Background: The treatment and management of diabetic foot significantly impact the quality of life (QoL) of patients, yet studies concerning the effects of toe amputation on QoL are relatively limited. Methods: This study included 12 diabetic foot patients with Wagner Grade 4 who underwent toe amputation. Using the Cardiff Wound Impact Schedule (CWIS), we systematically assessed their QoL before and after the surgery. Results: Data indicated that there were significant improvements in multiple areas of QoL post-surgery. Particularly in the domains of “overall quality of life” and “well-being,” average scores demonstrated noticeable declines compared to pre-surgery levels. Statistical analysis further confirmed the significance of these results. Conclusion: Toe amputation holds significant value in enhancing the QoL for diabetic foot patients. This study provides robust evidence for clinical decision-making, emphasizing that treatment choices should consider the QoL of the patient in addition to physiological outcomes.
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