Objective: To explore the application value of amlodipine combined with enalapril in the treatment of elderly hypertension. Methods: A total of 600 hypertensive patients admitted between May 2020–2023 were recruited and divided into the study group and the control group, with 300 cases in each group, using a double-blind mechanism. The study group was treated with enalapril and amlodipine, while the control group was treated with enalapril. The changes in vascular endothelium, blood pressure performance, pulse pressure level, and drug side effects were compared between the groups. Results: Before treatment, the changes in vascular endothelium showed no significant difference between the groups (P > 0.05); after treatment, the changes in the study group were significantly better than the control group (P < 0.05). Before treatment, the performance of systolic and diastolic blood pressures in the two groups showed no significant difference (P > 0.05); after treatment, the performance in the study group was lower than that in the control group (P < 0.05). Before treatment, the pulse pressure levels of the two groups showed no significant difference (P > 0.05); after treatment, the pulse pressure levels of the study group were significantly better than that of the control group (P < 0.05). The side effects of medication in the study group were significantly lower than those in the control group (P < 0.05). Conclusion: Amlodipine combined with enalapril has a higher curative effect in the treatment of elderly hypertension, which is worthy of promotion.
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