Objective: To study the characteristics of elderly patients with prostate cancer, and to analyze the effect of lipid metabolism regulation on patients’ treatment. Method: 60 elderly patients with prostate cancer were randomly selected. For the observation group, collected the data, adjusted with lipid metabolism and treated conventionally. For the control group, collected the data and treated conventionally. Results: PSA, TG, TC, the total effective rate and adverse reactions were significantly improved after 12 months of treatment(P<0.05). Conclusion: The effect of lipid metabolism regulation on elderly patients with prostate cancer treatment is satisfactory.