Dermatological Health

A Case of Cosmetic-Related Eyebrow Loss: Combined Analysis Using Dermoscopy and Reflectance Confocal Microscopy

Jiaming Chen — 2025-12-31

This case report presents a 23-year-old female patient who developed eyebrow and follicular damage following the use of cosmetic products. The patient experienced gradual eyebrow thinning and hair loss after applying eyebrow powder. Physical examination was unremarkable, while dermoscopy revealed hair breakage, follicular damage, and the presence of the black dot sign. Reflectance confocal microscopy showed infiltration of inflammatory cells. Patch testing was strongly positive. After excluding other systemic conditions, a diagnosis of cosmetic-induced follicular damage was established based on the clinical findings and test results. Discontinuation of the cosmetic product led to eyebrow regrowth. This case underscores the potential risks of cosmetic ingredients to hair health and highlights the utility of non-invasive diagnostic techniques for clinical evaluation.

Postoperative 3D-Printed Scar Device Aids in “Restoring the Ear to Its Original Appearance”

Binyu Zhuang — 2025-12-31

Background: To investigate the efficacy of a postoperative 3D-printed scar device in the treatment of ear scars. Methods: The clinical data of six patients with ear keloids admitted to the Outpatient Department of Dermatology at the Fourth Affiliated Hospital of Harbin Medical University from August 2025 to September 2025 were selected. Following ear scar excision, a 3D-printed scar device was applied for 3 months to assess its therapeutic effect on patients’ ear keloids. Results: The keloids of the patients in the treatment group were significantly reduced compared to before treatment. Conclusion: The postoperative 3D-printed scar device is an effective method for treating ear keloids, and it significantly improves the precision, comfort, and efficacy of keloid treatment.

The Impact of Intrinsic and External Environmental Factors on Treatment Efficacy in Patients with Chronic Spontaneous Urticaria: A Single-center Retrospective Study

Song Li — 2025-12-31

Purpose: This study aimed to explore the association between patient-intrinsic factors, environmental exposures, and improvement in psychosocial adaptation among individuals with chronic spontaneous urticaria (CSU). Methods: We conducted a single-center retrospective cohort study by reviewing medical records of 84 CSU patients aged 18–65 years who attended a tertiary dermatology outpatient clinic between January 2023 and January 2024, with follow-up of at least 3 months. Data on demographic characteristics, disease severity (measured by UCT score), and psychosocial adaptation (assessed via the Chinese version of the Patient Attitude and Self-Adaptation Questionnaire, PASQ-CSD) were extracted from electronic health records, while environmental variables—including monthly averages of temperature, humidity, PM2.5 levels, and pollen concentration—were obtained from national meteorological and environmental monitoring platforms. Improvement in psychosocial adaptation was defined as an increase of ≥5 points in PASQ score during 3–6 months of follow-up. Results: The mean age of participants was 44.27 ± 14.86 years, with 55.9% being female. Although no significant differences were observed in UCT scores (P = 0.402) or PARS-3 scores across treatment groups, PASQ scores showed statistically significant intergroup variation (P = 0.015). Occupational distribution differed significantly among groups (P = 0.034), whereas marital status did not (P = 0.219). No direct causal relationship was identified between medication type and psychological improvement; however, findings suggest that sociodemographic roles and environmental stressors may act as potential modifiers. Conclusion: These results indicate that psychosocial adaptation in CSU patients is influenced by multiple contextual factors, highlighting the need for integrated biopsychosocial assessment in clinical management and supporting future prospective studies on environment–psychology interactions.