Analysis of the Clinical Efficacy of Buzhong Yiqi Decoction in the Treatment of Mild COVID-19
Download PDF (English)

DOI

10.26689/otd.v1i2.5409

Submitted : 2023-08-27
Accepted : 2023-09-11
Published : 2023-09-26

摘要

Abstract: Objective: To explore the clinical significance of Buzhong Yiqi decoction in treating patients with mild COVID-19. Methods: 88 patients with mild COVID-19 admitted to the hospital for outpatient treatment from December 2022 to July 2023 were selected as the research subjects. They were divided into two groups through random number generator. The control group was given conventional Western medicine treatment, while the observation group was given Buzhong Yiqi decoction combined treatment. The effects of the two types of treatment were compared and analyzed. Results: Before treatment, there was no difference in inflammatory indicators between the two groups (P > 0.05); after treatment, the C-reactive protein (CRP), white blood cells (WBC), and interleukin-6 (IL-6) levels of the observation group were lower than those of the control group (P < 0.05). The treatment received in the observation group was significantly more effective the treatment received in the control group (P < 0.05). There was no difference in the scores of the traditional Chinese medicine syndrome scale between the two groups before treatment (P > 0.05). The scores for fatigue, sputum, cough, and fever of the observation group after treatment were all lower than those of the control group (P < 0.05). However, there was no statistically significant difference in the incidence of adverse reactions between the two groups (> 0.05). Conclusion: Buzhong Yiqi Decoction can reduce symptoms and improve the body’s inflammatory response of patients with mild COVID-19 patients.

参考

You Y, Yan H, Wang S, et al., 2020, Chinese Medicine Treatment Strategies for Novel Coronavirus Pneumonia

(COVID-19). Drug Evaluation Research, 43(4): 613–619.

Huang H, 2020, Thoughts on COVID-19 Based on Classical Medicine. Journal of Nanjing University of Chinese

Medicine, 36(2): 152–156.

Kristi M, Jo CW, Francis AL, 2023, Mobilizing the Community to Implement Mass Coronavirus Disease-2019

Vaccination Clinics: The Power of Free and Charitable Clinics. The Nursing Clinics of North America, 58(1): 11–23.

Yang L, Xu J, Li J, 2020, Expert Consensus on Using Traditional Chinese Medicine for COVID-19 (First Edition).

Beijing Chinese Medicine, 39(07): 657–664.

Liu L, Wang N, Xu D, et al., 2022, Mechanism of Traditional Chinese Medicine Preparations in Treating COVID-19.

Chemistry of Life, 42(12): 2222–2230.

General Office of the National Health Commission, Office of the State Administration of Traditional Chinese

Medicine, 2020, Notice on the Issuance of the “Diagnosis and Treatment Plan for COVID-19 (Trial Version 6)”,

viewed August 20, 2023, http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aefc2.shtml

Zhang W, Wu Y, Zhang H, et al., 2020, Interpretation of “Shanghai Traditional Chinese Medicine Diagnosis and

Treatment Plan for Pneumonia Infected by New Coronavirus (Trial)”. Shanghai Journal of Traditional Chinese

Medicine, 54(3): 1–4.

State Administration of Traditional Chinese Medicine, 2002, Guiding Principles for Clinical Research of New

Traditional Chinese Medicines (Trial), China Medical Science and Technology Press, Beijing, 168–189.

Yin Y, Yue Z, Ding Y, et al., 2021, Based on Network Pharmacology to Explore the Mechanism of Action of Buzhong

Yiqi Decoction on the Recovery Period COVID-19. Journal of Shandong University of Traditional Chinese Medicine,

(05): 685–694.

Cai Y, Zeng M, Chen Y, 2021, Analysis of Staged Treatment of COVID-19 Based on Network Pharmacology Chinese

Medicine Compound “Three Medicines and Three Prescriptions”. World Science and Technology - Modernization of

Traditional Chinese Medicine, 23(02): 358–384.

Zou N, Yang B, He N, et al., 2020, Application of the Theory of Good and Evil in Traditional Chinese Medicine in

Preventing and Treating COVID-19. Xinjiang Traditional Chinese Medicine, 38(05): 56–60.

Xu T, Zhou X, Chen X, et al., 2020, Analysis of the Implementation and Effectiveness of Traditional Chinese

Medicine for COVID-19 in Jiangxi Province. Journal of Jiangxi University of Traditional Chinese Medicine, 32(03):

–33.

Liu H, Zhao L, Geng S, et al., 2020, Research on Treating COVID-19 by Integrating Traditional Chinese and Western Medicine. Hebei Journal of Traditional Chinese Medicine, 35(02): 55–60.

Zheng Z, Bai Z, Li C, et al., 2020, Observation on the Effect of Traditional Chinese Medicine Syndrome

Differentiation in Treating COVID-19. Communications Medicine, 34(02): 117–118.

Wei G, Zhu E, Wang X, et al., 2020, Feasibility Study on the Feasibility of Yiqi Xuanbi Decoction in Treating

Pulmonary Fibrosis Tendency After COVID-19. Journal of Shaanxi University of Traditional Chinese Medicine,

(05): 7–10 + 21.