Keywords
Radiotherapy
Skin reaction
Radiotherapy skin protective agent
Submitted : 2024-04-07
Accepted : 2024-04-22
Published : 2024-05-07
Abstract
Objective: To analyze the application effect of radiotherapy skin protective agents on skin reactions in patients with nasopharyngeal carcinoma radiotherapy. Methods: One hundred and twenty nasopharyngeal cancer patients admitted to the hospital from January 2017 to January 2023 were randomly divided into a control group and an observation group of 60 cases each. Both groups received radiotherapy. The control group received traditional intervention methods while the observation group received traditional intervention methods combined with radiation therapy and skin protective agent intervention. The skin reactions, pain, comfort, and quality of life were compared between the two groups. Results: Both groups of patients had skin reactions, but the severity of skin reactions in the observation group was lower than that in the control group (P < 0.05). On the last day of radiotherapy, the pain score of the observation group was lower than that of the control group, and the comfort score was higher than that of the control group (P < 0.05). The total quality of life scores of the patients in the observation group were higher than those in the control group (P < 0.05). Conclusion: In treating skin reactions in patients with nasopharyngeal carcinoma undergoing radiotherapy, the application of radiotherapy skin protective agents reduced skin damage and pain and increased their quality of life.
References
Wang X, Chen Y, Fei M, et al., 2023, Effects of Mouth-Opening Exercise Combined with Skin Care on Oral Mucosal Reaction and Quality of Life in Patients with Nasopharyngeal Carcinoma Radiotherapy. Qilu Nursing Journal, 29(6): 154–156.
Liu M, Chang W, 2023, Effect of Using Radiotherapy Skin Protective Agents to Treat Skin Reactions in Patients Undergoing Radiotherapy for Nasopharyngeal Carcinoma. Chinese Health Standards Management, 14(2): 136–139.
Wang D, 2021, Correlation Between Serum 25(OH)D3 Levels and Radiation-Induced Skin Damage in Elderly Patients Undergoing Radiotherapy for Nasopharyngeal Carcinoma. Chinese Journal of Gerontology, 41(6): 1179– 1182.
Jiao J, 2021, The Improvement Effect of Standardized Skin Care Regimen on Dermatitis in Patients with Nasopharyngeal Carcinoma Radiotherapy. International Journal of Nursing, 40(16): 2973–2975.
Chen Z, Zhong Q, Chen Y, et al., 2021, Application of Bundled Nursing Intervention in Preventing and Treating Radiation Dermatitis in Patients with Nasopharyngeal Cancer. China Medical Herald, 18(34): 172–175 + 184.
Chen H, Ding R, Zhang R, et al., 2021, Analysis of the Current Knowledge, Belief, and Behavior of Radiation Dermatitis in Patients with Nasopharyngeal Cancer Radiotherapy and Factors Affecting their Behavior. Chinese Journal of Practical Nursing, 37(12): 924–929.
Wu H, Tang X, Zhang B, et al., 2023, Observation on the Efficacy of Fumigation with Heat-Clearing, Cooling- Blood, and Detoxification Prescription in Treating Patients with Nasopharyngeal Carcinoma in The Acute Phase of Radiation Dermatitis. World Journal of Integrated Traditional Chinese and Western Medicine, 18(12): 2503–2507.
He J, Gao J, Qian L, 2021, Research Progress on Acute Radiation Dermatitis in Nasopharyngeal Carcinoma. Chinese Journal of Radiation Oncology, 30(3): 311–315.
Peng S, Lu J, Zhou Q, et al., 2022, Evaluation of the Effect of PG-SGA-Led Nutritional Intervention on Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy and Chemotherapy. Journal of Xuzhou Medical University, 42(5): 326–329.
Zhou J, Mo C, Xu J, et al., 2023, Research on Applying A Full-Process Management Model Based on Maxillofacial and Oral Massage Technology in Patients with Nasopharyngeal Cancer Radiotherapy. Chinese Nursing Management, 23(12): 1768–1774.
Iwai T, Imagumbai T, Okabayashi S, et al., 2023, Perianal Bowen’s Disease Treated with Radiotherapy Preserving Anal Function with A Unique Skin Reaction Considered as ‘Tumoritis.’ International Cancer Conference Journal, 12(1): 41–45.