Objective: To compare the therapeutic effect of video-assisted thoracoscopic surgery and traditional thoracotomy in patients with esophageal cancer. Methods: 60 patients with esophageal cancer who were treated from February 2022 to February 2023 were randomly divided into groups. Video-assisted thoracoscopic surgery was included in group A, and thoracotomy was included in group B. The curative effects of esophageal cancer surgery were compared. Results: All surgical indexes in group A were better than those in group B (P < 0.05); interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-alpha) levels in group A were lower than those in group B (P < 0.05); the postoperative SF-36 score in group A was higher than that in group B (P < 0.05); the postoperative complication rate in group A was lower than that in group B (P < 0.05). Conclusion: Video-assisted thoracoscopic treatment for patients with esophageal cancer can reduce postoperative inflammatory response and reduce surgical trauma, which is safe and efficient.
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