Journal of Clinical and Nursing Research

Analysis of the Effects of Combined Spinal-Epidural Anesthesia and Epidural Anesthesia in Appendicitis Surgery at Primary Hospitals

Congjing He — Wed, 02 Jul 2025 15:24:11 +0800

Objective: To analyze the effects of combined spinal-epidural anesthesia and epidural anesthesia in patients undergoing appendicitis surgery. Methods: Seventy-eight patients who underwent surgical treatment for appendicitis from February 2022 to February 2025 were selected as samples and randomly divided into two groups. The study group received combined spinal-epidural anesthesia, while the control group received epidural anesthesia. Anesthesia indicators, vital signs, and complication indicators were compared between the two groups. Results: The onset time of anesthesia in the study group was shorter than that in the control group, the visual analog scale (VAS) score was lower than that in the control group, and the highest plane of anesthesia block was lower than that in the control group (P < 0.05). At 15 minutes after anesthesia induction and at the end of surgery, the heart rate (HR), mean arterial pressure (MAP), and blood oxygen saturation (SPO2) in the study group were significantly different from those in the control group (P < 0.05). The complication rate in the study group was lower than that in the control group (P < 0.05). Conclusion: Combined spinal-epidural anesthesia for appendicitis surgery can reduce the impact of anesthesia on vital signs, shorten the onset time of anesthesia, and is highly effective and feasible.

Analysis of the Impact of Predictive Rehabilitation Nursing Model on the Quality of Emergency Transport for Patients with Acute Cerebral Hemorrhage

Shijie Li, Tingting Dong, Yufang Zhao, Le Zhao, Zhiwei Qiu — Wed, 02 Jul 2025 15:31:46 +0800

Objective: To analyze the impact of the predictive rehabilitation nursing model on the quality of emergency transport and rehabilitation outcomes for patients with acute cerebral hemorrhage (ICH). Methods: A total of 62 patients with acute cerebral hemorrhage admitted to the hospital from January 2022 to December 2024 were selected as the study subjects. The observation group (n = 31) received conventional nursing combined with the predictive rehabilitation nursing model during the emergency process, while the control group (n = 31) received conventional nursing. The recovery conditions (Fuel-Meyer Assessment (FMA) score, Barthel Index (BI)), incidence of complications, nursing satisfaction, and time to regain consciousness were compared between the two groups. Results: After the intervention, the FMA and BI scores of the observation group were significantly higher than those of the control group, with statistically significant differences. The incidence of complications in the observation group was significantly lower than that in the control group. In terms of nursing satisfaction, the scores of various indicators in the observation group were higher than those in the control group, with statistically significant differences. The time to regain consciousness in the observation group was (48.72 ± 11.76) minutes, compared to (64.29 ± 14.58) minutes in the control group, with the observation group regaining consciousness earlier than the control group. Conclusion: The application of the predictive rehabilitation nursing model in the emergency transport process of patients with acute cerebral hemorrhage can reduce the incidence of complications, shorten the duration of consciousness disorder, improve the quality of transport, and enhance functional rehabilitation levels.

Research on Clinical Nursing Key Points and Complications Prevention Strategies after Coronary Heart Disease Stent Implantation

Tao Li — Wed, 02 Jul 2025 15:36:04 +0800

With the development of the social economy and the continuous improvement of people’s living standards, the number of coronary heart disease patients is on the rise, even affecting some younger groups. When a patient’s coronary artery stenosis endangers their life, doctors usually recommend coronary artery stent surgery to effectively improve myocardial ischemia and prevent sudden death. After a successful operation, it is necessary to clarify the key points of clinical nursing and prevent complications. Starting from the situation after coronary heart disease stent implantation, this article analyzes the key points of clinical nursing and proposes specific strategies for preventing complications, aiming to improve the surgical effect and provide a reference for complication prevention activities.

Application and Evaluation of Common Clinical Imaging Techniques in Cancer Diagnosis

Yalei Shang — Wed, 02 Jul 2025 15:39:55 +0800

With the reform and opening up entering a new era, China’s modern civilization and technology are “rolling forward”. In the medical field, innovative changes in radiology imaging technology have presented unprecedented value opportunities in tumor diagnosis. Therefore, this article explores the classification of radiological imaging techniques, specifically including X-ray imaging, Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and ultrasound imaging. Furthermore, it analyzes the practical application of these key technologies in tumor diagnosis and propose new ideas. In the end, the advantages and characteristics of radiology imaging technology are evaluated, and two limitations are also pointed out, which deserves profound reflection.

The Effect of Venetoclax Combined with Azacitidine on the Clinical Efficacy, Immune Function, and Adverse Reactions in Elderly Patients with Acute Myeloid Leukemia

Zhenfeng Sheng — Wed, 02 Jul 2025 15:46:15 +0800

Objective: To evaluate the immune function and safety of Venetoclax combined with Azacitidine in the treatment of elderly patients with acute myeloid leukemia (AML). Methods: Sixty-eight elderly AML patients who visited the hospital from January 2021 to December 2024 were selected as samples and randomly divided into two groups. Group A was treated with Venetoclax and Azacitidine, while Group B was treated with Azacitidine alone. Immune indicators, inflammatory factors, tumor markers, and adverse reactions were compared between the two groups. Results: The levels of CD3+, CD4+, and CD8+ in Group A were higher than those in Group B (P < 0.05). The tumor necrosis factor-α (TNF-α) level in Group A was lower than that in Group B, while the interferon-γ (IFN-γ) level was higher (P < 0.05). The levels of cyclooxygenase-2 (COX-2), lactate dehydrogenase (LDH), and vascular endothelial growth factor (VEGF) in Group A were lower than those in Group B (P < 0.05). The adverse reaction rate in Group A was lower than that in Group B (P < 0.05). Conclusion: The combination of Venetoclax and Azacitidine in the treatment of elderly AML patients can improve immune function, inhibit inflammation, delay disease progression, and is safe and efficient.

Oversampling Technology and Its Applications in Biomedical Signal Detection

Xinyu Yang — Wed, 02 Jul 2025 16:28:33 +0800

This paper deeply explores oversampling technology and its applications in biomedical signal detection. It first expounds on the significance of oversampling technology in biomedical signal detection, and then analyzes the application strategies of oversampling technology in this field. On this basis, it details the specific applications of oversampling technology in electrophysiological signal detection, biomedical imaging signal processing, and other biomedical signal detections, and verifies its effectiveness through practical case analysis, aiming to provide certain references for relevant researchers.

Effectiveness of Remazolam Combined with Alfentanil for Fiberoptic Bronchoscopy in Elderly Debilitated Patients

Fei Chai, Qiaoying Cai, Rongfang Liu — Wed, 02 Jul 2025 16:33:09 +0800

Objective: To analyze the application value of remazolam compound alfentanil anesthesia regimen in fiberoptic bronchoscopy in elderly debilitated patients. Methods: Seventy-two cases of elderly debilitated patients who underwent fiberoptic bronchoscopy in the Department of Respiratory Medicine of a hospital from August 2023 to July 2024 were selected, and were divided into the control group and the observation group using the mean score method, with 36 cases in each group. In both groups, 7–10 μg/kg alfentanil was injected intravenously after oxygen denitrification, and 1 min later propofol 1.5 mg/kg was given intravenously in the control group and remazolam 0.3 mg/kg was given intravenously in the observation group. Subsequently, mivacurium chloride 0.1mg/kg IV was given to both groups. Propofol 5mg/(kg-h) was given in the control group and remazolam 0.5mg/(kg-h) was given intravenously pumped in the observation group during anesthesia maintenance. Changes in vital signs such as HR, MAP and SpO₂and the occurrence of adverse reactions were recorded in the two groups before anesthesia administration (T₁), at the moment of placing fiberoptic bronchoscope (T₂), at the moment of placing the tracheal tube (T₃), and at 1 min after placing the tracheal tube (T₄). Results: Compared with T₁, patients in the observation group had lower MAP at T₂, T₃, T₄and lower SpO₂at T₃, T₄(P < 0.05); in the control group, HR slowed down at T₂, T₃, T₄and MAP and SpO₂decreased at T₂, T₃, T₄(P < 0.05). SpO₂at T₃ and T₄ was lower in both groups compared with that at T₂(P < 0.05). SpO₂ at T₄was lower in the control group compared with that at T₃(P < 0.05). Compared with the control group, patients in the observation group suffered from increased HR and elevated MAP at T₂, T₃, and T₄, and increased SpO₂at T₃and T₄(P < 0.05). The incidence of intraoperative hypotension and bradycardia in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05). The incidence of intraoperative choking and coughing, postoperative hypoxemia, nausea and vomiting, and dizziness were found in the patients of both groups, drowsiness and other adverse reactions incidence rate comparison, the difference are not statistically significant (P > 0.05). Conclusion: Remazolam and alfentanil are used in fiberoptic bronchoscopy for elderly debilitated patients with remarkable effect, which can effectively improve the vital signs of patients, reduce the risk of intraoperative hypotension, bradycardia, and other adverse reactions, and have high anesthetic effectiveness and safety.

Impact of Spiritual Care Nursing Based on the “Four-full Framework” on Liver Cancer Patients

Lijun Zhu, Huajun Lin — Wed, 02 Jul 2025 16:38:04 +0800

Objective: To explore the impact of spiritual care nursing based on the “Four-full Framework” (whole-person, whole-process, whole-department, whole-society) on the spiritual status, psychological distress, and quality of life of liver cancer patients. Methods: A total of 120 terminally ill liver cancer patients admitted to the hospital from January 2022 to December 2023 were divided into a control group (60 cases, receiving routine nursing) and an observation group (60 cases, receiving routine nursing plus spiritual care nursing based on the four-full framework) according to their admission order. Both groups were intervened for 4 consecutive weeks. The two groups were compared in terms of death attitude, spiritual status, psychological distress, and quality of life. Results: After intervention, the observation group had lower scores in death avoidance, death fear, escape acceptance, and psychological distress, while higher scores in natural acceptance, approach acceptance, all dimensions of spiritual status, psychological resilience, and all aspects of quality of life compared with the control group, with statistically significant differences (P ＜ 0.05). Conclusion: Spiritual care nursing based on the four-full framework can effectively help terminally ill liver cancer patients face death positively, improve their spiritual status, reduce psychological distress, and enhance their quality of life.