnosis and treatment of gastric paralysis after radical resection of colon cancer. Methods: A retrospective analysis was performed on the clinical data of 12 cases of patients with gastroparesis syndrome after colon cancer surgery in our department from January, 2011 to December, 2013. Results: Gastric paralysis after radical resection of colon cancer is caused by multiple factors and its incidence is linked to factors like nervous and mental factors, surgical traumas, post-surgical metabolic disorders and anesthesia drugs and other factors. All patients are healed with non-surgical treatment. Conclusions: Comprehensive and conservative treatments are carried out for gastric paralysis after radical resection of colon cancer and satisfactory curative effects can be obtained. Surgical treatment should be chosen carefully and considerately.