Journal of Clinical and Nursing Research

Application Effect of Refined Management Mode in Orthopedic Nursing Management

Xiaoyan He — 2025-04-03

This study aimed to explore the application method and effect of a refined management model in orthopedic nursing management. A total of 190 patients treated at our hospital were enrolled and divided into two groups. Ninety-five patients treated from January to May 2023 served as the control group, receiving conventional orthopedic nursing management, while another 95 patients treated from June to December 2023 formed the observation group, in which a refined management model was implemented. The nursing management outcomes of the two groups were compared. The results showed that patients in the observation group had a shorter hospital stay, a lower incidence of postoperative complications and nursing risk events, and higher nursing satisfaction compared to the control group (P < 0.05). These findings indicate that the refined management model can effectively improve nursing quality, reduce orthopedic nursing risk events, and enhance patient satisfaction, demonstrating significant clinical value.

Application Research of Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Machine in Patients with End-Stage Renal Disease Undergoing Peritoneal Dialysis

Huihui Mu — 2025-04-03

This study analyzed the therapeutic effects of continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) on patients with end-stage renal disease. Fifty patients admitted between January 2024 and December 2024 were randomly assigned to two groups, with the observation group receiving APD and the reference group receiving CAPD. Renal function indicators, nutritional indicators, mineral metabolism, urine volume, and ultrafiltration volume changes were compared between the two groups. After treatment, the observation group showed lower renal function indicators, higher nutritional indicators, and better mineral metabolism levels compared to the reference group (P < 0.05). While there was no significant difference in urine volume between the two groups (P > 0.05), the observation group demonstrated superior ultrafiltration volume (P < 0.05). These findings suggest that APD offers better clinical outcomes than CAPD by improving renal function, nutritional status, mineral metabolism regulation, and ultrafiltration efficiency in patients with end-stage renal disease.

Research Progress of Intelligent Auscultation Technology Based on Deep Learning in Congenital Heart Disease

Wenlong Wang — 2025-04-03

Congenital heart disease (CHD) is one of the most common congenital birth defects. With the deepening of people’s understanding of CHD disease and the continuous improvement of screening methods, children with CHD have been able to receive diagnosis and treatment at an early stage, thus improving the survival rate and quality of life. The main means of early screening of CHD are heart sound auscultation and percutaneous oxygen saturation detection. At present, there are relatively mature commercial equipment for transcutaneous oximetry, but the heart sound assessment is greatly affected by personal experience and external factors, which is prone to misdiagnosis and missed diagnosis. In recent years, the continuous development of artificial intelligence (AI) makes the digital collection, storage, and analysis of heart sound signals, and then makes the intelligent auscultation-assisted diagnosis technology of cardiovascular diseases possible. At present, it is based on deep learning. DL’s AI algorithm has been extensively studied in CHD cardiac sound auscultation assisted diagnosis, but most of them are still in the algorithm research stage and are implemented based on specific data sets, and have not been verified in clinical Settings. In this paper, the development and research status of AI auscultation technology at the current stage are reviewed, the development of DL based intelligent auscultation technology in the field of CHD in recent years is summarized and the problems to be solved in the clinical application of heart sound auscultation are proposed.

The Application Effect of “Expiration Manager” Mini Program in the Validity Management of Articles in Ward

Xiaofei Mi — 2025-04-02

The purpose of this study is to investigate the effectiveness of the “expiration manager” mini program in managing the validity of ward items. The program was used to manage frequently and infrequently used consumables by setting up an automatic reminder function. The item failure rate and the time required for nurses to conduct counts over 6 months before and after implementation were compared, as well as evaluated system availability using the System Usability scale (SUS). Results showed that after implementing the mini program, both the item failure rate and non-recognition rate significantly decreased (P < 0.05), while the inspection pass rate significantly increased (P < 0.05), and the monthly inventory time was reduced (P < 0.05). The SUS evaluation yielded a total score of 74.38 ± 11.73, with learnability at 80.21 ± 20.27 and availability at 72.92 ± 11.18, all indicating good user acceptance. In conclusion, the “expiration manager” mini program can effectively improve the efficiency of item expiration management, reduce the risk of expiration, and save inspection time, thereby demonstrating high user acceptance and promising potential for wider adoption.

Application and Research Progress of Moxibustion Therapy in the Care of Patients with Alzheimer’s Disease

Xuyifan Bao — 2025-04-02

With the intensification of aging, the number of patients with Alzheimer’s disease (AD) in China has increased, which has brought a heavy burden to families and society. However, there is currently a lack of specific curative drugs for AD and commonly used clinical drugs can only relieve symptoms while accompanied by adverse reactions. Traditional Chinese medicine nursing techniques have unique advantages in the treatment of AD. Moxibustion therapy can improve cognitive function and improve living ability by stimulating acupoints with warmth. Therefore, this article summarizes the research progress of moxibustion therapy in the treatment of AD from the understanding of AD in traditional Chinese and Western medicine, an overview of moxibustion therapy, the mechanism of moxibustion therapy in the treatment of AD, and the clinical application of moxibustion therapy in the treatment of AD. It is hoped to provide a reference for the application of moxibustion therapy in AD patients.

Analysis and Countermeasures of Nursing Problems in the Placement of PICC Guided by Endocardial Electrocardiogram Positioning Technology

Hui Chi — 2025-04-03

This study aimed to explore an effective nursing plan for peripherally inserted central catheter (PICC) placement guided by endocardial electrocardiogram (ECG) positioning technology and to analyze related nursing problems and countermeasures. A total of 96 patients who underwent PICC placement using ECG-guided positioning technology in our hospital from January 2024 to December 2024 were selected and randomly divided into an experimental group (n = 48) and a control group (n = 48) using a random number table. The control group received routine basic nursing care, while the experimental group was provided with comprehensive high-quality nursing care. The results showed that the success rate of one-time catheter placement was significantly higher in the experimental group than in the control group (P < 0.05), while the incidence of complications was notably lower in the experimental group (P < 0.05). These findings suggest that comprehensive high-quality nursing care during PICC placement guided by ECG positioning technology can effectively enhance the success rate of catheter placement and reduce complications, indicating that this nursing approach is valuable for clinical promotion and application.

Application of Specialist Nursing Intervention of Intravenous Therapy to Elderly Patients with PICC

Yongtao Shang — 2025-04-03

This study aimed to explore the specific application effect of specialist nursing intervention in intravenous therapy on elderly patients with peripherally inserted central catheters (PICC). From November 2023 to November 2024, a total of 60 elderly patients with PICC admitted to Guiqian International General Hospital were selected as research subjects. Using a digital random table method, these patients were randomly divided into a control group and an experimental group, with 30 patients in each. The control group received routine nursing care, while the experimental group received specialized intravenous therapy nursing intervention in addition to routine care. The nursing effects of both groups were comprehensively evaluated, including treatment compliance, psychological state, quality of life, incidence of complications, and satisfaction with nursing care. The results showed that after the intervention, the treatment compliance in the experimental group was significantly higher than that of the control group (P < 0.05). Additionally, scores on the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were markedly lower in the experimental group compared to the control group (P < 0.05), indicating improved psychological well-being. The experimental group also scored higher in all dimensions of quality of life (P < 0.05), and had a lower complication rate and higher satisfaction with nursing care (P < 0.05). In conclusion, the application of specialized intravenous therapy nursing intervention in the care of elderly patients with PICC can significantly enhance treatment compliance, improve psychological status, elevate quality of life, and reduce complications, demonstrating strong clinical value and providing important guidance for future treatment and nursing of such patients.

The Effect of the Integrated Healthcare Working Model on Compliance Behaviour and Complications in Children with Inguinal Hernia in the Perioperative Laparoscopic Period

Qian Sun — 2025-04-03

This study aimed to explore the application effect of the medical and nursing integration working mode in children with inguinal hernia undergoing laparoscopic surgery and to provide a basis for its clinical promotion. A total of 70 children with inguinal hernia admitted to our hospital from July 2023 to June 2024 and treated with laparoscopic surgery were selected as study subjects and randomly divided into an observation group and a control group, with 35 cases in each. Both groups received routine nursing care, while the observation group additionally adopted the integrated medical and nursing working mode, including systematic health education, psychological interventions, and postoperative follow-up from admission to discharge. The anxiety and depression scores of the two groups before and after surgery, medical compliance index, and incidence of complications during hospitalization were compared. Results showed that the preoperative anxiety scores of the observation and control groups were (14.01 ± 1.07) and (14.62 ± 2.31), respectively, with no statistically significant difference (P > 0.05); however, postoperative anxiety scores were significantly lower in the observation group (4.01 ± 0.77) compared to the control group (6.62 ± 0.31) (P < 0.05). Similarly, preoperative depression scores were (15.11 ± 1.22) in the observation group and (15.41 ± 2.01) in the control group (P > 0.05), but postoperative depression scores were significantly reduced in the observation group (4.24 ± 0.61) compared to the control group (7.12 ± 0.54) (P < 0.05). After intervention, the medical compliance behavior index in the observation group was (83.31 ± 5.92), significantly higher than (75.34 ± 6.73) in the control group (P < 0.05). Regarding postoperative complications, only 1 case (2.86%) occurred in the observation group, while 8 cases (22.86%) were reported in the control group, showing a statistically significant difference (P < 0.05). In conclusion, the medical and nursing integration working mode effectively improves the perioperative psychological state of children, enhances medical compliance, reduces postoperative complications, and is worthy of widespread clinical application.

Effects of Rehabilitation Nursing Combined with Psychological Intervention Based on Mind Mapping Model on Emotional State and Treatment Compliance of Patients with Nephrotic Syndrome

Xiuju Huang — 2025-04-04

Objective: To evaluate the value of rehabilitation nursing based on mind mapping model combined with psychological intervention for patients with nephrotic syndrome (NS). Methods: A total of 60 patients with NS who visited our hospital from January 2024 to December 2024 were selected as samples and randomly divided into groups. The observation group received rehabilitation nursing based on the mind mapping model combined with psychological intervention, while the control group received routine intervention. The differences in emotional scores, self-care ability scores, compliance, and complications were compared between the two groups. Results: The anxiety (SAS) and depression (SDS) scores of the observation group were lower than those of the control group, while the self-care ability scale (ESCA) score was higher than that of the control group (P < 0.05). The compliance rate of the observation group was higher than that of the control group (P < 0.05). The complication rate of NS in the observation group was lower than that in the control group (P < 0.05). Conclusion: Rehabilitation nursing based on the mind mapping model combined with psychological intervention can enhance self-care ability, reduce negative emotions, and reduce complications in NS nursing, which is efficient and feasible.

Analysis of Complications in Preterm Infants with Twin and Singleton of Different Gestational Ages

Fang Wang — 2025-04-03

This study aimed to compare the complications of preterm twins versus singletons and analyze differences across gestational ages. Preterm twins delivered between 2 March 2022 and 6 November 2022 were compared to an age-matched control group of singletons, involving 65 twins and 103 singletons. The most common complication in premature infants was neonatal jaundice (87.72%), followed by patent foramen ovale (79.76%) and neonatal respiratory distress syndrome (NRDS) (57.14%). Twins had significantly higher Apgar scores at 1, 5, and 10 minutes compared to singletons. However, twins showed a higher incidence of ventricular septal defect (VSD) (7.69%) than singletons, with a statistically significant difference. In contrast, twins exhibited significantly lower rates of neonatal jaundice (78.46%), electrolyte imbalance (18.4%), and acid-base imbalance (9.23%) compared to singletons. Furthermore, as gestational age increased, the incidence of intrauterine infection, electrolyte and acid-base imbalances, neonatal coagulation disorders, patent ductus arteriosus (PDA), anemia, and NRDS in preterm infants gradually decreased, with all differences reaching statistical significance (P < 0.05). These findings highlight the importance of close monitoring and timely management of complications in premature infants to prevent severe outcomes.

Analysis of the Clinical Efficacy of Budesonide Combined With Ambroxol Inhalation Therapy for Neonatal Pneumonia

Yanyan Han — 2025-04-03

This study explores the clinical efficacy of budesonide combined with ambroxol inhalation therapy for neonatal pneumonia. A total of 68 neonatal pneumonia patients treated at Li County Hospital from January 2023 to December 2024 were randomly divided into a monotherapy group and a combination group, with 34 patients in each. The monotherapy group received ambroxol inhalation therapy, while the combination group received budesonide inhalation therapy in addition to ambroxol. The recovery progress, blood gas analysis indicators, inflammatory response improvement, and overall clinical efficacy were compared between the two groups. Results showed that the combination group experienced a significantly shorter time for body temperature normalization (3.36 ± 0.58 days vs. 4.59 ± 0.45 days), oxygen inhalation duration (4.89 ± 0.57min vs. 6.96 ± 0.79min), disappearance of shortness of breath and cough (4.56 ± 0.29 days vs. 6.63 ± 0.75 days), and resolution of lung wet rales (5.62 ± 1.46 days vs. 7.92 ± 1.28 days) compared to the monotherapy group (P < 0.05). Additionally, the total effective rate was significantly higher in the combination group (97.06%) than in the monotherapy group (73.52%) (P<0.05). Post-treatment, the combination group exhibited significantly better blood gas analysis and inflammatory response indicators (P<0.05). These findings suggest that budesonide combined with ambroxol inhalation therapy can effectively improve blood oxygen saturation, reduce inflammation, promote faster recovery, and enhance overall clinical efficacy, making it a reliable treatment option for neonatal pneumonia.

Research Progress of Kinesiophobia in Patients with Rheumatoid Arthritis

Na Gao — 2025-04-03

Kinesiophobia is recognized as one of the primary barriers for patients participating in physical rehabilitation. This fear can create psychological obstacles to engaging in rehabilitation exercises or daily activities, leading to a significant decline in health-related quality of life. Currently, kinesiophobia has primarily been studied in the context of chronic pain and cardiovascular diseases, while its awareness and intervention in the field of Rheumatoid Arthritis have not received sufficient attention. Assisting patients in overcoming kinesiophobia is particularly crucial for initiating physical activity in Rheumatoid Arthritis. This article aims to review the assessment tools, influencing factors, and intervention strategies for kinesiophobia in patients with Rheumatoid Arthritis, with the goal of providing clinical healthcare professionals with references and insights for developing and implementing interventions, thereby promoting active rehabilitation among patients.

Analysis of the Effect of Safety Culture Construction in Nursing Management of Infectious Disease Area

Xing Wang — 2025-04-04

Objective: To explore the effect of applying safety culture construction in nursing management of infectious disease areas. Methods: During the one-year period from January 2024 to December 2024, patients admitted to the infectious disease area of our hospital were randomly selected for the study. 92 patients were divided into two groups using a computerized double-blind method for intervention. The control group received routine nursing management, while the observation group applied safety culture construction management. The effects of nursing management in the two groups were studied and compared. Results: Before management, the nursing management quality scores of the two groups were evaluated, showing little difference in various scores, and the difference was not statistically significant (P > 0.05). Through the implementation of nursing management, the scores of the two groups were significantly improved, and the observation group had significantly higher scores compared to the control group (P < 0.05). Compared to the incidence of nursing risk events, the observation group (6.52%) was significantly lower than the control group (30.43%), and there was a significant difference between the two groups (P < 0.05). The observation group had significantly higher satisfaction scores for nursing skills, health education, service attitude, and professionalism compared to the control group, indicating patient satisfaction with safety culture construction (P < 0.05). Conclusion: Applying safety culture construction in nursing management of infectious disease areas has a preventive effect on nursing risk events and is beneficial for improving patients’ risk cognition level.

The Impact of Psychological Resilience Support Combined with Midwife Integrated Full-course Care on Breastfeeding of Primiparous Women

Lu Xu — 2025-04-04

Objective: To analyze the nursing effect of psychological resilience support combined with midwife-integrated full-course care on primiparous women. Methods: A total of 66 primiparous women who were admitted to the hospital for delivery from April 2022 to April 2024 were selected, all of whom underwent vaginal delivery. They were randomly divided into two groups using a random number table. The combined group received integrated full-course care from midwives under the premise of psychological resilience support, while the conventional group only received routine care. The nursing effects were compared between the two groups. Results: The breastfeeding rate of the combined group was higher than that of the conventional group at different time points after delivery, the postpartum complication rate was lower than that of the conventional group, the psychological resilience scores were higher than those of the conventional group at different stages of labor, and the nursing satisfaction was higher than that of the conventional group (P < 0.05). Conclusion: Under the premise of psychological resilience support, integrated full-course care implemented by midwives can improve the breastfeeding rate, actively prevent postpartum complications, significantly improve psychological resilience, and achieve better nursing satisfaction.

The Impact of Continuous Nursing Combined with KAP Intervention Guided by the Interactive Achievement Theory on Blood Glucose Control and Healthy Behaviors of Patients with Gestational Diabetes Mellitus

Yuan Yuan — 2025-04-04

Objective: To analyze the nursing effect of implementing continuous nursing combined with knowledge, attitude, and practice (KAP) intervention under the guidance of interactive goal-setting theory for patients with gestational diabetes mellitus (GDM). Methods: A total of 68 patients with GDM who were admitted to the hospital between December 2021 and December 2023 were selected and randomly divided into two groups using a random number table. The combined group (34 cases) received continuous nursing combined with KAP intervention under the premise of interactive goal-setting theory, while the conventional group (34 cases) received routine nursing care. Blood glucose control, health behavior scores, and other indicators were compared between the two groups. Results: After nursing, the blood glucose level in the combined group was lower than that in the conventional group, and the scores for health behavior and self-management ability were higher than those in the conventional group (P < 0.05). Conclusion: Combined nursing can improve blood glucose control in patients with GDM, standardize their health behaviors, and cultivate their self-management skills.

Molecular Mechanism Study on the Expression of TF-MPs in Cervical Cancer Patients and Deep Venous Thrombosis

Qingrong Hu — 2025-04-04

Objective: To explore the molecular mechanism of tissue factor-positive microparticles (TF-MPs) expression and deep venous thrombosis (DVT) in patients with cervical cancer. Methods: A total of 200 patients with cervical cancer and benign cervical diseases who were hospitalized in the First Department of Gynecologic Oncology of Gansu Provincial Cancer Hospital from January 2024 to December 2025 were selected, including 100 patients with benign cervical diseases as the control group and 100 patients with cervical cancer as the experimental group. Enzyme-linked immunosorbent assay (ELISA) was used to detect the expression level of TF-MPs in peripheral blood samples from patients with cervical cancer and healthy controls. At the same time, real-time quantitative PCR was used to explore the molecular mechanism of TF-MPs promoting DVT formation. Finally, the formation of DVT in the two groups was observed and recorded, and the incidence of DVT was counted. Results: Experimental measurements showed that the expression levels of TF-MPs, coagulation factors FVII, FX, PT, and inflammatory factors IL-6 and TNF-a in the experimental group were significantly higher than those in the control group (P < 0.01); the incidence of DVT in the experimental group was up to 38%, far exceeding the 6% in the control group (P < 0.001). Conclusion: Abnormal expression of TF-MPs in patients with cervical cancer is an important risk factor for DVT. Through in-depth analysis of the molecular mechanism of TF-MPs promoting DVT formation, it provides a new perspective and theoretical basis for the prevention and treatment of DVT in patients with cervical cancer. In the future, intervention strategies targeting TF-MPs and their related molecular pathways are expected to become effective ways to reduce the incidence of DVT in patients with cervical cancer.

Effects of Duhuo Jisheng Decoction Combined with Warm Acupuncture and Moxibustion on ODI Index and Lumbar Activity of Patients with Lumbar Disc Herniation

Shugang Peng — 2025-04-04

Objective: To explore the effect of combining Duhuo Jisheng decoction with warm acupuncture and moxibustion in the treatment of patients with lumbar disc herniation. Methods: Using a random number table method, a total of 100 patients with lumbar disc herniation treated at Xianning Matang Hospital of Traditional Chinese Medicine from January 2021 to December 2023 were divided into a control group of 50 patients treated with Duhuo Jisheng decoction and a study group of 50 patients treated with Duhuo Jisheng decoction combined with warm acupuncture and moxibustion. The TCM syndrome scores, lumbar function, lumbar pain, and lumbar activity were compared between the two groups. Results: After intervention, the TCM syndrome scores, ODI, and VAS scores of both groups showed a decreasing trend compared to before intervention, and the decreasing trend was more significant in the study group (P < 0.05). After intervention, the JOA and lumbar activity indicators of both groups showed an increasing trend compared to before intervention, and the increasing trend was more significant in the study group (P < 0.05). Conclusion: Duhuo Jisheng decoction combined with warm acupuncture and moxibustion is an effective and safe treatment method for lumbar disc herniation, which can improve lumbar function and activity.

Clinical Study on Risk Factor Prediction of Pulmonary Embolism in Northern Shaanxi

Ying Liu — 2025-04-02

The aim of this study is to analyze the risk factors and clinical characteristics of pulmonary embolism in northern Shaanxi. In this study, 162 patients with venous thrombosis admitted between June 2023 and June 2024 underwent CT pulmonary angiography to investigate the risk factors and clinical characteristics of pulmonary embolism (PE) in northern Shaanxi. The patients were divided into a control group (no PE, n = 98) and a study group (PE, n = 64) based on the presence or absence of PE. Data were collected using a Case Report Form, and statistical analyses were conducted to summarize clinical features and risk factors, followed by three months of targeted therapy. Significant differences were observed between the two groups in clinical manifestations such as pleural pain, dyspnea, and hemoptysis, as well as in past medical histories (including malignant tumor history and right ventricular dysfunction), physical signs like lung rales, and laboratory parameters such as hemoglobin, albumin, white blood cell count, D-dimer, blood oxygen saturation, total cholesterol, triglycerides, and high-density lipoprotein cholesterol (all P < 0.05). Multivariate logistic regression analysis identified pleural pain, dyspnea, malignancy, right ventricular dysfunction, lung rales, D-dimer, white blood cell levels, and blood oxygen saturation as risk factors for PE in patients with venous thrombosis. Following targeted therapy, the proportions of patients with pleural pain, dyspnea, and lung rales decreased significantly, with concurrent reductions in right ventricular end-diastolic inner diameter (RVD), D-dimer, and white blood cell levels, and a significant increase in blood oxygen saturation. These findings suggest that early prevention and intervention based on these risk factors can effectively reduce the incidence of PE in northern Shaanxi.

Clinical Evaluation of External Application of Granulation-Promoting Jade and Red Paste in the Treatment of Diabetic Foot

Liren Ma — 2025-04-02

The purpose of this study is to analyze the clinical effect of external application of Granulation-Promoting Jade and Red paste in the treatment of diabetic foot. This study was carried out in Pingdingshan Traditional Chinese Medicine Hospital from December 2023 to December 2024. A total of 80 patients were selected as research objects, all of whom were diagnosed diabetic foot patients. They were treated and divided into two groups based on different methods, the group names were “experimental group” and “control group”. Patients in the control group were treated with Vaseline on the basis of external treatment, and patients in the experimental group were treated with Granulation-Promoting Jade and Red paste on the basis of external treatment, and the clinical effects of different treatment methods were compared and analyzed. The results showed that the effective rate in the experimental group was significantly higher (95.00%) compared to the control group (75.00%) (P < 0.05). Furthermore, the experimental group exhibited notably shorter wound healing time and granulation tissue growth time, indicating faster and better recovery (P < 0.05). Additionally, post-treatment Wagner grading revealed that the proportion of patients in advanced grades (4, 5, and 6) was significantly lower in the experimental group, whereas a higher proportion of patients achieved lower grades (0, 1, and 2), demonstrating improved clinical outcomes (P < 0.05). In conclusion, Granulation-Promoting Jade and Red Paste shows a significant therapeutic effect in treating diabetic foot, effectively promoting wound healing, improving clinical symptoms, and enhancing overall recovery.

Effect of Evidence-Based Nursing Intervention on MIGILL Score of Patients after Endoscopic Resection of Nasal Polyps

Yang Li — 2025-04-03

This study aimed to investigate the effect of evidence-based nursing intervention on patients undergoing nasal endoscopic resection of nasal polyps, particularly focusing on its impact on MIGILL’s pain scores. A total of 74 patients who underwent endoscopic nasal polyp resection were randomly divided into two groups using a random number table method. The outcomes of evidence-based nursing intervention in the observation group were compared with those of the control group. The results showed that the MIGILL pain scores in the observation group were significantly lower than those in the control group, and both hospitalization time and cost were notably reduced (P < 0.05). Additionally, patients in the observation group demonstrated better psychological states and experienced fewer postoperative complications compared to the control group (P < 0.05). Furthermore, the quality of life scores were significantly higher in the observation group (P < 0.05). These findings suggest that evidence-based nursing intervention after endoscopic resection of nasal polyps is highly effective in alleviating postoperative pain, improving emotional well-being, minimizing complications, reducing hospital stay and expenses, and enhancing overall quality of life, indicating its potential value for broader clinical application.

Ambulatory Blood Pressure Characteristics and Risk Factors for Circadian Rhythm Abnormalities in Elderly Patients with Hypertension

Yaqian Huang — 2025-04-04

Objective: To analyze the characteristics of ambulatory blood pressure in elderly patients with hypertension and find out the risk factors of abnormal circadian rhythm. Methods: According to the circadian rhythm of patients’ blood pressure, they were divided into group A, group B, and group C, and all the data of hypertension patients in this study were collected, including age, gender, BMI, smoking, drinking, basic diseases (diabetes, cerebrovascular disease, hyperlipidemia, etc.), fasting blood glucose, ambulatory blood pressure (24-hour mean systolic pressure, 24-hour mean diastolic pressure, daytime mean systolic pressure and daytime mean diastolic pressure). Results: There were significant differences in mean systolic blood pressure and mean diastolic blood pressure at night among group A, group B and group C (P < 0.05). Age, hyperlipidemia and fasting blood glucose were risk factors for circadian rhythm abnormality (P < 0.05), and 24-hour urinary sodium was a protective factor for circadian rhythm abnormality (P < 0.05). Conclusion: Age, hyperlipidemia and fasting blood glucose are risk factors for circadian rhythm abnormality (P < 0.05), and 24-hour urinary sodium is a protective factor for circadian rhythm abnormality (P < 0.05).

Visualization Analysis of Research Hotspots on Timing in Right Theory in the Field of Nursing

Bo Fang — 2025-04-03

Objective: Based on the CNKI database, this study analyzes the current research status and hotspots of the Timing it Right (TIR) Theory in China, providing insights and references for its further development in the field of nursing. Methods: Using bibliometric methods and Citespace software, this study conducts a statistical and visual analysis of publications on TIR Theory from CNKI, focusing on annual publication volumes, author collaboration networks, high-frequency keywords, and emergent terms. Results: The study statistically analyzed the time distribution and research hotspots of 117 relevant papers. The annual publication volume shows a gradual upward trend, though the overall volume remains low. High-frequency keywords such as “family nursing,” “quality of life,” “acute myocardial infarction,” and “stroke” form the core research themes. Conclusion: Research on TIR Theory in China’s nursing field is still in the exploratory stage, and its attention and emphasis need to be enhanced. As it aligns with modern medical models, its application scope in nursing is expanding, promoting the high-quality, scientific, and diversified development of nursing services in China.

Clinical and CT Imaging Features of Brucellar Spondylitis and Differential Diagnosis

Yan Guo — 2025-04-02

This study aims to explore the clinical and CT imaging features of brucellosis spondylitis (BS) and to strengthen the clinical cognition to reduce misdiagnosis and mistreatment. In this study, clinical and CT imaging data of 106 patients with BS diagnosed in the Second Hospital of Hohhot and the Third Hospital of Baotou were collected from March 2023 to September 2024 and retrospectively analyzed by clinical manifestations, CT imaging, and disease regression. In 106 patients, 58.5% had fever, 98.1% had malaise, 96.2% had excessive sweating, 81.1% had lumbosacral pain, 79.3% had limitation of limb movement, 76.4% had constipation, and 6.6% had urinary retention. For imaging manifestations, the involvement of lumbar, thoracic and cervical vertebrae were 80.2%, 16.9% and 1.9%, respectively. Lesions < 1.0 cm, 1.0–2.0 cm, 2.0–3.0 cm, and > 3.0 cm were found in 49.4%, 29.6%, 19.4%, and 1.6%, respectively. In 106 patients, CT showed round, irregular or worm-like areas of bone destruction, with coexisting osteophytes in 61.5% and no signs of dead bone or pedicle destruction. Interdiscal destruction, spinal canal abscess, ligament injury, and signs of lumbar major muscle compression were rare, accounting for 11.7%, 6.6%, 4.7%, and 3.8%, respectively. Regarding regression, 106 patients with BS treated with antimicrobial therapy or antimicrobial + surgery had a good prognosis. In conclusion, BS has its own characteristics in clinical and imaging aspects and it is easy to distinguish from other common causes of spondylitis bone damage.

Research on the Treatment of Dysphagia Caused by True Bulbar Paralysis after Stroke with Electroacupuncture at Swallowing Points

Shiting Zhu — 2025-04-04

Dysphagia caused by true bulbar paralysis after stroke is a common and serious complication that severely affects patients’ eating ability and quality of life, and significantly increases the risk of complications such as pneumonia and malnutrition. Electroacupuncture at swallowing points stimulates Swallowing 1 and Swallowing 2 acupoints, acting on key areas such as the glossopharyngeal nerve and vagus nerve, stimulating the reconstruction of nerve reflex arcs and the recovery of swallowing function. Therefore, this article analyzes the mechanism and clinical efficacy of electroacupuncture at swallowing points for the treatment of dysphagia caused by true bulbar paralysis after stroke, aiming to provide theoretical support and practical basis for clinical application.

Analysis of the Effect of Care of Patients with Healthcare Integration Model on the Inguinal Hernia Treated with Tension-Free Repair

Qian Sun — 2025-04-04

Objective: To explore the effect of medical and nursing integration mode on the nursing care of patients with inguinal hernia treated by tension-free repair. Methods: A total of 76 cases of inguinal hernia patients admitted to the hospital from September 2023 to August 2024 were selected as study subjects. They were divided into 38 cases each in the control group and the observation group by using the random number table method. The patients in the control group were cared for by the traditional postoperative care mode and the patients in the observation group were given additional medical and nursing care based on the control group, and were observed and analyzed for pain relief, infection, hospital stay, and hospital costs. Results: The VAS score of patients in the observation group was (7.91 ± 2.21) at 1d postoperation and (11.04 ± 3.24) at 1d postoperation in the control group, which was significantly lower than that of the control group, with a statistically significant difference (P < 0.05), and the VAS score of the patients at 6 months postoperation was (4.82 ± 1.81), which was not statistically significant when compared with that of the control patients (4.79 ± 1.45), which was not statistically different from those of the control group (P > 0.05); 3 cases of infection occurred in the at 3d, accounting for the total number of observation group postoperative patients (7.89%), and compared with control group with postoperative 5 cases of infection occurred in the 3 days, accounting for of the total number of patients (13.16%), the postoperative infection rate of the patients in the observation group was significantly reduced, and the difference was statistically significant (P < 0.05). The number of hospitalization days as well as the hospitalization costs of the observation group were significantly lower than those of the control group, and the difference was statistically significant (P < 0.05). Conclusion: The integrated model of medical care has significant advantages in the care of patients with inguinal hernia treated with tension-free repair, which can effectively alleviate early postoperative pain, reduce the rate of infection, shorten the length of hospital stay, and reduce the cost of hospitalization.

The Scope Review of Kinesiophobia in Patients with Chronic Obstructive Pulmonary Disease

Na Gao — 2025-04-04

Objective: To review the current status of research on kinesiophobia, assessment tools, influencing factors, and intervention strategies in patients with chronic obstructive pulmonary disease, aiming to provide a reference for promoting pulmonary rehabilitation in these patients. Methods: A scoping review framework was employed to search databases including CNKI, Wanfang, VIP, China Biology Medicine (CBM), PubMed, Web of Science, and Wiley Online Library. The search time frame spanned from the database inception to May 20, 2024. Two researchers independently screened the literature, summarized, and analyzed the data. Results: A total of 18 articles were included. Commonly used assessment tools included the Tampa Scale for kinesiophobia and the dyspnea beliefs questionnaire. Influencing factors encompassed demographic, disease-related, psychosocial, and BMI-related factors. Intervention methods included inspiratory muscle training, narrative nursing, and cognitive interventions combined with active cycle of breathing techniques. Conclusion: The incidence of kinesiophobia in COPD patients is relatively high and varies among individuals, influenced by multiple factors. There is a need to develop localized assessment tools to identify kinesiophobia in a timely and accurate manner and to further refine intervention strategies.

The Impact of Narrative Nursing Combined with Exercise Training on Health Beliefs and Cardiac Rehabilitation in Patients with Acute Myocardial Infarction After Intervention Therapy

Jin Wang — 2025-04-04

Objective: To explore the effect of narrative nursing combined with exercise training on health beliefs and cardiac rehabilitation in patients with acute myocardial infarction (AMI) after interventional treatment. Methods: A total of 111 patients with acute myocardial infarction (AMI) who received interventional therapy in Department of Cardiology of Hefei First People’s Hospital from January 2022 to September 2023 were selected as the study subjects. They were randomly divided into a control group (n = 55) and a study group (n = 56) using a random table method. Both groups received routine nursing care, while the control group received exercise training on top of it. The study group received narrative nursing care on top of the control group. Both groups were intervened until the patients were discharged. The health beliefs, heart function, psychological status, and quality of life after intervention were compared between two groups using a 6-minute walk test (6MWT). Results: After intervention, the scores of the TSK-SV Heart in all dimensions (fear of movement, functional disorders, risk perception, and avoidance of movement) decreased in both groups, and the study group was lower than the control group, with a statistical significant difference (P < 0.05). After intervention, the scores of the Self Rating Anxiety Scale (SAS) and Self Rating Depression Scale (SDS) in both groups decreased, and the study group was lower than the control group, with a statistical significant difference (P < 0.05). After intervention, both groups showed an increase in left ventricular ejection fraction (LVEF) and left ventricular early diastolic peak flow velocity/left ventricular late diastolic peak flow velocity (E/A), with the study group being higher than the control group. The left ventricular end diastolic diameter (LVEDD) and left atrial volume index (LAVI) decreased, and the study group was lower than the control group, with statistical significant differences (P < 0.05). The walking distance of the study group at 6MWT (488.8 ± 31.4) m was greater than that of the control group (425.54 ± 30.7) m, with statistical significant differences (P < 0.05). The quality of life measurement scale (CROQ-PTCA-Post) of the study group after coronary intervention treatment had higher scores in all dimensions (physical function, satisfaction, psychosocial function, adverse reactions, symptoms, cognitive function) than the control group, with statistical significant differences (P < 0.05). Conclusion: Narrative nursing combined with exercise training can enhance the health beliefs of AMI patients towards exercise training after intervention therapy, which is beneficial for cardiac rehabilitation and can improve psychological status and quality of life.

A Study on the Correlation between Fear of Disease Progression, Perceived Control, and Medical Coping in Patients with Coronary Heart Disease after PCI

Xue Li — 2025-04-04

This study aims to understand the current status of fear of disease progression (FoP) in patients with coronary heart disease (CHD) following percutaneous coronary intervention (PCI), and to explore the relationship between FoP levels, perceived control, and medical coping strategies in these patients. A total of 360 CHD patients who underwent PCI at Xijing Hospital in Shaanxi Province between June and November 2024 were selected using a convenience sampling method. Surveys included a general information questionnaire, the Fear of Progression Questionnaire-Short Form (FoP-Q-SF), the revised Control Attitudes Scale (CAS-R), and the Medical Coping Modes Questionnaire (MCMQ). Pearson correlation analysis was used to examine the relationships between disease perception, positive coping strategies, and FoP. A total of 360 patients completed the study. The average score for FoP in patients with CHD after PCI was 31.64 ± 4.61. FoP was negatively correlated with perceived control (r = -0.106, P < 0.01) and medical coping (r = -0.194, P < 0.01). Multivariate regression analysis showed that the type of intervention, family history of CHD, smoking status, perceived control, and total medical coping score were significant factors influencing FoP (P < 0.01). Enhancing perceived control and identifying positive coping strategies can improve FoP levels in patients with CHD after PCI. Therefore, clinicians should focus on perceived control and medical coping levels in patients and develop targeted interventions to alleviate negative emotions related to FoP.

The Efficacy of Whole-Course Local Simultaneous Integrated Boost Intensity-Modulated Radiotherapy in the Treatment of Locally Advanced Esophageal Cancer and Its Impact on Immune Function

Lei Yuan — 2025-04-04

Objective: To analyze the efficacy of whole-course local simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) on patients with locally advanced esophageal squamous cell carcinoma (ESCC). Methods: 88 patients with ESCC admitted to the hospital between October 2022 and October 2024 were selected and randomly divided into two groups using a random number table. The experimental group received SIB-IMRT treatment, while the control group received conventional intensity-modulated radiotherapy (C-IMRT). The objective remission rate, immune function, tumor markers, and adverse reaction rate were compared between the two groups. Results: The objective remission rate in the experimental group was higher than that in the control group (P < 0.05). Before treatment, there was no difference in immune function levels and tumor marker levels between the two groups (P > 0.05). After treatment, the immune function levels in the experimental group were better than those in the control group, and the tumor marker levels were lower than those in the control group (P < 0.05). The adverse reaction rate in the experimental group was lower than that in the control group (P < 0.05). Conclusion: SIB-IMRT can improve the objective remission rate of patients with ESCC, protect their immune function, down-regulate tumor marker levels, and prevent side effects after treatment.

Advances in the Study of Telemedicine in Patients With Schizophrenia

Mingyue Yang — 2025-04-03

This article reviews the concept of telemedicine, as well as the current status of its application in patients with schizophrenia, problems, and suggestions for improvement, with the aim of providing a reference for the application of telemedicine in patients with schizophrenia.

Predictive Value of Diaphragmatic Thickening Fraction Combined with Cough Peak Flow Rate for Weaning from Mechanical Ventilation

Yaqiang Wei — 2025-04-04

Objective: To investigate the predictive value of diaphragm thickening fraction (DTF) combined with cough peak expiratory flow (CPEF) on the success rate of weaning from mechanical ventilation. Methods: The clinical data of patients undergoing invasive mechanical ventilation via oral endotracheal intubation in the ICU of our hospital from January 2022 to December 2023 were studied. All patients underwent a 30-minute spontaneous breathing trial (SBT) using low-level pressure support ventilation (PSV) after meeting the clinical weaning screening criteria. Among them, 150 patients who met the clinical weaning criteria were weaned from the ventilator. They were divided into a successful weaning group (n=100) and a failed weaning group (n=50) based on the weaning outcome. Clinical data, including age, gender, APACHE II score, duration of mechanical ventilation, DTF, and CPEF, were collected from 150 patients. The differences in clinical data between the two groups were compared, and the correlation between DTF, CPEF, and the success rate of weaning was analyzed. Results: There were no significant differences between the two groups in gender ratio (χ2=0.884, P=0.347>0.05), age (t=0.350, P=0.727>0.05), and APACHE II score (t=1.295, P=0.197>0.05), but there was a significant difference in the duration of mechanical ventilation (t=3.766, P<0.001). The DTF and CPEF values in the successful weaning group were significantly higher than those in the failed weaning group (P<0.05). ROC curves were drawn to predict the weaning results using DTF, CPEF, and the combination of DTF and CPEF. The results showed that the specificity of the combination of DTF and CPEF was comparable to that of either metric alone, but the sensitivity and AUC were significantly higher than those of either metric alone. Conclusion: The combination of DTF and CPEF can be used as an effective indicator to evaluate the weaning efficacy of mechanically ventilated patients, which has important clinical significance for guiding clinical weaning treatment, improving the success rate of weaning, reducing the incidence of ventilator-associated pneumonia, and shortening the length of hospital stay.