Objective: To analyze the efficacy of laparoscopic resection of anterior rectal cancer in treating rectal cancer. Methods: Fifty patients with rectal cancer who were treated in Gucheng County Hospital of Hebei Province from September 2017 to September 2019 were selected and recruited in the present study. These patients were divided into two groups, namely the control group and observation groups, by random number table method. Each group consisted of 25 patients. The control group underwent laparoscopic assisted transanorectal mesorectal excision, whereas the observation group underwent laparoscopic resection of anterior rectal cancer. The two groups were compared for related indicators, indicators pertaining to postoperative recovery, and complications. Results: There was no significant difference in the number of lymph node dissections between the two groups (P>0.05). The amount of intraoperative blood loss, surgical operation time, and incision length in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). The time of getting out of bed, anal exhaust, and duration of hospital stay were shorter in the observation group than those of the control group, and the differences were statistically significant (P<0.05). In addition, the incidence of postoperative complications in the observation group was lower than that in the control group, and the differences were statistically significant (P<0.05). Conclusions: Laparoscopic resection of anterior rectal cancer is effective for rectal cancer patients. This treatment method can effectively reduce the amount of intraoperative bleeding, shorten the operation time, the time of anal exhaust, get out of bed, and the length of hospital stay, as well as improve condition of the patients.