Clinical Observation on the Combination of Yu Ping Feng San and Olopatadine in the Treatment of Chronic Urticaria

Abstract

Objective: To investigate and analyze the clinical effect of treating patients with chronic urticaria with Yu Ping Feng San combined with olopatadine. Methods: The study period was from January 2023 to January 2024, 46 patients diagnosed with chronic urticaria were extracted as assessment samples, which were randomly divided into an observation group (n = 23) and a control group (n = 23) by using the method of medical record number random drawing. The treatment program for patients in the control group was olopatadine, and the treatment program for patients in the observation group was Yu Ping Feng San combined with olopatadine. The TCM symptom scores, urticaria activity scores (UAS7), itching VAS scores, clinical efficiency, recurrence rate, and incidence of adverse reactions between the two groups were compared. Results: The TCM symptom scores of the observation group were lower than those of the control group after treatment (P < 0.05); the UAS7 score and itching VAS score of the observation group were lower than those of the control group after treatment (P < 0.05); the clinical effective rate of the observation group was higher than that of the control group after treatment, and the recurrence rate was lower than that of the control group (P < 0.05); the comparison of the incidence rates of adverse reactions between the two groups did not show any significant difference (P < 0.05). Conclusion: The treatment effect of patients with chronic urticaria using Yu Ping Feng San combined with olopatadine is remarkable. This combined treatment can relieve the symptoms of Chinese medicine, control the progression of the disease, and reduce the degree of itching, with a lower recurrence rate and higher safety of the medication, which is suitable for popularization and application in healthcare institutions.