Keywords
Osteoporotic fracture
Effective rate
Submitted : 2023-11-26
Accepted : 2023-12-11
Published : 2023-12-26
Abstract
Objective: To observe the clinical effect of modified and subtracted Dipsacus Decoction in the treatment of osteoporotic fractures (OPF). Methods: 60 OPF cases were divided into two groups based on the double-blind method. Both groups underwent fracture reduction under X-ray guidance and took calcitriol soft capsules simultaneously, while Dipsacus Decoction was added to the observation group. The clinical treatment effectiveness, fracture healing time, bone density, laboratory indicators, and incidence of adverse reactions of the two groups were compared. Results: The total effective rate of clinical treatment in the observation group was higher than that in the control group, the fracture healing time was shorter than that of the control group, and the bone density and laboratory indicators after treatment were better than those of the control group (P < 0.05). There were no severe adverse reactions in either group. Conclusion: The addition and subtraction of Dipsacus Decoction based on conventional Western medicine treatment for OPF can further improve the effectiveness of clinical treatment and speed up fracture healing, which is worthy of promotion.
References
Zhang W, Chen K, Dong Q, et al., 2022, Effects of Adjuvant Treatment with Bushen Huoxue Zhuanggu Decoction on Postoperative Healing of Osteoporotic Fractures and Serum ?-CTX and Crosslaps. Hainan Medicine, 33(21): 2752–2755.
Wang H, Li P, Zhang B, et al., 2023, Effect of Self-Prepared Bushen Dipsacus Decoction Combined with Conventional Western Medicine Therapy on the Postoperative Efficacy and Bone Turnover Markers of Osteoporotic Vertebral Compression Fractures in Older People. International Journal of Traditional Chinese Medicine, 45(3): 293–297.
Bai J, Ma Y, Kong W, 2022, Decoction Combined with Percutaneous Vertebroplasty in Treating Osteoporotic Vertebral Compression Fractures. Practical Clinical Integration of Traditional Chinese and Western Medicine, 22(19): 100–103.
Qiu G, Pei F, Hu Z, et al., 2018, Chinese Guidelines for the Diagnosis and Treatment of Osteoporotic Fractures - Principles of Diagnosis and Treatment of Osteoporotic Fractures. Heilongjiang Science, 9(2): 85–88, 95.
Zheng X, 2002, Guiding Principles for Clinical Research of New Traditional Chinese Medicines, China Medical Scienceand Technology Press, Beijing.
Ding X, He W, Zhao Y, 2023, Effect of Huoxue Yigu Decoction-Assisted Kyphoplasty on Bone Healing and Postoperative Lumbar Function Recovery in Elderly Patients with Osteoporotic Thoracolumbar Fractures. International Traditional Chinese Medicine Journal of Traditional Chinese Medicine, 45(7): 823–828.
Qian X, He B, 2021, Application of Xugu Zhuyu Decoction After PFNA for Osteoporotic Intertrochanteric Fractures. Chinese Journal of Traditional Chinese Medicine Science and Technology, 28(4): 652–654.
Liu T, Liu Q, 2021, Clinical Observation on Treating Osteoporotic Colles Fracture in Older People with Manual Reduction and Small Splint Fixation Combined with Jiegu Xujin Decoction. Journal of Anhui University of Traditional Chinese Medicine, 40(4): 28–32.
Fang M, Zheng M, Wang C, 2022, Observation on the Application Effect of Yishen Jiegu Decoction After PFNA Surgery for an Intertrochanteric Fracture in the Elderly. China Traditional Chinese Medicine Science and Technology, 29(4): 594–596.
Xu S, Fang L, Chen Y, et al., 2021, Observation on the Application Effect of Bushen Yugu Decoction in the Elderly with Osteoporotic Spinal Compression Fracture After PKP Surgery. China Traditional Chinese Medicine Science and Technology, 28(4): 625–626.
Jiang L, Lou Y, 2022, The Clinical Effect of Dipsacus Decoction in Treating Surgical Patients with Thoracolumbar Osteoporotic Fractures. Chinese Journal of Integrated Traditional Chinese and Western Medicine Surgery, 28(1): 79–83.
Ren Y, 2021, Study on the Clinical Effectiveness of Dipsusta Jiegu Decoction in the Treatment of Limb Fractures. Chinese Disability Medicine, 29(2): 67–68.
Li W, 2019, Analysis of Dipsacus Decoction’s Effectiveness in Treating Patients with Limb Fractures. Journal of Mathematical Medicine, 32(12): 1841–1842.
Guo L, 2019, Case Analysis of Postoperative Treatment of Metacarpophalangeal Fractures with Modified Diduanjiegu Decoction. World Latest Medical Information Abstracts (Continuous Electronic Journal), 19(66): 229, 232.
Zhong B, Fan C, Pan Z, et al., 2023, Clinical Effect of Modified Dipsacus Decoction in Treating Osteoporotic Fractures. Modern Hospital, 23(7): 1132–1133, 1137.