Journal of Clinical and Nursing Research

The Impact of Digital-Intelligent Health Education on Dry Weight Management in Patients Undergoing Maintenance Hemodialysis

Yujuan Dai — Thu, 30 Oct 2025 14:40:34 +0800

Objective: To evaluate the effectiveness of digital-intelligent health education for patients undergoing maintenance hemodialysis. Methods: From December 2023 to December 2024, 82 patients undergoing maintenance hemodialysis in our hospital were selected and randomly divided into an observation group (n = 41, receiving routine health education) and a control group (n = 41, receiving digital health education). The levels of knowledge, belief, and behavior related to dry weight control, as well as changes in dry weight and complications, were compared before and after intervention. Results: After intervention, the observation group had higher scores for knowledge (40.96 ± 6.43), belief (39.11 ± 6.39), behavior (39.66 ± 5.78), and total score (119.04 ± 13.11) compared to the control group (p < 0.05). The observation group also showed better dry weight control than the control group (p < 0.05). The total incidence of complications in the observation group (4.88%, 2/41) was lower than that in the control group (21.95%, 9/41) (p < 0.05). Conclusion: The rational application of digital-intelligent health education can effectively maintain dry weight in patients undergoing maintenance hemodialysis, reduce complications, and improve patients’ knowledge, belief, and behavior levels. This approach is worthy of promotion.

The Effectiveness and Safety of Multimodal Pre-Emptive Analgesia in the Perioperative Period of Mid to Advanced Hepatocellular Carcinoma Undergoing TACE

Fri, 31 Oct 2025 09:31:47 +0800

Objective: To evaluate the analgesic effect and safety of hydromorphone hydrochloride in PCIA combined with flurbiprofen axetil and pre-emptive analgesia in patients with TACE treatment for hepatocellular carcinoma. Methods: Backward observation was made on 90 patients with advanced liver carcinoma who performed TACE treatment in the First Affiliated Hospital of Sun Yat-sen University from January 2022 to October 2023, dividing them into Group A (continuous pump injection of 6 mg hydromorphone + 50mg flurbiprofen ester as background injection for 2 ml/h, additional single injection of 3 ml/10min, 15 minutes before surgery) and Group B (intravenous injection of 50 mg flurbiprofen ester during the operation, additional injection of tramadol 100 mg intramuscular injection if necessary). Groups were compared and analyzed at different time points in surgery and post-operation time from pain level (NRS), side effects, inflammatory indexes (PCT, IL-6), satisfaction rate. Result: NRS scores at 5 time points, during operation, immediately post-surgery, 12, 24 hours post-operation, Group A were significantly lower than Group B (Group A during operation 3.0, immediate postoperation 3.0 to 24h 1.0; Group 4.0 to 24h 1.0, all P > 0.05). The rate of adverse reactions were comparable between the two groups (all P > 0.05). The amount of PCT (0.23 ng/ml vs 1.15 ng/ml) and IL-6 (54.49 pg/ml vs 233.49 pg/ml) decreased post-surgery in Group A compared to Group B, but were not statistically significant difference (P = 0.424/P = 0.502), and more patients in Group A were relieved to grade score of pain relief 4 or above (86.7% vs. 60%, P = 0.001). Conclusions: Pre-emptive analgesia treatment using PCIA of hydromorphone hydrochloride combined with flurbiprofen axetil has better analgesic effect than routine analgesic therapy in postoperative care of mid to advanced hepatocellular carcinoma TACE, has good safety, and is worth of further promotion and verifying.

Analysis of Obstructive Factors for Medical Staff to Implement Respiratory Rehabilitation Evidence Based on the Theoretical Domain Framework

Ying Gao, Junying Nie, Xiaoling Bai, Yajuan Shi, Ying Li — Fri, 31 Oct 2025 00:00:00 +0800

Objective: To explore the obstructive factors in the behavior of medical staff during the implementation of respiratory rehabilitation process, and to provide a basis for the rehabilitation management intervention of COPD. Methods: A descriptive nature research method was adopted. An interview outline was formulated based on the theoretical domain framework. From October to December 2024, 15 medical staff from the respiratory department of a tertiary hospital in Shaanxi Province were selected for semi-structured interviews. The interview data were analyzed using the Colaizzi 7-step analysis method. Result: The analysis of this study found that the obstructive factors for medical staff to implement respiratory rehabilitation include five theoretical domains. The problems are respectively the lack of knowledge about respiratory rehabilitation and insufficient training intensity, the insufficient self-recognition of implementing respiratory rehabilitation, the low awareness rate of patients and the low cooperation degree, the insufficient provision of instruments and facilities, the lack of rehabilitation training venues and respiratory rehabilitation clinics, and the lack of scientific and standardized respiratory rehabilitation management processes. Conclusion: There are many obstructive factors affecting the implementation of respiratory rehabilitation by medical staff. Clinical managers should take corresponding measures, continuously improve the rehabilitation management strategies for COPD, and promote the clinical application of the best evidence for respiratory rehabilitation.

Analysis of the Application Effect of Multi-Role Positioning Service Model in Hypertensive Patients in Health Examination Center

Pei Yue — Fri, 31 Oct 2025 10:24:45 +0800

Objective: To study the application effect of the multi-role positioning service model in hypertensive patients in the health examination center. Methods: A total of 152 hypertensive patients admitted to the hospital’s health examination center from January 2024 to January 2025 were selected as the subjects. They were randomly divided into two groups using a random number table method. The control group (76 cases) received conventional physical examination service mode, while the observation group (76 cases) adopted the multi-role positioning service model. The nurse proficiency and physical examination quality were compared between the two groups. Results: The nurse proficiency scores in the observation group were higher than those in the control group (P < 0.05). The physical examination quality scores in the observation group were higher than those in the control group (P < 0.05). Conclusion: The adoption of the multi-role positioning service model for hypertensive patients in the health examination center can improve nurse proficiency and physical examination quality.

Analysis of the Current Status and Influencing Factors of “Future Work Self-Clarity” Among Chinese Intern Nurses: A Cross-Sectional Survey

Fri, 31 Oct 2025 10:42:29 +0800

Background: The shortage of nurses in China is still a serious problem, how to improve the future work self-clarity of nursing students is very important. Objective: To evaluate the future work self-clarity among nursing students regarding their future careers and the factors influencing it. Methods: A total of 204 undergraduate nursing students from Guangzhou, Guangdong, China, were selected as participants for an online cross-sectional questionnaire survey. Results: The scores of the “Future Work Self-Clarity Scale”, Spiritual Climate Scale, and Career Calling Questionnaire for nursing students were (18.34 ± 3.64), (14.43 ± 3.77), (39.25 ± 10.45), respectively. Multiple linear regression analysis results indicated that satisfaction with clinical teachers, spiritual climate, and occupational calling were the influencing factors of future work self-clarity for intern nursing students (t = -3.230, 2.92, 4.68; all P < 0.05). Conclusion: The level of future work self-clarity among nursing students requires further improvement. Nursing managers should provide comprehensive attention and encouragement to nursing students to enhance their future work self-clarity and facilitate the construction and development of the nursing team.

The Role of the Quorum Sensing Signaling Pathway in Clinical Drug Resistance of Escherichia coli: A Review and Outlook

Chaolian Yang, Bin Hu, Chen Li — Fri, 31 Oct 2025 11:05:48 +0800

Quorum sensing (QS) represents a mechanism through which bacteria engage in communication via chemical signals, a phenomenon prevalent across diverse bacterial species. Recent investigations have elucidated that QS signaling pathways are pivotal in governing bacterial physiological processes, collective behaviors, and the emergence of drug resistance. Escherichia coli (E. coli), a prominent pathogenic bacterium, is increasingly exhibiting severe drug resistance issues, posing substantial hurdles for clinical interventions. Presently, a burgeoning body of research is exploring the connection between QS signaling pathways and the drug resistance mechanisms in E. coli, unveiling the coordinating function of QS within bacterial communities and its influence on antibiotic resistance. Despite some research advancements, the precise mechanisms underlying the QS signaling pathway remain ambiguous, and its potential applications are somewhat constrained. This article endeavors to systematically review the research progress concerning the QS signaling pathway in the context of clinical drug resistance mechanisms in E. coli, delving into its potential clinical applications and future research avenues, with the aim of offering novel insights and strategies to counteract drug resistance.

A Study on the Effect of Multimodal Nursing Intervention for Postoperative Pain in Gastrointestinal Surgery

Zuofen Qin, Dongmei Xie, Li Zhou — Fri, 31 Oct 2025 11:19:51 +0800

Objective: To explore the clinical effect of multimodal nursing intervention on postoperative pain management in patients undergoing gastrointestinal surgery. Methods: A total of 120 patients who underwent gastrointestinal surgery in our hospital from January 2023 to January 2024 were selected as the research subjects. They were randomly divided into the intervention group and the control group, with 60 cases in each group. The control group received routine postoperative care, while the intervention group received multimodal pain care intervention. The postoperative pain scores, the rate of using analgesic drugs, postoperative recovery indicators, and nursing satisfaction were compared between the two groups. Results: At 24 hours, 48 hours, and 72 hours after surgery, the VAS pain scores of the intervention group were significantly lower than those of the control group (p < 0.05); the rate of using analgesic drugs in the intervention group (25.0%) was significantly lower than that in the control group (48.3%) (p < 0.05); the first defecation time, first ambulation time, and hospital stay of the intervention group were shorter than those of the control group (p < 0.05); the nursing satisfaction of the intervention group (96.7%) was significantly higher than that of the control group (80.0%) (p < 0.05). Conclusion: Multimodal pain care intervention can effectively relieve postoperative pain in patients undergoing gastrointestinal surgery, reduce the use of analgesic drugs, promote postoperative recovery, and improve nursing satisfaction.

The Role of Stress-Related Inflammatory Mediators in Hepatocyte Injury in Fatty Liver Disease and Current Research Status

Ziqian Wei, Shan Ma — Mon, 03 Nov 2025 13:20:21 +0800

Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver disease globally, with its incidence rising annually. It can progress to cirrhosis and even hepatocellular carcinoma, posing a serious threat to human health. Stress can participate in the pathological process of NAFLD by activating inflammatory responses and regulating levels of inflammatory mediators, with hepatocyte injury being a core component of NAFLD progression. This paper focuses on three key stress-related inflammatory mediators: tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and C-reactive protein (CRP), elucidating their core mechanisms in the pathway related to stress signal, followed by inflammatory activation and hepatocyte injury respectively, and reviewing current research. Research indicates that certain inflammatory mediators can damage hepatocytes by directly inducing apoptosis or indirectly regulating metabolic disorders and fibrosis progression. However, questions regarding causal relationships, target specificity for intervention, and quantification of psychological stress remain unresolved. This paper aims to provide theoretical support for NAFLD intervention strategies targeting inflammatory mediators, clarifying future research directions to advance clinical translation.

Exploration on the Training of Geriatric Nursing Team under the Background of the Integration of Medical and Elderly Care Services

Xin Jin, Fan Li, Wenmin Lu, Genghua Sun, Feng Xu — Mon, 03 Nov 2025 13:30:58 +0800

At present, China has entered an aging society, and there is an urgent need for a large number of high-quality geriatric nursing professionals. However, the existing geriatric nursing team is difficult to meet the actual needs both in terms of quality and quantity. In this regard, under the background of the integration of medical and elderly care services, colleges and universities should strengthen the training of geriatric nursing talents. This paper conducts an in-depth analysis on the training of geriatric nursing teams under the background of the integration of medical and elderly care services, aiming to provide some references for promoting the reform of geriatric nursing talent training in colleges and universities and improving the level of geriatric nursing services in China.

Study on Evidence and Methods of Traditional Chinese Medicine Nursing for Patients with Diabetic Gastroparesis

Xiaoqian Gong — Mon, 03 Nov 2025 13:38:39 +0800

Diabetic Gastroparesis (DGP) is one of the common chronic complications of diabetes mellitus, with main clinical manifestations such as nausea, vomiting, postprandial fullness, and delayed gastric emptying. It seriously affects patients’ quality of life and nutritional status. This paper systematically sorts out the application evidence of Traditional Chinese Medicine (TCM) nursing in DGP, verifies its effectiveness from three aspects: evidence from ancient literature, modern clinical studies, and results of Meta-analyses. It also elaborates on specific nursing methods including Syndrome Differentiation-Based Nursing, characteristic technical nursing, and health guidance, analyzes the existing problems in current research, and puts forward future development directions, so as to provide a reference for the clinical promotion and standardization of TCM nursing for DGP.

Study on the Correlation between Irisin Expression and the Healing of Diabetic Skin Injury

Xuefeng Yu, Xi Jiang — Mon, 03 Nov 2025 13:49:32 +0800

A diabetic skin ulcer model was established by combining streptozotocin (STZ) administration with full-thickness skin defect surgery to evaluate the changes in irisin levels during the healing process. The experiment was divided into 2 groups, with 6 mice in each group: the normal control group and the diabetic skin injury group. Compared with the normal group, the model injury group showed a significant increase in blood glucose (p < 0.001), a significant decrease in healing rate (p < 0.001), and a significant decrease in irisin levels (p < 0.001) after 14 days. Irisin levels were positively correlated with blood glucose and positively correlated with wound healing rate. In conclusion, irisin may be a potential therapeutic target for the treatment of diabetic skin injury.

Current Situation and Prospect of Geriatric Nursing Models Under the Background of Healthy Aging

Wenmin Lu, Xin Jin, Fan Li, Feng Xu, Xiaoqian Yang — Mon, 03 Nov 2025 14:00:06 +0800

With the accelerating pace of population aging in China, various issues related to elderly care have emerged one after another, becoming a severe social problem. Especially against the backdrop of increasing economic pressure, the traditional family-based elderly care model is facing significant challenges and can hardly meet the elderly care needs. At present, the geriatric nursing models are relatively backward, which directly affects the quality of daily life, physical health and mental well-being of the elderly. Therefore, it is necessary to explore an appropriate geriatric nursing model to address the aging problem. Based on this, this paper analyzes and studies the current situation of geriatric nursing models under the background of healthy aging, providing references for relevant research and practice.

Application Effect of SECI Program in Improving Clinical Nurses’ Information Teaching Ability

Xue Li, Jiao Mi, Mengxue Chen, Yue Hu — Mon, 03 Nov 2025 14:11:27 +0800

Objective: To investigate the application effect of the SECI theoretical model-based training program in enhancing clinical nursing teachers ‘information-based teaching capabilities. Methods: A self-control study design was adopted, with 124 clinical nursing teachers from a tertiary hospital participating in the SECI training program from January 2024 to June 2025. The program was implemented through four stages: “Establishing Teacher Community (Socialization)”, “Case Teaching (Extravagant)”, “Integration of Discipline and Research (Fusion)”, and “Routine Application of Teaching (Implicit)”. Self-designed questionnaires were used to assess teachers’ information-based teaching capabilities before and after training, covering four dimensions: awareness and attitude towards information-based teaching, foundational skills, teaching practice, and professional practice. Data analysis was performed using SPSS 26.0. Results: Post-training, the total score of clinical nursing teachers’ information-based teaching capabilities increased from (53.47 ± 15.56) to (78.92 ± 12.34), showing statistically significant differences (t = 15.732, P < 0.001). Scores in all dimensions also showed significant improvements (P < 0.05). Multivariate linear regression analysis revealed that educational background (β = 0.198, P = 0.026) and professional title (β = 0.184, P = 0.040) were primary influencing factors for pre-training information-based teaching capabilities, while their impact weakened post-training. Conclusion: The training program based on SECI theory effectively enhances clinical nursing educators’ digital teaching capabilities. Its structured, spiral-up knowledge transformation process helps bridge competency gaps among teachers from diverse backgrounds, facilitates the mutual conversion and deep integration of tacit and explicit knowledge, and provides a practical new model for developing digital teaching competencies in clinical nursing education.

The Application of O-AMAS Teaching Model Combined with PBL Teaching in the Clinical Teaching of Neurocritical Care Trainee Nurses

Chen Chen, Jiao Mi — Mon, 03 Nov 2025 14:25:23 +0800

Objective: This study’s purpose is to explore the application of the O-AMAS teaching model combined with the PBL teaching method in the clinical teaching of neurocritical care trainee nurses. Methods: The nursing students who were doing internship in neurocritical care from June 2024 to September 2024 were set as the control group, and the traditional one-on-one teaching mode was adopted; From October 2024 to January 2025, the nursing students were set as the observation group and the course teaching based on the O-AMAS teaching model combined with PBL teaching was implemented. Results: The theoretical examination scores, operational assessment scores, teaching satisfaction, autonomous learning ability and clinical evaluation thinking ability of the two groups of nursing students were observed. The score of the experimental group was significantly higher than that of the control group (all P < 0.01). Conclusion: The application of the O-AMAS teaching model combined with PBL teaching in the clinical teaching of neurocritical care intern nursing students can improve the teaching effect and cultivate the autonomous learning ability and clinical evaluation thinking ability of nursing students.

The Application of Pain Care Based on CICARE Communication Model in Patients Undergoing Minimally Invasive Breast Surgery during the Day

Jiamin Li — Mon, 03 Nov 2025 14:40:31 +0800

Objective: This study aims to investigate the effects of pain care based on the CICARE communication model on perioperative pain control, anxiety, and nursing satisfaction in patients undergoing minimally invasive breast surgery during the day. Methods: Using a randomized controlled trial design, 200 patients who underwent minimally invasive breast surgery at our hospital’s day surgery center from January 2023 to June 2024 were selected and randomly divided into the experimental group and the control group, with 100 cases in each group. The control group received routine perioperative care, while the experimental group received standardized pain care based on the CICARE communication model in addition to routine care. The Visual Analogue Scale (VAS) was used to assess pain levels at 2 hours, 6 hours, and 24 hours after surgery, the State-Trait Anxiety Scale (STAI) was used to assess anxiety levels before and after the intervention, and a self-made nursing satisfaction questionnaire was used to evaluate patient satisfaction. Results: The VAS scores of the experimental group at 2 hours, 6 hours, and 24 hours after surgery [(3.2 ± 0.8) points, (2.1 ± 0.7) points, (1.2 ± 0.5) points] were significantly lower than those of the control group [(4.8 ± 1.1) points, (3.6 ± 0.9) points, (2.3 ± 0.6) points] (P < 0.01). After the intervention, the state anxiety score of the experimental group (38.5 ± 6.2) was significantly lower than that of the control group (46.8 ± 7.1) (P < 0.01). The total score of nursing satisfaction in the experimental group (94.2 ± 4.3) was significantly higher than that in the control group (82.6 ± 5.7) (P < 0.01). Conclusion: Pain care based on the CICARE communication model can effectively relieve postoperative pain in patients undergoing minimally invasive breast surgery during the day, reduce anxiety, and improve nursing satisfaction. It is worthy of promotion and application in day surgery care.

Research on the Application of In-situ Simulation Teaching Method Based on the Concept of Ideological and Political Education in Curriculum in the First Aid Skills of Clinical Practice Nursing Students

Meng Wang, Lichao Xing — Mon, 03 Nov 2025 14:51:00 +0800

Objective: To explore the application effect of in-situ simulation teaching method based on the concept of ideological and political education in the first aid skills training of clinical practice nursing students. Methods: A randomized controlled trial was used to select 220 trainee nurses from a hospital in 2024 and randomly divided them into the experimental group (n = 110) and the control group (n = 110). The control group adopted the traditional theory teaching + skill operation demonstration teaching method, while the experimental group implemented the in-situ simulation teaching plan integrating the ideological and political concepts of the curriculum on the basis of the traditional teaching. The scores of the first aid skills operation assessment, the Chinese version of the Jefferson Empathy Scale (JSE-NS), the Nursing Student Professional Identity Scale, and the Humanistic Care Ability Scale (CAI) were compared between the two groups after the intervention. Results: After the intervention, the scores of the first aid skills operation assessment, the total score of JSE-NS and each dimension, the total score of professional identity, and the total score of CAI and each dimension of the nursing students in the experimental group were significantly higher than those in the control group, and the differences were statistically significant (P < 0.05). Conclusion: The in-situ simulation teaching method based on the concept of ideological and political education in the curriculum can effectively enhance the first aid skills level, empathy ability, professional identity and humanistic care ability of trainee nurses, and is an effective way to achieve the deep integration of first aid skills training and ideological and political education.

Research on the Impact of the Early Rehabilitation Management Model Based on Efficacy Linkage on Functional Recovery of Patients After Cerebral Hemorrhage Surgery

Ting Yin — Mon, 03 Nov 2025 15:02:02 +0800

Objective: To investigate the effects of performance-linked early rehabilitation management model on the recovery of neurological function, motor function and activities of daily living in patients after intracerebral hemorrhage surgery. Methods: A randomized controlled trial design was adopted. A total of 120 patients after cerebral hemorrhage surgery admitted to our hospital from June 2023 to June 2024 were selected as the research subjects and were randomly divided into the experimental group and the control group, with 60 cases in each group according to the random number table method. The control group received routine postoperative care and rehabilitation guidance in neurosurgery, while the experimental group implemented an efficacy linkage early rehabilitation management model on the basis of routine care. Before the intervention, 4 weeks after the intervention, and 12 weeks after the intervention, the National Institutes of Health Stroke Scale (NIHSS), the Fugl-Meyer Assessment of Motor Function (FMA), and the Barthel Index (BI) were used to assess the degree of neurological deficits, motor function, and activities of daily living in patients, respectively. Results: After 4 weeks and 12 weeks of intervention, the NIHSS scores of the experimental group [(8.5 ± 2.1) points, (5.2 ± 1.8) points] were significantly lower than those of the control group [(10.8 ± 2.4) points, (7.9 ± 2.2) points] (P < 0.01); FMA scores [(58.4 ± 10.2) points, (78.6 ± 12.4) points] and BI scores [(55.3 ± 11.5) points, (72.8 ± 13.2) points] were significantly higher than those of the control group [(45.2 ± 9.8) points, (62.3 ± 11.7) points; (42.1 ± 10.6) points, (58.4 ± 12.5) points] (P < 0.01). Conclusion: The performance-linked early rehabilitation management model can effectively promote the recovery of neurological and motor functions in patients after cerebral hemorrhage surgery and significantly improve their ability to take care of themselves in daily living. It is an efficient rehabilitation management strategy.

Approaches to Achieving Effective Pre-Study for Systematic Anatomy

Qing Li, Yuan Xia, Lili Sun, Fengyi Zhang — Mon, 03 Nov 2025 15:13:03 +0800

In the vast field of medical education, systematic anatomy serves as a solid cornerstone, firmly supporting medical students in their journey towards clinical professional knowledge. It is not just a course but also a key to unlocking the mysteries of medicine. This course is as rich as a vast treasure trove of knowledge, covering the fine structures and functions of various human body systems. Each knowledge point is like a bright pearl in the treasure trove. It is the foundation of clinical professional courses. Many subsequent clinical courses, such as diagnostics and surgery, rely on the basic understanding provided by systematic anatomy. Its professional vocabulary is also an important source of medical field terminologies, acting as the root of medical language and constructing the entire edifice of medical communication. Although the vocabulary of this course is rich, it is not complex. It is like a set of orderly-arranged jigsaw puzzles. As long as the correct methods are mastered, it is easy to piece them together. However, in the current teaching environment, the traditional cramming-style teaching method is like an old-fashioned carriage, showing obvious disadvantages on the road of the times. The pre-study link is like a rehearsal for a wonderful performance, having a direct and crucial impact on students’ listening efficiency in class. Nevertheless, such an important teaching link is often overlooked, like a precious treasure forgotten in the corner. High-quality pre-study, for lecturers, is like giving wings to classroom teaching, which can greatly improve the efficiency of classroom teaching and make the teaching process smoother and more efficient. For students, it is like a magnifying glass that can deepen their understanding of knowledge points and their impression of the text, making the knowledge more clearly engraved in their minds. This article will focus on exploring the methods to achieve effective pre-study for systematic anatomy, hoping to contribute to the development of medical education.

Study on the Effects of Respiratory Exercise Rehabilitation Nursing on Self-care Ability, Lung Function, and Quality of Life in Patients with COPD

Yaran Li, Xinyi Ye, Hao Zhang, Wei Yuan, Jing Wang , Kunqian Liu — Mon, 03 Nov 2025 17:24:41 +0800

Objective: To explore the effects of respiratory exercise rehabilitation nursing on self-care ability, lung function, and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 88 patients with COPD admitted from February 2024 to February 2025 were selected and randomly divided into an experimental group and a control group, with 44 patients in each group. The control group received routine nursing, while the experimental group received respiratory exercise rehabilitation nursing on the basis of routine nursing. After 12 weeks of intervention, the self-care ability, lung function, and quality of life of the two groups were compared. Results: After the intervention, the scores of each dimension and the total score of self-care ability in the experimental group were significantly higher than those in the control group (p < 0.001). The improvement of lung function indicators such as FEV₁, FVC, and FEV₁/FVC in the experimental group was better than that in the control group (p < 0.001). The scores of each dimension and the total score of quality of life in the experimental group were significantly lower than those in the control group (p < 0.001). Conclusion: Respiratory exercise rehabilitation nursing can effectively improve the self-care ability, lung function, and quality of life of patients with COPD, which is worthy of clinical promotion and application.

Evaluation of the Application Effect of Nursing Risk Management in Preventing Falls among Inpatients

Thu, 06 Nov 2025 14:25:38 +0800

Objective: To evaluate the practical application effect of nursing risk management in preventing falls among inpatients, and to provide a reference for optimizing clinical safety management strategies for inpatients. Methods: A total of 428 inpatients in our hospital from January 2021 to December 2023 were selected as the research objects. They were divided into a control group (218 cases) and a study group (210 cases) according to the nursing management method. The control group received routine fall prevention nursing, while the study group implemented systematic nursing risk management. The fall rate and post-fall injury rate during hospitalization were compared between the two groups. Results: The fall rate of the study group was significantly lower than that of the control group, and the difference was statistically significant (p < 0.05). Conclusion: Nursing risk management can effectively reduce the fall rate and post-fall injury rate of inpatients through systematic risk identification, targeted intervention and continuous quality improvement. It also improves patients’ awareness of fall prevention and nursing satisfaction, and promotes the improvement of nurses’ risk management ability, which has important clinical promotion value.

The Application of TCM’s “Preventive Treatment of Diseases” Concept in Daily Hospital Infection Management

Qun Liang — Thu, 06 Nov 2025 00:00:00 +0800

With the development and popularization of modern medicine, the importance of daily hospital infection management has been continuously enhanced, making it a key approach to improving hospital safety standards and safeguarding patients’ lives. This paper explores the core connotation of the “Preventive Treatment of Diseases” concept in Traditional Chinese Medicine (TCM) and integrates it into the practice of modern hospital infection management. On one hand, it analyzes the current dilemmas in daily hospital infection management from dimensions such as frequent personnel flow, difficulties in disinfection and isolation, risks of antimicrobial abuse, and limited awareness of medical staff. On the other hand, it proposes the application scope of TCM’s “Preventive Treatment of Diseases” concept from aspects including preventive culture, environmental infection control, early warning mechanisms, and health education. Based on this, a more forward-looking, systematic, and humanistic hospital infection management system is constructed to achieve the transformation from passive response to active intervention.

Application Effect of PBL Teaching Method Based on Situational Simulation Videos in Undergraduate Teaching of Internal Medicine

Wenwen Li, Dexuan Chen, Xiong Ye, Zhirong Mao — Thu, 06 Nov 2025 14:45:48 +0800

Objective: To explore the application effect of Problem-Based Learning (PBL) teaching method based on situational simulation videos in undergraduate teaching of internal medicine, and to provide practical basis for optimizing the undergraduate teaching mode of internal medicine and improving teaching quality. Methods: A total of 32 undergraduate students majoring in clinical medicine (Grade 2021) from Shanghai University of Medicine & Health Sciences were selected as the research subjects. They were divided into an experimental group and a control group by random number table method, with 16 students in each group. The control group adopted the traditional PBL teaching method, while the experimental group used the PBL teaching method based on situational simulation videos. After the teaching, the mastery of theoretical knowledge of students in the two groups was evaluated by examinations; a questionnaire survey was conducted to assess students’ self-perceived improvement in clinical thinking, learning interest, self-directed learning ability and teamwork ability; statistical methods were used to analyze the data. Results: The scores of theoretical knowledge examination of students in the experimental group were significantly higher than those in the control group, and the difference was statistically significant (p < 0.05). In terms of self-evaluation, the experimental group showed better performance than the control group in the cultivation of clinical thinking, learning interest and self-directed learning ability, with statistically significant differences (p < 0.05); however, there was no statistically significant difference in the self-evaluation of teamwork ability between the two groups (p > 0.05). Conclusion: The PBL teaching method based on situational simulation videos can effectively improve students’ level of theoretical knowledge, enhance their clinical thinking, learning interest and self-directed learning ability in undergraduate teaching of internal medicine, and is worthy of further promotion and application in undergraduate teaching of internal medicine.

Existing Problems and Countermeasures in Hospital Public Health Management

Licai Wang — Thu, 06 Nov 2025 00:00:00 +0800

At the current stage, China’s medical and health industry is constantly developing, and it is essential to fully attach importance to the core role of Centers for Disease Control and Prevention (CDC). For tertiary hospitals, one of their key work tasks is to carry out public health management. Based on this, this paper mainly expounds on some basic problems existing in the public health management of state-owned hospitals at the current stage, and puts forward corresponding countermeasures for the identified problems. These countermeasures include enhancing the emphasis on public health management, strengthening the intensity of medical management, effectively improving the allocation of medical management resources, and intensifying the training of relevant personnel. This paper aims to provide references for improving the level of hospital public health management.

Co-infection of Tropheryma Whipplei and Mycobacterium tuberculosis in 39 Cases: A Case Series Study

Thu, 06 Nov 2025 15:10:07 +0800

Background: Whipple’s Disease (WD) is a chronic and recurrent multisystem disease caused by Tropheryma whipplei (TW). Typically, MTB infection compromises the immune system. However, clinical reports of MTB and TW co-infection are rare. Methods: This study retrospectively analyzed the admission symptoms and biochemical test results of 39 patients co-infected with MTB and TW between January 1, 2023, and August 31, 2024, at the Infectious Disease Hospital of Heilongjiang Province, China. This study further compared the admission indicators between individuals with co-infections involving more than two pathogens (multi-infected) and those infected with only MTB and TW (Co-Infected). Results: The hospitalized patients had a median age of 50 (39–58) years. Most of the patients were male (69.23%, 27/39). Most patients presented with cough (87.18%, 34/39), sputum production (76.92%, 30/39), shortness of breath (64.10%, 25/39), and reduced appetite or even anorexia (53.85%, 21/39). However, fever (41.03%, 14/39) and fatigue (41.03%, 16/39) were less common. Among the patients who underwent these four biochemical tests, the majority (86.36%, 19/22) had an A/G ratio below the normal range at the time of admission, primarily due to an increase in serum globulin levels. Multi-Infected group had higher levels of alanine aminotransferase than the Co-Infected group (17 vs. 10, p = 0.035), and aspartate aminotransferase is also higher in the multi-infected group compared to the Co-Infected group (20 vs. 14, p = 0.034). Conclusion: This is the first study to report the coinfection of Tropheryma whipplei (TW) and Mycobacterium tuberculosis (MTB) in Heilongjiang Province, China. However, this study did not find significant differences from descriptions in existing literature. Therefore, this study has provided a descriptive analysis to serve as a reference for further understanding TW infections.

Exploration of a Comprehensive Service Pathway for AI-Assisted Rational Clinical Use of Western Medicines

Wenjing Bao — Thu, 06 Nov 2025 15:18:47 +0800

Objective: To analyze the application value of artificial intelligence (AI) in the comprehensive service pathway for rational clinical use of western medicines. Methods: A sample of 73 patients undergoing western medicine treatment from December 2024 to March 2025 was selected and divided into groups by lottery. Group A received AI-assisted management for rational clinical use of western medicines, while Group B received conventional management. Thirty-six patients taking oral western medicines were included in Group B. Results: Group A outperformed Group B in terms of the irrationality rate of western medicine usage, drug management scores, adverse reaction rates, complaint rates, and satisfaction levels, with p < 0.05. Conclusion: AI-assisted rational clinical use of western medicines enhances drug management quality, reduces the irrationality rate of medication usage, and decreases complaint rates related to western medicine usage.

Analysis of The Relationship between Psychological Status of Caregivers of Parkinson’s Patients and Gender

Yanyan Bai, Jiangfang Miao — Thu, 06 Nov 2025 15:33:09 +0800

Objective: Understand the level of anxiety and depression of PD caregivers, and pay attention to the relationship between mental health and different genders. Methods: 200 PD patients and their caregivers were recruited. The Hamilton Anxiety Scale (HAMA) and the 17-item Hamilton Depression Scale (HAMD) were used to assess the anxiety and depression of the patients; The Mental Component Summary scale (MCS) of the SF-36 was used to test the mental health status of PD caregivers. Results: The PD caregivers HAMA detection of anxiety was 59 cases (29.5%), including 44 female caregivers and 15 males anxious; the PD caregivers HAMD detection of depression was 96 cases (48.0%), including 66 female caregivers and 30 male caregivers; the MCS score of PD male caregivers was 47 (42.75–52.25), and the MCS score of PD female caregivers was 41 (39–48). There were statistically significant differences in anxiety, depression and mental health scores among caregivers of different genders (p < 0.05). Conclusion: The anxiety, depression and mental health of PD female caregivers were worse than male caregivers. Clinical and social work need to pay more attention to the caregivers with mental health.

Regulation of Hemodynamic Stability in Urological Stone Patients During General Anesthesia Recovery Period Through Thermal Insulation Nursing Based on Temperature Intervention

Ying Chen — Thu, 06 Nov 2025 15:43:40 +0800

Objective: This study primarily analyzes the effectiveness of thermal insulation nursing (empowered by temperature intervention) in urological stone patients during the general anesthesia recovery period. Methods: A total of 76 urological stone patients who underwent surgical treatment as the preferred option were selected as the research subjects. The earliest consultation time was May 2024, and the latest was May 2025. The patients were randomly divided into two groups using the random number table method, namely the observation group and the control group, with 38 patients in each group. The intervention indicators of the patients were compared. Results: The overall satisfaction rate in the observation group was higher than that in the control group, and the incidence of adverse reactions was lower, with p < 0.05. At 0.5 hours, 1 hour after surgery, and at the end of surgery, the body temperature in the observation group was significantly different from that in the control group, with p < 0.05. Postoperatively, various hemodynamic indicators in the observation group were significantly different from those in the control group, with p < 0.05. The time to clench the first upon verbal command, the time to open the eyes upon verbal command, the extubating time, and the recovery retention time in the observation group were all shorter than those in the control group, with p < 0.05. Postoperative stress indicators and agitation scores at different time points in the observation group were significantly different from those in the control group, with p < 0.05. Conclusion: For urological stone patients during the general anesthesia recovery period, actively implementing thermal insulation nursing combined with temperature intervention not only enhances hemodynamic stability but also effectively reduces the risk of adverse reactions such as hypothermia and shivering. It optimizes the recovery condition, significantly improves the stress state, and increases nursing satisfaction.

Effect of MDT-Oriented CBL Model in Teaching Nursing Students in Cardiology

Qin Hu — Thu, 06 Nov 2025 15:52:21 +0800

Objective: To investigate the impact of MDT-oriented CBL model on teaching for cardiac nursing interns. Methods: A convenience sampling study was conducted with 100 cardiac nursing interns from September 2023 to June 2024 as subjects. The cohort was divided into two groups: 50 interns (control group, traditional teaching method) from September 2023 to January 2024, and 50 interns (experimental group, MDT-oriented CBL model) from February 2024 to June 2024. Comparative analyses were performed on theoretical assessments, practical skill evaluations, and teaching satisfaction. Results: The experimental group demonstrated higher scores in both theoretical and practical knowledge assessments (p < 0.05) compared to the control group. The experimental group also scored higher in all skill assessment categories (communication, teamwork, emergency response, medical history acquisition, organizational skills, humanistic care, and clinical competence) (p < 0.05). Satisfaction ratings for teaching objectives, content, methods, process, and outcomes were significantly higher in the experimental group (p < 0.05). Conclusion: Implementing the MDT-oriented CBL model in cardiac nursing education significantly improves interns’ theoretical and practical knowledge assessment scores, enhances nursing skills, and increases teaching satisfaction. This teaching model demonstrates significant potential for widespread application.

Research on the Path to Improving Humanistic Literacy of Operating Room Nursing Students–Application and Practice of the ORTCC Model

Feng Ren — Thu, 06 Nov 2025 00:00:00 +0800

Objective: To explore the application effect of the path for improving humanistic literacy of operating room nursing students based on the ORTCC model, in order to make up for the deficiency of systematic humanistic education in the traditional teaching model. Methods: 120 nursing students who practiced in the operating room from June 2023 to June 2024 were randomly divided into the experimental group and the control group, with 60 students in each group. The control group received routine teaching, while the experimental group applied the ORTCC model on the basis of routine and intervened through setting humanistic literacy goals, formulating behavioral norms, conducting diversified training, implementing two-way assessment, and creating departmental culture. The effect of the intervention was evaluated using the Nurse Humanistic Quality Scale, the Clinical Communication Ability Assessment Scale for Operating Room Nursing Students, and a self-made nursing satisfaction questionnaire. Results: After the intervention, the total score of humanistic literacy in the experimental group (4 weeks of intervention: 161.43 ± 10.06 points, 12 weeks of intervention: 165.71 ± 9.45 points) was significantly higher than that in the control group (139.38 ± 10.95 points, 143.31 ± 10.52 points) (all p < 0.001); The total score of clinical communication ability in the experimental group (109.69 ± 8.05 points for 4 weeks of intervention, 116.90 ± 7.21 points for 12 weeks of intervention) was also significantly better than that in the control group (99.14 ± 9.23 points, 103.03 ± 8.78 points) (all p < 0.001); The total score of patient care satisfaction in the experimental group (94.2 ± 4.3) was significantly higher than that in the control group (82.6 ± 5.7) (p < 0.001). Conclusion: The ORTCC model can systematically enhance the humanistic literacy, clinical communication skills and patient satisfaction of operating room nursing students, providing an effective approach for optimizing clinical teaching in the operating room.

Test and Application Prospect of Tracheal Stent in Vitro and in Vivo

Longhu Hu, Anning Li — Thu, 06 Nov 2025 16:16:42 +0800

The development and improvement of tracheal stents, as an effective treatment for respiratory diseases such as tracheal stenosis and tracheal collapse, has been a hot topic in the field of medical engineering. In vitro testing and animal experiments are key steps in evaluating the performance and safety of tracheal stents. This paper reviews the in vitro testing methods, animal experimental models, current research status, and future directions of tracheal stents, aiming to provide research directions for the development and in vitro and in vivo testing of tracheal stents.

Application of Traditional Chinese Medicine Hot Compress Package Combined with Kinesio Taping in Postoperative Nursing of Total Knee Arthroplasty

Dan Xiao, Qiujin Hao, Yana He, Ran An, Xiaoqing Zhang — Thu, 06 Nov 2025 16:47:37 +0800

Objective: To explore the application of external application of Traditional Chinese Medicine (TCM) hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty. Methods: Ninety patients with severe knee osteoarthritis who underwent total knee arthroplasty in our department from January to December 2022 were randomly divided into two groups using a random number table method: one group was named the conventional group (n=45), which received the standard orthopedic nursing process throughout, including basic pain management, incision care, and functional exercise guidance; the other group was defined as the experimental group (n=45), which, in addition to the conventional nursing framework, incorporated the local transdermal drug delivery technique of TCM hot compress package and the biomechanical correction scheme of Kinesio Taping for collaborative intervention. Finally, the differences in postoperative resting/active pain scores (VAS) of the affected limb and satisfaction with nursing services between the two groups were compared using quantitative assessment tools. Results: The satisfaction with nursing care in the conventional group was significantly lower than that in the experimental group (P < 0.05); the VAS score after nursing in the conventional group was significantly higher than that in the experimental group (P < 0.05). Conclusion: The application of external application of TCM hot compress package combined with Kinesio Taping in postoperative nursing of total knee arthroplasty has a definite effect, reducing pain and improving patient satisfaction with nursing services.

Aromatherapy Combined with Emotional Freedom Techniques on Fear of Recurrence and Sleep Quality in Lung Cancer Survivors

Haiying Xu, Wei Xiao — Thu, 06 Nov 2025 16:54:19 +0800

Objective: This study aimed to explore the effect of aromatherapy combined with emotional release technology on recurrence fear and sleep quality of lung cancer survivors. Methods: 114 cases of lung cancer survivors were divided into routine nursing group, emotional release technology group and aromatherapy combined with emotional release technology group. Routine nursing group received routine nursing; Emotional release technology group implemented emotional release technology for one month on the basis of routine nursing group; Aromatherapy combined with emotional release technology group used lavender aromatherapy on the basis of emotional release technology group. Results: After one month of intervention, there were statistically significant differences in the scores of fear of disease progression and sleep quality among the three groups. Conclusion: Aromatherapy combined with emotional release technology can improve the sleep quality of lung cancer survivors and reduce the economic toxicity of cancer to some extent.

The Impact of IKAP-Based Nursing Interventions on the Caregiving Capacity of Family Carers for Individuals with Dementia

Shuhui Zhao, Yao Li — Mon, 10 Nov 2025 09:20:29 +0800

Objective: To investigate the effect of an information-knowledge-attitude-practice (IKAP) nursing intervention on the caregiving capacity of family caregivers of elderly dementia patients. Methods: Sixty-nine family caregivers of elderly dementia patients attending the neurology outpatient clinic of a hospital between October 2024 and March 2025 were selected. They were randomly divided into a control group (n = 35) and an observation group (n = 34). The control group received routine health education, while the observation group additionally underwent a systematic Information-Knowledge-Attitude-Practice (IKAP) nursing intervention. Care competence and self-efficacy scores were compared between groups before intervention and after 12 weeks. Results: Pre-intervention, no statistically significant difference existed in care competence or self-efficacy scores between groups (p > 0.05). Following the 12-week intervention, all scores significantly increased in both groups, with the observation group demonstrating superior outcomes compared to the control group (p < 0.001). Conclusion: The care intervention program based on the IKAP model effectively enhances caregivers’ care competence and self-efficacy, thereby positively promoting the quality of life for patients with dementia.

The Mediating Effect of Pain on the Relationship between Sleep Quality and Health-Related Quality of Life among Elderly Patients with Chronic Diseases: An Empirical Analysis Based on CHARLS Data

Mon, 10 Nov 2025 09:31:59 +0800

Abstract:Objective:To explore the mediating effect of pain between sleep quality and health-related quality of life in elderly patients with chronic diseases. Methods: Based on the 2018 China Health and Aging Tracking Survey (CHARLS) data, 3,284 elderly patients with chronic diseases aged 60 or above were selected as the research subjects. The sleep quality, pain status, health-related quality of life, and demographic-related data of these elderly patients were obtained. Pearson correlation analysis was used to explore the correlations among the variables; linear regression models and Bootstrap repeated sampling method were used to analyze the mediating effect of pain between sleep quality and health-related quality of life. Results: Sleep quality was positively correlated with health-related quality of life (r=0.218,P<0.001), and pain was negatively correlated with sleep quality and health-related quality of life (r=-0.496, -0.067, P<0.001). The mediating effect results showed that pain played a partial mediating role between sleep quality and health-related quality of life in elderly patients with chronic diseases (effect value=0.049), and the mediating effect accounted for 23.33%. Conclusion: Pain is a mediating variable between sleep quality and health-related quality of life in elderly patients with chronic diseases. This suggests that clinical practice should incorporate pain assessment into the routine management of elderly patients with sleep disorders and chronic diseases. By alleviating pain, sleep quality can be improved, and subsequently, their health-related quality of life can be enhanced.

Comprehensive Review and Response Strategies for Nipple Confusion

Chong Yang, Jie Cui, Yongtao Kang, Longhai Song — Mon, 10 Nov 2025 09:42:09 +0800

The term “nipple confusion” accurately describes the confusion newborns experience between their mother’s nipple and an artificial nipple during feeding. Specifically, it refers to the feeding habits infants develop based on their initial feeding experiences after birth. Infants accustomed to the maternal nipple often resist bottle-feeding; conversely, those accustomed to bottle-feeding may reject the maternal nipple. This confusion is particularly common among infants receiving mixed feeding.

Evaluation of the Efficacy of Flat Mesh Tension-Free Hernioplasty in the Treatment of Inguinal Hernia

Haibo Zhang — Mon, 10 Nov 2025 09:52:58 +0800

Objective: To explore and analyze the clinical efficacy of flat mesh tension-free hernioplasty in the treatment of patients with inguinal hernia. Methods: A total of 60 patients with inguinal hernia were included and equally divided into an observation group (30 cases, flat mesh tension-free hernioplasty) and a control group (30 cases, mesh plug tension-free hernioplasty) based on differences in surgical plans. The visual analog scale (VAS) for postoperative pain, inflammatory markers (C-reactive protein, white blood cell count), and complication rates were compared between the two groups. Results: At 24 and 48 hours postoperatively, the VAS scores in the observation group were significantly lower than those in the control group (P < 0.05). At 24 hours postoperatively, the levels of CRP and WBC were also lower in the observation group (P < 0.05). The complication rate was slightly lower in the observation group (P > 0.05). Conclusion: Flat mesh tension-free hernioplasty for inguinal hernia can alleviate postoperative pain and suppress inflammatory responses, with fewer complications, making it suitable for promotion at primary healthcare facilities.

A study on the application effect of the joint rehabilitation intervention based on the hospital-community-family model for middle-aged and elderly patients with chronic kidney disease

Mon, 10 Nov 2025 10:19:40 +0800

Objective: To explore the application effect of the hospital-community-family model-based combined rehabilitation exercise intervention on middle-aged and elderly patients with chronic kidney disease. Methods: Using the convenience sampling method, 80 patients in the stable stage of CKD who were treated in the nephrology department of a tertiary hospital from May 2022 to June 2023 were selected as the research subjects. They were divided into the experimental group (40 cases) and the control group (40 cases) by random number table method. The control group received conventional exercise intervention plus telephone follow-up, while the experimental group received combined hospital-community-family model-based exercise intervention in addition to the control group, using remote medical guidance and monitoring of the application effect of exercise rehabilitation on middle-aged and elderly patients with chronic kidney disease. The glomerular filtration rate, 6-minute walking distance, fatigue and social support scores of the two groups of patients were measured before the intervention, 4 weeks after the intervention, and 12 weeks after the intervention. Results: Before the intervention, there were no statistically significant differences in glomerular filtration rate, 6-minute walking distance, fatigue and social support scores between the two groups (P>0.05). After 12 weeks of intervention, the glomerular filtration rate, 6-minute walking distance and social support scores of the experimental group were higher than those of the control group; the differences were statistically significant (P < 0.05). The behavioral, emotional, sensory and cognitive scores of the Piper-Fatigue Revised Scale of the experimental group were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion: Based on the hospital-community-family model combined rehabilitation exercise, using remote medical guidance for the continuous care of middle-aged and elderly patients in the stable stage of chronic kidney disease can effectively improve the exercise endurance and social support level of patients, improve the fatigue condition, and the implementation effect is positively correlated with the intervention time.

Survey on High School Students’ Mastery of First Aid Knowledge, Training Attitudes, and Needs

Shuai Liu, Yang Bai, Mingcan Xue, Lishuo Gao — Mon, 10 Nov 2025 00:00:00 +0800

Objective: To understand high school students’ mastery of first aid knowledge and their needs for first aid training, analyze the influencing factors of their mastery of first aid knowledge, and provide a reference basis for targeted first aid training for high school students. Methods: A total of 930 high school students from three high schools in Nanchong City, Sichuan Province, were selected as the research subjects using the convenience sampling method. A self-made questionnaire was used for the survey. SPSS 25.0 software was employed for data description and analysis. Results: The average score for high school students’ mastery of first aid knowledge was (12.23 ± 4.39), with a pass rate of 29.5%. There were significant differences in the correct response rates for each question (4.62% to 92.80%). 92.9% of high school students expressed willingness to participate in first aid training. Multivariate logistic regression analysis revealed that participation in first aid training (not participating in training: OR = 2.524, 95%CI = 1.858–3.428) was an influencing factor for high school students’ mastery of first aid knowledge. Conclusion: High school students have insufficient mastery of first aid knowledge, and the correct response rates need to be improved. It is essential to enhance the popularization of first aid knowledge among high school students and implement diversified training formats and courses.

The Influence of Psychological Security on Quality of Life in Patients Undergoing Hysteroscopic Surgery–The Mediating Effect of Social Support

Surong Xu, Xiuyun Li — Mon, 10 Nov 2025 00:00:00 +0800

With the development of minimally invasive gynecological technology, hysteroscopic surgery has been widely used in the treatment of gynecological diseases due to its advantages of rapid recovery and minimal trauma. From the perspective of patients undergoing hysteroscopic surgery, this paper explores the influence of their psychological security on quality of life, analyzes the mediating effect of social support, and puts forward specific countermeasures and suggestions. The purpose is to improve the psychological security and quality of life of patients undergoing hysteroscopic surgery, and provide reference for the subsequent development of hysteroscopic surgery.

Application of MBSR Combined with Relaxation Training in the Perioperative Period of Interventional Therapy for Lumbar Disc Herniation

Dan Xiao, Qiujin Hao, Yana He, Zhixin Liu, Xiaoqing Zhang — Mon, 10 Nov 2025 00:00:00 +0800

Objective: To explore the application effect of MBSR combined with relaxation training in the perioperative period of radiofrequency ablation combined with ozone interventional therapy for lumbar disc herniation. Methods: Ninety patients with lumbar disc herniation who underwent radiofrequency ablation (RFA) combined with ozone interventional therapy in the Orthopedics and Traumatology Department of our hospital from January to December 2019 were included as research samples. They were randomly divided into two groups using a random number table method: the control group (45 cases) received routine perioperative nursing and health education; the experimental group (45 cases) received a comprehensive psychological intervention program consisting of MBSR combined with relaxation training in addition to the control group's treatment. Changes in pain perception (VAS), sleep quality (PSQI), psychological state (SAS/SDS), and life satisfaction (SWLS) were compared between the two groups before and after the intervention. Results: After the intervention, both groups showed a significant decrease in SAS and SDS scores (P<0.05), with a greater decrease in the experimental group (P<0.05); the experimental group had lower PSQI total scores and scores in each dimension compared to the control group (P<0.05); the experimental group had a significantly lower VAS score (3.56±0.88) compared to the control group (5.94±0.62) (P<0.05); the experimental group had a higher SWLS score (28.59±5.61) compared to the control group (22.46±4.15) (P<0.05). Conclusion: MBSR combined with relaxation training can significantly optimize the perioperative psychological state of patients undergoing RFA combined with ozone interventional therapy, reduce pain sensitivity and stress responses, and simultaneously improve sleep quality and treatment satisfaction.

Observation on the Effect of Dexmedetomidine in Suppressing Cough Reflex During Tracheal Extubation in Pediatric Patients Undergoing General Anesthesia

Jian Wu, Lijuan Chen, Jinwen Zeng — Mon, 10 Nov 2025 00:00:00 +0800

Objective: To investigate the suppressive effect of dexmedetomidine on the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia and its impact on vital signs. Methods: A total of 60 pediatric patients undergoing elective surgery admitted to our hospital from January to August 2025 were selected and randomly divided into an observation group and a control group, with 30 cases in each group, using a random number table method. The control group received an intravenous infusion of 0.9% sodium chloride injection 30 minutes before the end of surgery, while the observation group received an intravenous pump infusion of dexmedetomidine (1 μg/kg, diluted to 4 μg/ml with normal saline). The severity of cough (graded from 0 to 3) and vital signs, including heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse oxygen saturation (SpO₂), were recorded 5 minutes before extubation, at the time of extubation, and 5 minutes after extubation in both groups. Results: The severity of cough in the observation group was significantly milder than that in the control group (P < 0.05), with a significantly higher proportion of grade 0 cough in the observation group (23.33% vs 3.33%). At extubation and five minutes post-extubation, the observation group exhibited significantly lower HR, SBP, and DBP than the control group (P < 0.05). In contrast, SpO₂ levels remained comparable between the groups (P > 0.05). Conclusion: Dexmedetomidine can effectively suppress the cough reflex during tracheal extubation in pediatric patients undergoing general anesthesia, reduce the severity of cough, stabilize hemodynamic parameters, and has no significant impact on respiratory function, demonstrating good clinical safety.

The Impact of Progressive Effect Nutritional Care on Treatment Adherence, Quality of Life, and Nutritional Status in Uremia Patients Undergoing Dialysis

Limin Xu, Liuping Fu, Yueting Chen, Weiwei Dai, Jianmin Yao — Mon, 10 Nov 2025 00:00:00 +0800

Objective: To investigate the impact of progressive effect nutritional care on uremia patients undergoing dialysis. Methods: A total of 101 uremia patients undergoing dialysis admitted from January 2024 to March 2025 were selected as the study subjects and divided into two groups by lottery method. The control group (55 cases) received routine care, while the observation group (56 cases) received a combination of routine care and progressive effect nutritional care. Results: After 4 weeks of care, the observation group demonstrated higher treatment adherence (P < 0.05), better quality of life (P < 0.05), and improved nutritional status (P < 0.05) compared to the control group. Conclusion: Progressive effect nutritional care can significantly enhance treatment adherence, quality of life, and nutritional status in uremia patients undergoing dialysis.

Dermatomyositis: Review and Considerations in Older Adults

Xiaoqing Wu, Jingtong Wang — Mon, 10 Nov 2025 11:48:21 +0800

Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by prominent skin lesions, muscle weakness, and clinically heterogeneous systemic manifestations. Among patients with DM, the male-to-female ratio is 2:1. Juvenile dermatomyositis (JDM) is most prevalent between the ages of 4 and 14 years, while adult-onset dermatomyositis typically occurs between the ages of 40 and 60 years. In a population-based study conducted in Olmsted County, Minnesota, USA, the risk of DM was found to increase with age across different age groups stratified by decade. The incidence rate of DM in individuals aged ≥ 80 years was 3.2 per 100,000 person-years. Dermatomyositis in elderly patients is characterized by unique clinical manifestations, pathogenic mechanisms, and therapeutic approaches. However, discussions regarding geriatric dermatomyositis are currently limited. Therefore, this article aims to review the epidemiology, clinical features, histopathology, and pathogenesis of dermatomyositis, with a particular focus on the unique clinical characteristics of geriatric dermatomyositis.

Application Effect of Risk Management in Nursing Work of Fever Clinics

Xiaoyang Chen, Ye Wu — Mon, 10 Nov 2025 11:57:59 +0800

Objective: To observe the application effect of risk management in the nursing work of fever clinics, especially its effect on improving nursing satisfaction and the work quality of nursing staff, as well as reducing the incidence of nursing risk events, and to provide a scientific reference for future clinical research and practice. Methods: This study adopted a retrospective approach, fixing the research period from December 2024 to August 2025. A total of 110 patients admitted to the fever clinic of our hospital were selected as the research objects and divided into two groups (the control group and the experimental group) using the random number table method. Each group had 55 patients. Then, differentiated nursing strategies were implemented for the two groups. Both the control group and the experimental group received routine nursing. The difference was that the experimental group was additionally given risk management measures on the basis of routine nursing. After 7 days of intervention, the nursing satisfaction rate, nursing quality, cognitive score of fever clinic risks, nursing error rate, complaint rate, and incidence of risk events were compared and analyzed between the two groups. Results: The nursing satisfaction score, nursing complaint rate, incidence of nursing risk events, nursing error rate, nursing quality score, and cognitive score of fever clinic risks in the experimental group were significantly better than those in the control group. The differences were statistically significant (P < 0.05). Conclusion: Risk management has a significant application effect in the nursing work of fever clinics, playing a positive role for both patients and nursing staff. It is an effective measure to comprehensively improve nursing quality and an important means to greatly reduce the incidence of nursing risk events, thus having high clinical promotion value.

Nursing Care of a Patient with Intracranial Aneurysm Rupture and Hemorrhage Complicated by Pulmonary Embolism After Surgery

Rong Zeng, Bingying Yan, Shanshan Ge — Mon, 10 Nov 2025 12:06:31 +0800

Objective: To summarize the nursing experience of a patient with intracranial aneurysm rupture and hemorrhage who developed pulmonary embolism after clipping surgery. Methods: A patient in our hospital, who had intracranial aneurysm rupture and hemorrhage and developed pulmonary embolism after clipping surgery, was selected as the research subject. Through multidisciplinary collaboration, standardized assessment and dynamic condition observation, various risks were identified early. Combined with the patient’s individual characteristics, a personalized nursing plan was formulated. During the treatment process, emphasis was placed on strengthening the patient’s airway management, closely monitoring various indicators, and preventing postoperative complications. Targeted nursing measures were adopted: reasonable airway humidification and effective lung care were used to gradually control the patient’s pulmonary infection; fluid balance management and individualized care were implemented to ensure the patient’s normal circulating blood volume, thereby optimizing cerebral perfusion and cerebral oxygenation. Since the patient had overlapping risk factors for bleeding and thromboembolic events, evidence-based nursing principles were followed for thromboembolism prevention, and anticoagulation strategies and nursing plans were dynamically adjusted to reduce the occurrence of postoperative complications. Results: The patient’s condition improved and was successfully discharged on the 22^nd day after surgery, and then transferred to a local rehabilitation hospital for further treatment. At the 1-month follow-up after discharge, the patient recovered well; at the 3-month follow-up after discharge, the patient had recovered and returned home. Conclusion: The results show that standardized assessment and condition observation, multidisciplinary collaboration, and personalized nursing plans can significantly reduce the occurrence of postoperative complications and improve the patient’s prognosis. This nursing experience provides a reference for the nursing of similar patients in the future.

Study on a Rapid Extraction and Detection Method for 16S rRNA of Intestinal Flora

Yuanyuan Wang — Mon, 10 Nov 2025 12:14:23 +0800

This study established a rapid extraction method for the 16S rRNA gene of intestinal flora. Combined with next-generation sequencing (NGS) technology, this method can be applied to intestinal microbial ecology analysis. The fecal sample was mixed with lysis buffer, incubated at 90°C for 15 minutes, vortexed, and then centrifuged. The supernatant was collected, and specific primers were added for PCR amplification. The PCR products were purified, and index tags were established for the targets to obtain libraries. After library purification and quality inspection, the libraries could be loaded for sequencing. Under optimized conditions: when the number of PCR cycles was 25 and the initial amount of DNA for library construction was 12.5 ng, fewer chimeras were generated. The library size was 500–700 bp, and there were no primer dimers of approximately 120 bp. This method is rapid, accurate, and sensitive, and can be used for the analysis and detection of the 16S rRNA gene of intestinal flora.

Analysis of Influencing Factors and Nursing Countermeasures for Hypoglycemia in Inpatients with Diabetes Mellitus

Yun Gao — Mon, 10 Nov 2025 00:00:00 +0800

Studies have shown that the implementation of targeted nursing countermeasures can significantly reduce the incidence of hypoglycemia in inpatients with diabetes mellitus, improve patients’ quality of life, and promote the stable control of their condition. This paper conducts an in-depth analysis on the influencing factors of hypoglycemia in inpatients with diabetes mellitus and the corresponding nursing countermeasures. It expounds the main factors affecting hypoglycemia in inpatients with diabetes mellitus, and then puts forward effective nursing countermeasures. The purpose is to provide valuable references for promoting the innovative development of clinical nursing work.

Application of Tripartite Collaborative Nursing in Enhancing Resilience Among Families of Pediatric Leukemia Patients

Qinghuan Zhou, Hui Liu, Lingli Zhou, Zhoujing Hu, Xingqin Tian — Mon, 10 Nov 2025 00:00:00 +0800

Objective: To investigate the efficacy of a tripartite collaborative nursing intervention in enhancing resilience among families of pediatric leukemia patients. Methods: Based on Walsh’s family resilience theory and collaborative nursing principles, and after reviewing a large amount of literature，a tripartite intervention was constructed, which was led by the nursing team, coordinated by medical social workers, and supported by volunteers. Caregivers of pediatric hematology inpatients at a tertiary-level Class A hospital were selected as research subjects. which were divided into a control group (n = 30) and an experimental group (n = 30) according to a randomized block design. The control group are treated with standard nursing care, which included health education, counseling, and psychological support from nurses. The experimental group, in addition, was provided with a tripartite collaborative nursing intervention for 3 months. Results: The family resilience level, social support, and family function scores of the experimental group were higher than those of the control group, and the differences were statistically significant (P ≤ 0.05). Conclusion: The implementation of tripartite collaborative nursing intervention improves the resilience of families of children suffered from leukemia.

Analysis of the Application Value of the MEWS in Neurological Patients and Its Prognostic Influencing Factors

Mon, 10 Nov 2025 00:00:00 +0800

Objective: To evaluate the predictive value of Modified Early Warning Score (MEWS) for neurological disease prognosis and identify prognostic factors. Methods: This retrospective study analyzed 768 neurological patients with MEWS ≥ 4 (June 2022–June 2024). Patients were stratified by outcomes (favorable/unfavorable). Multivariable logistic regression and ROC analysis were performed. Results: 108 cases (13.1%) had unfavorable outcomes. Significant prognostic factors included: age, TBI history, onset-to-admission time, PT, MEWS score, and MEWS ≥ 4 frequency (all P < 0.05). MEWS showed AUC = 0.749 (sensitivity 62.0%, specificity 77.4%). Conclusion: MEWS demonstrates moderate predictive value (AUC = 0.749) for neurological outcomes. Consciousness assessment limitations (56.5% impaired cases) may affect sensitivity. A specialized model incorporating pupillary reflexes and GCS is recommended for improved early warning.

A Scoping Review on the Application of FAS in Postoperative Active Pain Management Among Surgical Patients in China

Yuying Hu, Yingge Tong, Huiqing Jin, Wenqian Cheng, Mengyu Xin, Ke Ni, Xiang Pan — Mon, 10 Nov 2025 14:14:40 +0800

Objective: To conduct a scoping review on the application status of the Functional Activity Score (FAS) in postoperative active pain management in China, providing a reference for its standardized and normative promotion. Methods: Computerized searches of Chinese and English databases were performed to collect studies published by Chinese scholars from 2005 to July 2025 on the application of FAS in postoperative active pain management. After strict screening, the basic characteristics, application fields, assessment models, evaluation timing, types of functional activities, and clinical outcomes of the included literature were systematically analyzed. Results: A total of 18 studies were included, involving surgical types such as thoracic surgery, general surgery, and orthopedics. All studies adopted FAS combined with the Numeric Rating Scale (NRS) for assessment, with evaluation timing mostly concentrated within 72 hours postoperatively. The selected functional activities primarily included respiration-related and limb movements. Evaluation indicators covered pain control, functional recovery, complications, adverse events, patient experience, and tool assessment, with most studies reporting positive outcomes. Conclusion: FAS can effectively enhance pain control and promote functional recovery in postoperative active pain management in China, demonstrating high clinical value. However, existing studies exhibit inconsistencies in assessment criteria, selection of activity types, and research quality.

Strategies to Overcome Challenges in Real-World Value Assessment amid Full DRG Implementation

Li Zhao, Xiaolei Liu, Xinqi Tian, Yang Liu, Xiaochun Li — Mon, 10 Nov 2025 16:54:43 +0800

Against the backdrop of the comprehensive implementation of Diagnosis-Related Groups (DRG), Real-World Value Assessment (RWVA) has become a crucial support for driving healthcare payment system reform and value-oriented decision-making. This paper systematically reviews the evolving trends in international Real-World Evidence (RWE) methodology from 2020 to 2025, analyzing its integration pathways with health economics and the development direction of dynamic value assessment models. Within the context of China’s DRG-based payment policy implementation, it explores the application bottlenecks of Real-World Data (RWD) in technology access and price negotiations, proposing optimization strategies from three dimensions: data, methodology, and policy. The study argues that high-quality, interoperable data infrastructure should be constructed, models integrating RWE and health economics should be refined, and a value-oriented payment decision-making system should be established to optimize healthcare resource allocation and enhance the scientific nature of medical insurance payments. By implementing these strategies, the study anticipates the establishment of a closed-loop mechanism linking evidence generation, value assessment, and payment decision-making, thereby improving the transparency, efficiency, and sustainability of China’s healthcare payment system. The expected outcome is a more data-driven and outcome-oriented policy framework that aligns real-world clinical performance with medical insurance value recognition.

Correlation Study between Fetal Foot Length Measured by Ultrasound and Gestational Age

Chao Huang — Tue, 11 Nov 2025 17:29:31 +0800

Objective: To explore the correlation between fetal foot length measured by ultrasound and gestational age. Methods: This study employed ultrasound to measure the fetal foot length, femoral length, and foot length/femoral length ratio in 214 pregnant women from 12 to 40 weeks of gestation, all of whom had no pregnancy complications or obstetric complications, and whose fetuses were normal. Results: A significant positive correlation was found between fetal foot length and gestational age (r = 0.967, p < 0.001); a similarly significant positive correlation was observed between fetal femoral length and gestational age (r = 0.972, p < 0.001); and a non-significant positive correlation was noted between the foot length/femoral length ratio and gestational age (r = 0.943, p < 0.001). Conclusion: Ultrasound can accurately measure fetal foot length and femoral length, both of which exhibit a significant positive correlation with gestational age, making them important reference indicators for assessing fetal growth and development.