Keywords
Huatan and Xiaoyu Decoction
Chronic atrophic gastritis
Precancerous gastric lesions
Submitted : 2025-03-04
Accepted : 2025-03-19
Published : 2025-04-03
Abstract
Objective: To analyze the combined effect of Sini Powder and Huatan Xiaoyu Decoction in treating whole stomach gastritis with precancerous stomach lesions. Methods: 138 patients with whole stomach gastritis with precancerous lesions of the stomach admitted to the hospital from January 2021 to June 2024 were selected. According to the difference in treatment methods, they were divided into the study group (Sini Powder, Huatan Xiaoyu Decoction combined treatment) and the control group (Huatan Xiaoyu Decoction treatment), with 69 cases in each. Results: The curative effect and negative rate of Helicobacter pylori in the study group were significantly higher than those in the control group (P < 0.05); the TCM syndrome score and carcinoembryonic antigen and carbohydrate antigen 125 in the study group were lower (P < 0.05). Conclusion: The treatment of patients with whole stomach gastritis with precancerous gastric lesions can be improved by using Sini Powder combined with Huatan and Xiaoyu Decoction.
References
Li J, Chen J, Lu B, et al., 2018, Consensus on the Diagnosis and Treatment of Chronic Atrophic Gastritis With Integrated Traditional Chinese and Western Medicine (2017). Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 26(2): 121–131.
Zheng X, 2002, Guiding Principles for the Clinical Research of New Chinese Medicines: Trial Implementation, China Medical Science and Technology Press, Beijing, 113–118.
Xu X, Wei M, 2021, A Controlled Study on the Treatment of Precancerous Lesions of Gastric Cancer With Modified Huatan Xiaoyu Decoction and Conventional Western Medicine. Journal of Practical Clinical Medicine, 25(17): 92–96.
Wang J, 2023, Analysis of the Efficacy of Modified Sini Powder in the Treatment of Chronic Atrophic Gastritis. Chinese Journal of Modern Drug Application, 17(16): 144–147.
Cheng X, Li X, 2022, The Effect of Huatan Xiaoyu Decoction as an Adjuvant Treatment for Precancerous Lesions of Gastric Cancer. Inner Mongolia Journal of Traditional Chinese Medicine, 41(5): 16–18.
Peng C, Yang G, Zou Y, 2024, Network Pharmacology Study on the Prevention and Treatment of Precancerous Lesions of Gastric Cancer With Sini Powder. Clinical Journal of Traditional Chinese Medicine, 36(11): 2144–2149.
Li Y, 2024, Study on the Effect of Combined Treatment With Sini Powder and Huatan Xiaoyu Decoction in Patients With Total Gastritis and Precancerous Lesions of Gastric Cancer. Chinese Technology Journal Database Medicine, 2024(4): 121–124.
Jiang X, Li P, Yang Z, et al., 2024, Liu Fengbin’s Exploration of the Pathogenesis and Differentiation and Treatment Ideas of the “Inflammation-Cancer” Transformation of Chronic Atrophic Gastritis. Journal of Guangzhou University of Traditional Chinese Medicine, 41(7): 1880–1885.
Li M, Dang Z, Wang Y, 2024, Professor Dang Zhongqin’s Experience in Treating Chronic Atrophic Gastritis With Intestinal Metaplasia Based on “Zhongzhou Insufficiency, Stasis and Toxin Generation.” Chinese Medicine Research, 37(4): 11–14.
Zuo X, Li J, Zhu W, et al., 2023, Exploring the Clinical Treatment of Precancerous Lesions of Gastric Cancer From Syndrome Differentiation and Treatment. Journal of Liaoning University of Traditional Chinese Medicine, 25(2): 205–209.