Clinical Effect of the Modified Huatan Tongluo Formula on Acute Cerebral Infarction Patients with Wind-Phlegm Obstruction Syndrome
Download PDF


Acute cerebral infarction
Wind-phlegm obstruction syndrome
Modified Huatan Tongluo formula



Submitted : 2023-12-11
Accepted : 2023-12-26
Published : 2024-01-10


Objective: To analyze the clinical effect of the modified Huatan Tongluo formula on acute cerebral infarction patients with wind-phlegm obstruction syndrome. Methods: 70 cases of acute cerebral infarction with wind-phlegm blocking syndrome admitted from May 2022 to May 2023 were selected as the study subjects. The subjects were divided into a control group and an observation group by randomized numerical table method, each with 35 cases; the control group was treated with conventional Western medicine, and the observation group was treated with the modified Huatan Tongluo Formula in addition to conventional treatment. The two groups were compared in terms of traditional Chinse medicine (TCM) evidence points, quality of life, clinical efficacy, and adverse reactions. Results: Before treatment, there were no significant differences in each index between the two groups of patients (P > 0.05); after treatment, the observation group scored better in terms of TCM evidence and quality of life compared to the control group. Besides the total clinical efficacy of the treatment received in the observation group was also higher than that of the control group (P < 0.05). However, there was no significant difference in terms of incidence of adverse reactions between the two groups (> 0.05). Conclusion: The modified Huatan Tongluo formula can improve the clinical symptoms and the quality of life of acute cerebral infarction patients with wind-phlegm obstruction syndrome.


Wang S, Yang Y, Bao Y, 2021, Effect of Jiawei Huatan Tongluo Decoction on the Expression of Serum Brain Injury Markers and Clinical Efficacy in Patients with Wind-Phlegm Obstruction in the Acute Stage of Cerebral Infarction. Sichuan Traditional Chinese Medicine, 39(1): 129–132.

Tong X, Cheng X, Zhang L, 2021, Clinical Effect of Self-Proposed Formula for Treating Wind-Phlegm-Blocking Acute Cerebral Infarction. China Medicine Herald, 18(29): 146–149.

Han X, Liu M, Lian Z, et al., 2016, Evaluation Study on the Clinical Application of the Guidelines for Diagnosis and Treatment of Common Diseases in Traditional Chinese Medicine. Proceedings of the 2016 Annual Meeting of the Cardiovascular Disease Branch of the Chinese Society of Traditional Chinese Medicine. 2016: 8–15.

Gong C, Zhou D, Yang R, et al., 2021, Mechanism Study on the Treatment of Cerebral Infarction by Huatan Tongluo Decoction Based on GEO Data Mining and Network Pharmacology. World TCM, 16(9): 1406–1412.

Gong C, Yang R, Fu X, et al., 2021, The Effect of Resolving Phlegm and Clearing the Channel Soup Combined with Butylphthalide Sodium Chloride Injection on Collateral Circulation and Cerebral Blood Perfusion in Patients with Acute Cerebral Infarction. China Journal of Traditional Chinese Medicine Information, 28(6): 94–99.

Rao Q, Tan Z, 2022, Effect of Qufeng Huatan Tongluo Decoction Combined with Acupuncture and Massage on Upper Limb Muscle Strength in Hemiplegic Patients with Wind-Phlegm Stasis Type Acute Cerebral Infarction. Sichuan Traditional Chinese Medicine, 40(3): 163–166.

Liu R, Ma L, Jiang L, et al., 2023, The Effect of Huatan Tongluo Decoction on Neurological Function and Serum Amyloid A and Glycated Serum Protein in Patients with Wind-Phlegm-Obstructed Cerebral Infarction. Anhui Medicine, 27(2): 396–400.

Zhang Y, Zhao R, Zhang Z, et al. 2022, Study on the Clinical Efficacy and Inflammatory Mechanism of Clearing Heat and Dissipating Dampness Formula in the Treatment of Cerebral Infarction in the Post-Infarction Period. Hebei Journal of Traditional Chinese Medicine, 37(1): 9–12.

Xia Y, Xu J, Wang H, et al., 2022, Efficacy of Self-Proposed Huatan Tongluo Formula in Treating Phlegm and Blood Stasis Obstruction in Early Recovery from Cerebral Infarction and its Effect on Cerebral Hemodynamics and Vascular Nerve Repair Factors. China Journal of Traditional Chinese Medicine Information, 29(2): 109–114.

Chen Y, Guo Z, Tu J, et al., 2021, Clinical Study on Early Treatment of Acute Small Artery Occlusion Type Cerebral Infarction with Wind-Phlegm Stasis Evidence by Huoxue Huatan Tongluo Formula. Modern Journal of Integrative Medicine, 30(4): 369–374 + 393.

Cai X, Wang Z, Shi S, 2021, Efficacy and Effect on Platelet Parameters in Treating Acute Cerebral Infarction with Huatan Tongluo Decoction. Journal of Emergency in Traditional Chinese Medicine, 30(5): 846–848.

Hu J, He J, 2021, Study on the Effect of Waking up the Brain and Opening Up the Orifices by Acupuncture Combined with Xifeng Huatan Tongluo Fuzheng Tang Decoction in the Treatment of Spastic Hemiplegia After Acute Cerebral Infarction. Journal of Practical Heart, Cerebral, Pulmonary, and Vascular Diseases, 29(8): 89–94.