Keywords
Calcium dobesilate
Shenqi Dihuang Decoction
Syndrome score
Submitted : 2025-07-09
Accepted : 2025-07-24
Published : 2025-08-08
Abstract
Objective: To evaluate the therapeutic effect of Shenqi Dihuang Decoction combined with calcium dobesilate on patients with diabetic nephropathy (DKD). Methods: 90 patients with DKD who visited the hospital from March 2024 to March 2025 were selected as samples and randomly divided into two groups. Group A was treated with Shenqi Dihuang Decoction combined with calcium dobesilate, while Group B was treated with calcium dobesilate alone. The efficacy, syndrome scores, blood glucose levels, and renal function indicators were compared between the two groups. Results: The efficacy of DKD treatment in Group A was higher than that in Group B (P < 0.05). The syndrome scores in Group A were lower than those in Group B (P < 0.05). The 2-hour postprandial blood glucose (PBG), fasting blood glucose (FBG), and glycated hemoglobin (HbA1c) levels in Group A were lower than those in Group B (P < 0.05). The serum creatinine (SCr), urinary microalbumin, urinary albumin excretion rate (UAER), and β2-microglobulin (β2-MG) levels in Group A were also lower than those in Group B (P < 0.05). Conclusion: The treatment of DKD with Shenqi Dihuang Decoction combined with calcium dobesilate can stabilize blood glucose levels, improve renal function, and reduce syndrome scores, which is highly effective and feasible.
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