Clinical Observation on the Combination of Yu Ping Feng San and Olopatadine in the Treatment of Chronic Urticaria
Download PDF
$currentUrl="http://$_SERVER[HTTP_HOST]$_SERVER[REQUEST_URI]"

Keywords

Yu Ping Feng San
Olopatadine
Chronic urticaria
Clinical efficacy

DOI

10.26689/dh.v2i2.7396

Submitted : 2024-06-18
Accepted : 2024-07-03
Published : 2024-07-18

Abstract

Objective: To investigate and analyze the clinical effect of treating patients with chronic urticaria with Yu Ping Feng San combined with olopatadine. Methods: The study period was from January 2023 to January 2024, 46 patients diagnosed with chronic urticaria were extracted as assessment samples, which were randomly divided into an observation group (n = 23) and a control group (n = 23) by using the method of medical record number random drawing. The treatment program for patients in the control group was olopatadine, and the treatment program for patients in the observation group was Yu Ping Feng San combined with olopatadine. The TCM symptom scores, urticaria activity scores (UAS7), itching VAS scores, clinical efficiency, recurrence rate, and incidence of adverse reactions between the two groups were compared. Results: The TCM symptom scores of the observation group were lower than those of the control group after treatment (P < 0.05); the UAS7 score and itching VAS score of the observation group were lower than those of the control group after treatment (P < 0.05); the clinical effective rate of the observation group was higher than that of the control group after treatment, and the recurrence rate was lower than that of the control group (P < 0.05); the comparison of the incidence rates of adverse reactions between the two groups did not show any significant difference (P < 0.05). Conclusion: The treatment effect of patients with chronic urticaria using Yu Ping Feng San combined with olopatadine is remarkable. This combined treatment can relieve the symptoms of Chinese medicine, control the progression of the disease, and reduce the degree of itching, with a lower recurrence rate and higher safety of the medication, which is suitable for popularization and application in healthcare institutions.

References

Guan JL, Lu JT, Kong ZZ, et al., 2022, Therapeutic Efficacy of Jiawei Yu Ping Feng San Combined with Citicoline Loratadine in the Treatment of Chronic Urticaria in the Elderly and the Effect on Patients’ Coagulation Indexes. Chinese Journal of Gerontology, 42(22): 5552–5555.

Shin Q, Li JC, Xiong WT, et al., 2022, Exploring the Mechanism of Action of Yu Ping Feng San in the Treatment of Chronic Urticaria based on Network Pharmacology and Molecular Docking Technology. Chinese Journal of Integrative Dermatology and Venereology, 21(5): 390–¬397.

Wen WB, Zhang H, Lin M, et al., 2022, Effect of Yu Ping Feng San Combined with Dicloretadine Treatment on Serum Inflammatory Factor Levels and Quality of Life of Children with Chronic Urticaria. China Medical Innovation, 19(17): 78–81.

Lin FC, 2022, Meta-analysis of the Efficacy of Yu Ping Feng San Combined with Levocetirizine in the Treatment of Chronic Urticaria. China Traditional Chinese Medicine Modern Distance Education, 20(12): 127–129.

Fu LH, Huang GY, 2023, Analysis of the Efficacy of Benzenesulfobetazin Tablets Combined with Yu Ping Feng San Granules in the Treatment of Chronic Urticaria. Primary Medical Forum, 27(34): 125–127.

Wang J, Yang GS, 2021, Clinical Study on the Treatment of Chronic Urticaria with Loratadine Tablets Combined with Yu Ping Feng San Capsule. Journal of Anhui University of Traditional Chinese Medicine, 40(1): 34–37.

Li LL, Ma TT, 2021, Effectiveness Analysis of Yu Ping Feng San Plus Reduction Combined with Ebastine in the Treatment of Chronic Urticaria. China Practical Medicine, 16(25): 178–180.

Duan ZG, Wang XR, 2021, Effectiveness and Safety of Duopi Drink combined with Yu Ping Feng San Plus Reduction in the Treatment of Chronic Urticaria. Clinical Medicine Research and Practice, 6(7): 116–117 + 126.

Yao LP, Liu Y, Cheng M, et al., 2021, Observations on the Efficacy of Baixiao Moxibustion Combined with Yu Ping Feng San in the Treatment of Wind-Cold Type Chronic Urticaria. Shanxi Traditional Chinese Medicine, 2021(6): 32–33.

Zhang X, Liu SY, Li ZL, 2021, Therapeutic Effect of Jiawei Yu Ping Feng San combined with Citicoline Loratadine Tablets on Chronic Urticaria. Henan Medical Research, 30(17): 3206–3208.