Effect of Dahuang Mudan Decoction to Supplement the Treatment of Acute Appendicitis and its Effect on Serum TNF-α level
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Keywords

Acute appendicitis
Dahuang Mudan Decoction
TNF alpha level

DOI

10.26689/otd.v2i2.7434

Submitted : 2024-06-18
Accepted : 2024-07-03
Published : 2024-07-18

Abstract

Objective: To supplement Dahuang Mudan Decoction therapeutic formula in the surgical treatment of acute appendicitis, and to observe its effect on patients’ serum TNF-α levels. Methods: 60 patients with acute appendicitis who underwent laparoscopic appendectomy were divided into two groups (admitted in January-October 2023) by randomization grouping method; the control group was supplemented with conventional treatment, and the observation group was supplemented with Dahuang Mudan Decoction treatment. Comparison of traditional Chinese medicine (TCM) evidence points, postoperative gastrointestinal recovery, inflammatory factor levels, and postoperative complication problems were compared between the two groups. Results: After treatment, all TCM evidence points, inflammatory factor levels, and complication rates of the observation group were lower than those of the control group, and the recovery time of postoperative bowel sounds, the time of the first flatulence and defecation were shorter than those of the control group (P < 0.05). Conclusion: The effect of Dahuang Mudan Decoction plus a reduction in the adjuvant treatment of acute appendicitis is reliable, can actively reduce the serum TNF-α level, and promote faster and better recovery of patients.

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