摘要
Objective: To compare clinical outcomes of percutaneous vertebroplasty (PVP) through different surgical approaches and bone cement distribution in the treatment of osteoporotic vertebral compression fractures (OVCF). Methods: The clinical data of 231 patients with OVCF who underwent PVP from June 2020 to June 2022 were retrospectively analyzed. Clinical characteristics and surgical data were collected for statistical analysis. The total patients were divided into a unilateral approach group (Group UA) and a bilateral approach group (Group BA) according to different surgical approaches. Then, patients in Group BA were divided into a continuous bone cement group (Group CBC) and a discontinuous bone cement group (Group DBC) according to the distribution of bone cement. Results: In each group, the postoperative visual analog scale (VAS) score and Oswestry disability index (ODI) score were significantly decreased (P < 0.001). The operation time and fluoroscopy times of Group UA were less than those of Group BA (P < 0.001). However, compared with Group BA, Group UA had a lower mean VAS score (P = 0.013) and ODI score (P = 0.004) at the last follow-up. The VAS (P = 0.032) and ODI (P = 0.024) scores in the CBC group were significantly lower than those in the DBC group at the last follow-up. Conclusions: Unilateral PVP presented several advantages over bilateral PVP, particularly in terms of shorter surgery time, less fluoroscopy frequency, and less trauma. Continuous bone cement was closely related to good clinical outcomes. In clinical practice, we suggest unilateral PVP is performed for patients and ensure the continuity of bone cement for better clinical outcomes.
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