Keywords
Laparoscopic cholecystectomy
Percutaneous transhepatic gallbladder drainage
Submitted : 2025-06-02
Accepted : 2025-06-17
Published : 2025-07-02
Abstract
Objective: To explore the therapeutic effect of laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGBD) in the treatment of acute calculous cholecystitis (ACC). Methods: A total of 50 ACC patients treated from January 2022 to January 2025 were selected as samples and randomly divided into two groups. Group A received LC after PTGBD, while Group B received LC only. Surgical indicators, inflammatory factors, liver function indicators, complications, and conversion to open surgery rates were compared between the two groups. Results: The operation time, postoperative abdominal drainage time, postoperative anal exhaust time, and hospital stay in Group A were shorter than those in Group B, and the intraoperative blood loss was lower than that in Group B (P < 0.05). The levels of procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (IL-6) in Group A were lower than those in Group B (P < 0.05). The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBiL), and amylase (AMY) in Group A were lower than those in Group B (P < 0.05). The complication rate and conversion to open surgery rate in Group A were lower than those in Group B (P < 0.05). Conclusion: LC after PTGBD for the treatment of ACC can accelerate postoperative recovery, inhibit inflammatory factors, improve liver function, and is safe and efficient.
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