Keywords
Kidney-Yang deficiency
Hypertension
Submitted : 2025-03-05
Accepted : 2025-03-20
Published : 2025-04-04
Abstract
Objective: To observe the efficacy of combined external treatment of traditional Chinese medicine (TCM) in intervening hypertension with kidney-Yang deficiency by regulating the RASS system. Methods: A total of 61 patients with subacute hypertension and kidney-Yang deficiency admitted to our hospital from December 2024 to March 2025 were selected. The western medicine treatment group was treated with amlodipine benzenesulfonate and instructed to take antihypertensive western medicine regularly. The TCM external treatment group received auricular acupuncture, auricular point pressing with beans, and acupoint application based on the treatment of the Western medicine group. Laboratory indicators (including angiotensin II, aldosterone, and renin), blood pressure changes, and TCM syndrome scores were compared between the two groups after 4 weeks of treatment. Results: After treatment, there were no statistically significant differences in angiotensin II, aldosterone, and renin between the TCM external treatment group and the Western medicine treatment group (P < 0.05). There was no statistical significance in blood pressure measurements from the 1st to the 8th time between the two groups (P > 0.05). However, both systolic and diastolic blood pressures in the TCM external treatment group showed statistically significant differences between the 8th and 1st measurements (P < 0.05), while only systolic blood pressure in the western medicine treatment group showed a statistically significant difference (P < 0.05). The blood pressure in the TCM external treatment group decreased steadily from the 1st to the 8th measurement, whereas it did not decrease significantly in the Western medicine treatment group. The TCM external treatment group had significantly better scores in terms of headache and dizziness, cold limbs or back, frequent or involuntary nocturia, fatigue and laziness to speak, shortness of breath and weakness, and other TCM syndromes compared to the control group (P < 0.05). Conclusion: The combination of TCM external treatment and Western medicine has a good antihypertensive effect in treating subacute hypertension with kidney-Yang deficiency and can effectively improve clinical symptoms.
References
Yan S, 2018, Clinical Observation on the Treatment of Hypertension of Liver Yang Hyperactivity Type with Combined Internal and External Therapies. Guangming Journal of Chinese Medicine, 33(5): 615–616.
Zhang X, Wang Z, Li Y, 2024, Acupoint Application for the Treatment of Primary Hypertension with Hyperactivity of Liver Yang and Insufficiency of Kidney Yin. Guangming Journal of Chinese Medicine, 39(24): 4984–4987.
Tang W, Chen Y, Tang K, 2021, Clinical Study on the Treatment of Primary Hypertension of Liver Yang Hyperactivity Type by Applying Fudi Chouxin Prescription at Yongquan Acupoint. Hebei Journal of Traditional Chinese Medicine, 43(10): 1632–1635 + 1639.
Chen Z, Liu X, 2023, A Brief Review of Research Progress on Traditional Chinese Medicine for Hypertension of Liver Yang Hyperactivity Type. Kangyi, 2023(6): 281–283.
Huang M, Cui J, 2024, Research Progress on the Treatment of Senile Hypertension with Traditional Chinese Medicine Dialectics Combined with External Therapy. Clinical Personalized Medicine, 3(4): 2237–2242.
Guo M, Zhao J, Shi W, et al., 2021, Research Progress on the Treatment of Hypertension with Cognitive Impairment by Traditional Chinese Medicine. Guiding Journal of Traditional Chinese Medicine and Pharmacology, 27(7): 126–131.
Li W, Xia Q, Li B, et al., 2019, Clinical Study on Adjuvant Treatment of Primary Hypertension of Liver Yang Hyperactivity Type with Wu Zhu Yu Applied at Taichong and Yongquan Acupoints. Journal of New Chinese Medicine, 51(4): 234–236.
Chen F, 2019, Evaluation of the Efficacy of Acupoint Application of Xuan Yun Fang on Left Atrial Function in Patients with Hypertension of Liver Yang Hyperactivity Type Using Velocity Vector Imaging Technology. Guangming Journal of Chinese Medicine, 34(13): 2031–2034.
Li S, Zhang J, 2019, Clinical Study on the Treatment of Hypertensive Cerebral Hemorrhage with Traditional Chinese Medicine External Therapy Combined with Hyperbaric Oxygen Therapy. Modern Journal of Integrated Traditional Chinese and Western Medicine, 28(10): 1071–1075.
Zhang H, Xu Y, Chen H, et al., 2022, Observation on the Effect of Zhang’s “Internal and External Treatment” in the Treatment of H-Type Hypertension. Chinese Rural Medicine, 29(14): 3–5.
Li K, Zhu Y, 2021, Analysis of the Effect of Bushen Tiaoya Tang, Acupuncture, and Moxibustion Combined with Western Medicine in the Treatment of Kidney Deficiency Type Hypertension. Chinese Medical Innovation, 18(1): 89–92.
Li Y, 2023, Clinical Observation of Professor Ren Jixue’s Foot Soaking Prescription Combined with Acupoint Application in the Treatment of CKD3 with Hypertension (Spleen and Kidney Yang Deficiency Syndrome), thesis, Changchun University of Chinese Medicine.
Huang G, Chen X, Zhang L, et al., 2008, Clinical Observation on the Treatment of 60 Cases of Hypertension with Deng Tietao’s Foot Bathing Prescription. Liaoning Journal of Traditional Chinese Medicine, 35(7): 1041–1042.