https://ojs.bbwpublisher.com/index.php/JCNR <p align="justify"><em>Journal of Clinical and Nursing Research (JCNR) </em>is an international, peer reviewed and open access journal that seeks to promote the development and exchange of knowledge which is directly relevant to all clinical and nursing research and practice. Articles which explore the meaning, prevention, treatment, outcome and impact of a high standard clinical and nursing practice and discipline are encouraged to be submitted as original article, review, case report, short communication and letters. The covered topics include, but are not limited to: development of clinical and nursing research, evaluation, evidence-based practice and scientific enquiry; patients and family experiences of health care; clinical and nursing research to enhance patient safety and reduce harm to patients; ethics; clinical and nursing history; medicine.</p> <p align="justify">&nbsp;</p> Bio-Byword Scientific Publishing PTY LTD en-US Journal of Clinical and Nursing Research 2208-3685 https://ojs.bbwpublisher.com/index.php/JCNR/article/view/15346 <p><em>Objective</em>: To investigate the clinical efficacy of a novel elastic compression palatal splint, independently developed by our team, following the surgical resection of palatal cysts and benign tumors. <em>Methods</em>: A total of 90 patients who underwent surgery for benign palatal lesions at the Department of Oral and Maxillofacial Surgery of our hospital between January 2023 and December 2025 were selected as study subjects. Using a random number table, they were divided into three groups, A, B, and C, with 30 patients in each group. Group A underwent postoperative compression fixation using a purse-string suture with iodoform gauze; Group B used a conventional rigid palatal splint for compression fixation; and Group C received postoperative intervention with the newly developed elastic compression palatal splint. Patients were followed up to observe their postoperative recovery, and comparisons were made across the three groups regarding the incidence of dental damage, wound infection rates, wound healing times, and postoperative comfort scores.<em> Results</em>: The incidence of dental trauma and wound infection in Group C was significantly lower than in Groups A and B; wound healing time in Group C was markedly shorter than in Groups A and B; and the visual analog scale (VAS) comfort scores for postoperative wear in Group C were significantly better than in the other two groups. The differences in data comparisons between the groups were all statistically significant (<em>p</em> &lt; 0.05). <em>Conclusion</em>: The novel elastic compression palatal splint enables uniform elastic compression of the postoperative palatal wound, provides visual and adjustable pressure, and facilitates unobstructed drainage of wound exudate. It effectively mitigates the drawbacks of traditional surgical procedures, significantly reduces the incidence of postoperative complications, shortens the wound healing period, and improves the patient’s postoperative wearing experience. The structural design of this splint meets the clinical requirements for precision treatment; it is simple to use, highly safe, and widely applicable. It aligns with the trend towards precision medicine in dentistry and possesses significant value for clinical promotion and application.</p> Junli Zhu Shuo Zhang Jing Wang Copyright (c) 2026 Author(s) 2026-06-30 2026-06-30 10 6 1 9 10.26689/jcnr.v10i6.15346 https://ojs.bbwpublisher.com/index.php/JCNR/article/view/15347 <p><em>Objective:</em> To investigate the effects of Longzuan Tongbi Decoction on ischemic myocardial angiogenesis in rats with myocardial infarction (MI), and to analyze its regulatory effect on the expression of angiogenesis-related factors. <em>Methods:</em> A total of 120 healthy, clean-grade female Sprague-Dawley (SD) rats were randomly divided into six groups (20 rats per group): sham surgery (normal control) group, model group, Shexiang Baoxin Pill (positive control) group, as well as low-, medium-, and high-dose groups of Longzuan Tongbi Decoction. The MI model was established by left coronary artery ligation; the sham surgery group underwent threading without ligation. Postoperatively, each treatment group received daily oral administration of the corresponding medicine (the low-, medium-, and high-dose groups of Longzuan Tongbi Decoction received 1 mL, 2 mL, and 4 mL of the extract, respectively; the positive control group received Shexiang Baoxin Pill), while the sham surgery and model groups received an equal volume of saline. Treatment continued for 6 weeks. At the end of the experiment, the ratio of myocardial infarct size to left ventricular area was measured, and the number and density of microvessels in the MI border zone were assessed. <em>Results:</em> Compared with the model group, the ratio of myocardial infarct size to left ventricular area was significantly reduced in each dose group of Longzuan Tongbi Decoction (<em>p</em> &lt; 0.05), and the efficacy was comparable to that of the Shexiang Baoxin Pill group. Regarding angiogenesis promotion, the number and density of microvessels in the infarct border zone were significantly higher in each dose group of Longzuan Tongbi Decoction than in the model group (<em>p</em> &lt; 0.05); among these, the pro-angiogenic effect of the medium- and high-dose groups was significantly superior to that of the Shexiang Baoxin Pill group (<em>p</em> &lt; 0.05), while no significant difference was observed between the low-dose group and the positive control group (<em>p</em> &gt; 0.05). <em>Conclusion:</em> Longzuan Tongbi Decoction can effectively reduce the extent of myocardial infarction and exert a cardioprotective effect by promoting local angiogenesis in ischemic myocardium, and this effect exhibits a dose-dependent relationship within a certain range.</p> Zheng Huang Qiao Zeng Jianhui Gu Liping Lu Dafen Li Yongxi Zhou Copyright (c) 2026 Author(s) 2026-06-30 2026-06-30 10 6 19 26 10.26689/jcnr.v10i6.15347