Keywords
Serum indicators
Papillary thyroid carcinoma
Submitted : 2024-02-28
Accepted : 2024-03-14
Published : 2024-03-29
Abstract
Objective: To analyze the value of ultrasound imaging combined with serum indicators in evaluating the invasiveness of papillary thyroid cancer (PTC). Methods: One hundred and fifty patients with papillary thyroid cancer admitted to our hospital from September 2019 to December 2022 were selected. Pathological tissue testing was performed on all patients. According to the size, shape, boundary, internal echo, and characteristics such as microcalcification, the patients were divided into the PTC metastasis group (n = 55) and the PTC group (n = 95). The detection rate of ultrasound imaging combined with serum indicators and the invasiveness of PTC were observed and analyzed. Results: The detection rate of ultrasound imaging combined with serum indicators in both groups was significantly better than that of ultrasound imaging and serum indicators (P < 0.05). The detection rate of ultrasound imaging combined with serum indicators was compared between the groups. The removal rate of the PTC metastasis group was significantly better than that of the PTC group (P < 0.05). The levels of thyroid-stimulating hormone (TSH), thyroglobulin (Tg), thyroglobulin antibodies (TgAb), and thyroid autoantibodies (TPOAb) in the PTC group were lower than those of the PTC metastasis group (P < 0.05). Conclusion: Ultrasound imaging combined with serum indicators like TSH, Tg, TgAb, and TPOAb has important clinical significance in evaluating the invasiveness of PTC.
References
Wang B, Ma Y, Mou Y, et al., 2023, Predictive Value of Thyroid Transcription Factor-1 Expression Combined with Ultrasound Examination for The Invasiveness of Papillary Thyroid Cancer. Chinese Journal of Integrated Traditional Chinese and Western Medicine Imaging, 21(4): 402–406.
He C, Xu Y, Li H, 2023, Diagnostic Value of Ultrasound for Papillary Thyroid Cancer and Correlation Analysis with Microvessel Density and Tumor Invasiveness. Journal of Practical Cancer, 38(6): 937–940.
Wu P, 2023, Expression and Significance of Gal-1 And E-Cadherin in Lymph Node Metastasis of Papillary Thyroid Carcinoma, dissertation, Changchun University of Traditional Chinese Medicine.
Li S, 2023, Predictive Value of Multi-Modal Ultrasound and Radiomics for Cervical Lymph Node Metastasis of Papillary Thyroid Cancer, dissertation, Qingdao University.
Qi X, He Y, Luo X, et al., 2023, ZOOMit-IVIM-DWI Combined with Ultrasound Elastography to Predict the Invasiveness of Papillary Thyroid Cancer. Radiology Practice, 2023, 38(4): 412–418.
Zhu T, Ling K, Liu B, 2022, Research Progress on Serum Predictive Indicators of Cervical Lymph Node Metastasis in Papillary Thyroid Cancer. Shandong Medicine, 62(26): 89–93.
Zhu L, Yan J, Wang J, et al., 2022, Predicting the Invasiveness of Papillary Thyroid Cancer Based on Clinical, Ultrasound, and Genetic Characteristic Nomograms. Chinese Interventional Imaging and Therapeutics, 19(6): 356– 360.
Zhang X, Deng W, Zhang Y, 2022, Progress in the Application of Ultrasound Imaging to Evaluate the Invasiveness of Papillary Thyroid Cancer. Chinese Journal of Medical Imaging, 2022, 30(3): 287–290.
Guo X, Yang L, Fan M, et al., 2022, The Value of Ultrasound Examination Indicators for Predicting the Invasiveness of Thyroid Micropapillary Carcinoma. Journal of Medical Imaging, 32(2): 346–349.
Zheng H, Ren Y, Wang X, et al., 2021, In Different Parts, The Ultrasound Diagnostic Value of Aspect Ratio for Papillary Thyroid Cancer. Chinese Journal of Ultrasound in Medicine, 37(7): 737–740.
Wang D, Ren L, Li T, et al., 2021, Expression and Clinical Significance of S100A14 and LOXL2 in Papillary Thyroid Carcinoma Tissue. Cancer Prevention and Treatment Research, 48 (6): 594–599.
Li S, Wu L, Fu H, et al., 2020, Expression and Clinical Significance of Microrna-126 and Microrna-613 in Papillary Thyroid Carcinoma. Journal of Practical Oncology, 35(5): 430–435.
Xu J, Zhang S, Zhang Y, et al., 2020, Relationship Between Ki-67, BRAF, Galectin-3 Expression, and Lymph Node Metastasis in Papillary Thyroid Carcinoma. Modern Chinese Doctors, 58(2): 27–30.
Zhao Y, Huang J, Sun J, et al., 2019, The Relationship Between Preoperative NLR, PLR, SII, and Clinicopathological Characteristics of Papillary Thyroid Carcinoma. Chinese General Medicine, 17(5): 716–719 + 737.
Zhu M, Wang H, Zhang Y, et al., 2018, Analysis of Clinicopathological Characteristics of Papillary Thyroid Carcinoma Combined with Chronic Lymphocytic Thyroiditis. Chinese Journal of Basic and Clinical General Surgery, 25(3): 307–311.