Keywords
Metronidazole ester suppository
Fuzhiqing ointment
Wound granulation health
Blood in the stool
Submitted : 2023-11-26
Accepted : 2023-12-11
Published : 2023-12-26
Abstract
Objective: To assess the efficacy of the combined application of indometacin, furazolidone, and cuscohygrinolis α-acetylbenzoacetate suppository and Fuzhiqing ointment in treating patients with anal fissures. Methods: A total of 98 patients diagnosed with anal fissures between January 2021 and December 2022 were selected as the study participants. They were randomly assigned to two groups using the random number table method. The control group received treatment with indometacin, furazolidone, and cuscohygrinolis α-acetylbenzoacetate suppository, while the observation group underwent a combination treatment involving indometacin, furazolidone, and cuscohygrinolis α-acetylbenzoacetate suppository and Fuzhiqing ointment. The two groups were compared in terms of pain level, wound bleeding, and changes in wound granulation health. Additionally, the time for symptom disappearance, improvement in anal function, and occurrence of related adverse reactions were recorded. Results: The observation group exhibited lower pain score, wound bleeding score, and wound granulation health score compared to the control group (P < 0.05). The observation group also showed shorter times for the disappearance of symptoms as well as a quicker time for complete anal fissure healing compared to the control group (P < 0.05). No relevant adverse reactions were observed in any of the patients. Conclusion:The addition of Fuzhiqing ointment to the treatment of patients with anal fissures using metronidazole ester suppositories promotes the improvement of disease symptoms and enhances the health of wound granulations. This combined treatment demonstrates a positive effect on the overall healing process of the disease, indicating a broad application value.
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