Research Progress on the Treatment of Depression with Chinese Herbal Medicine

Wed, 28 May 2025 11:45:03 +0800

Depression is a common affective disorder characterized by significant and persistent low mood. Traditional Chinese medicine (TCM) attributes depression to emotional disturbances, classifying it as a mood disorder. Chinese herbal formulas have unique advantages and higher safety profiles in treating depression, despite challenges such as complexity in herb combinations, varying efficacy, and potential side effects. Currently, Chinese patent medicines and decoctions are widely used in the clinical treatment of depression, yielding positive results. This article summarizes recent research on the pharmacological effects of Chinese herbal formulas and single herbs with antidepressant properties, analyzing them from three aspects: chemical composition, pharmacological mechanism, and adverse reactions. The aim is to provide references for the clinical application of Chinese herbal formulas in treating depression and to suggest directions for future research.

Evaluation of the Therapeutic Effect of Cerebrospinal Fluid Replacement in Subarachnoid Hemorrhage and Study on the Endpoint of Replacement Volume

Wed, 28 May 2025 11:48:00 +0800

Objective: To evaluate the therapeutic effect of cerebrospinal fluid (CSF) replacement in subarachnoid hemorrhage (SAH) and analyze the endpoint of replacement volume. Methods: 36 patients with spontaneous or traumatic SAH and intracerebral hemorrhage breaking into the subarachnoid space received by the hospital from August 2024 to April 2025 were selected. Different volumes of CSF were replaced with routine operation, and the clinical efficacy was analyzed. Results: All 36 patients were effective without any complications. In terms of replacement volume, the patients in the clear CSF replacement group had a greater decrease in VAS scores immediately and at 48 hours, and their symptom relief was more significant. The difference was statistically significant by t-test. Regarding the average frequency of CSF replacement, the control group had a higher average frequency than the clear group, but there was no statistical difference by the rank sum test. Conclusion: CSF replacement therapy can effectively improve clinical symptoms in patients with SAH. In terms of replacement volume, patients in the clear CSF replacement group had a greater decrease in VAS scores immediately and at 48 hours, with more significant symptom relief. Therefore, CSF replacement should be thorough, has high safety, and is worthy of clinical promotion.

Clinical Neuroscience Research

Research Progress on the Treatment of Depression with Chinese Herbal Medicine

Evaluation of the Therapeutic Effect of Cerebrospinal Fluid Replacement in Subarachnoid Hemorrhage and Study on the Endpoint of Replacement Volume