Keywords
Churg-Strauss syndrome
Heart failure
Submitted : 2024-03-30
Accepted : 2024-04-14
Published : 2024-04-29
Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a rare pathology that belongs to a group of diseases characterized by necrotizing vasculitis of small and medium-sized systemic blood vessels. Symptomatic cardiovascular involvement occurs in 27%–47% of cases of EGPA and is one of the most severe manifestations. The diagnosis is usually confirmed by eosinophilic infiltration observed in tissue biopsy, but with the recent inclusion of cardiac magnetic resonance imaging (MRI), the former can be replaced. Early diagnosis is important because timely treatment is often associated with improvement.
References
Jennette JC, Falk RJ, Bacon PA, et al., 2013, 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum, 65(1): 1–11. https://doi.org/10.1002/art.37715
Nguyen Y, Guillevin L, 2018, Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss). Semin Respir Crit Care Med, 39(4): 471–481. https://doi.org/10.1055/s-0038-1669454
Qiao L, Gao D, 2016, A Case Report and Literature Review of Churg-Strauss Syndrome Presenting with Myocarditis. Medicine, 95(51): e5080. https://doi.org/10.1097/MD.0000000000005080
McAleavey N, Millar A, Pendleton A, 2013, Cardiac Involvement as the Main Presenting Feature in Eosinophilic Granulomatosis with Polyangiitis. BMJ Case Rep, 2013: bcr2013009394. https://doi.org/10.1136/bcr-2013-009394
Groh M, Pagnoux C, Baldini C, et al., 2015, Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss) (EGPA) Consensus Task Force Recommendations for Evaluation and Management. Eur J Intern Med, 26(7): 545–553. https://doi.org/10.1016/j.ejim.2015.04.022
Churg J, Strauss L,1951, Allergic Granulomatosis, Allergic Angiitis, and Periarteritis Nodosa. Am J Pathol, 27(2): 277–301.
Mahr A, Guillevin L, Poissonnet M, et al., 2004, Prevalences of Polyarteritisnodosa, Microscopic Polyangiitis, Wegener’s Granulomatosis, and Churg-Strauss Syndrome in a French Urban Multiethnic Population in 2000: A Capture-Recapture Estimate. Arthritis Rheum, 51(1): 92–99. https://doi.org/10.1002/art.20077
Mahr A, Moosig F, Neumann T, et al., 2014, Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss): Evolutions in Classification, Etiopathogenesis, Assessment and Management. Curr Opin Rheumatol, 26(1): 16–23. https://doi.org/10.1097/BOR.0000000000000015
Dallos T, Heiland GR, Strehl J, et al., 2010, CCL17/Thymus and Activation-Related Chemokine in Churg-Strauss Syndrome. Arthritis Rheum, 62(11): 3496–3503. https://doi.org/10.1002/art.27678
Pakbaz M, Pakbaz M, 2020, Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis: A Meta-Analysis of 62 Case Reports. J Tehran Heart Cent, 15(1): 18–26.
Courand PY, Croisille P, Khouatra C, et al., 2012, Churg-Strauss Syndrome Presenting with Acute Myocarditis and Cardiogenic Shock. Heart Lung Circ, 21(3): 178–181. https://doi.org/10.1016/j.hlc.2011.09.002
Baccouche H, Yilmaz A, Alscher D, et al., 2008, Images in Cardiovascular Medicine. Magnetic Resonance Assessment and Therapy Monitoring of Cardiac Involvement in Churg-Strauss Syndrome. Circulation, 117(13): 1745–1749. https://doi.org/10.1161/CIRCULATIONAHA.107.721738
Mavrogeni S, Manoussakis MN, Karagiorga TC, et al., 2009, Detection of Coronary Artery Lesions and Myocardial Necrosis by Magnetic Resonance in Systemic Necrotizing Vasculitides. Arthritis Rheum, 61(8): 1121–1129. https://doi.org/10.1002/art.24695
Mavrogeni S, Karabela G, Gialafos E, et al., 2013, Cardiac Involvement in ANCA (+) and ANCA (-) Churg-Strauss Syndrome Evaluated by Cardiovascular Magnetic Resonance. Inflamm Allergy Drug Targets, 12(5): 322–327.
Dennert RM, van Paassen P, Schalla S, et al., 2010, Cardiac Involvement in Churg-Strauss Syndrome. Arthritis Rheum, 62(2): 627–634. https://doi.org/10.1002/art.27263